~9 spots leftby Apr 2026

A Study to Investigate the Analgesic Efficacy of AZD2423 Compared With Placebo After 28 Days Treatment in Patients With Painful Diabetic Polyneuropathy

Recruiting in Palo Alto (17 mi)
+19 other locations
Age: 18+
Sex: Any
Travel: May Be Covered
Time Reimbursement: Varies
Trial Phase: Phase 2
Waitlist Available
Sponsor: AstraZeneca
Prior Safety Data

Trial Summary

What is the purpose of this trial?

A study to investigate the analgesic efficacy of AZD2423 compared with placebo after 28 days treatment in patients with painful diabetic polyneuropathy.

Research Team

BJ

Bror Jonzon

Principal Investigator

AstraZeneca R&D Södertälje

Eligibility Criteria

Inclusion Criteria

Provision of signed informed consent form
Males and female of non-child bearing potential patients aged 18 to 80 years
Patients with neuropathic pain due to painful diabetic polyneuropathy.

Treatment Details

Interventions

  • AZD2423 (Other)
  • Placebo (Other)
Participant Groups
3Treatment groups
Experimental Treatment
Placebo Group
Group I: AZD2423, 20 mgExperimental Treatment1 Intervention
Tablets, 20 mg once daily in the morning.
Group II: AZD2423, 150 mgExperimental Treatment1 Intervention
Tablets, 150 mg once daily in the morning.
Group III: PlaceboPlacebo Group1 Intervention
Tablets, placebo, once daily in the morning.

Find a Clinic Near You

Research Locations NearbySelect from list below to view details:
Research SitePhoenix, AZ
Research SiteLos Angeles, CA
Research SiteMiami, FL
Research SiteEtobicoke, Canada
More Trial Locations
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Who Is Running the Clinical Trial?

AstraZeneca

Lead Sponsor

Trials
4491
Patients Recruited
290,540,000+