Trial Summary
What is the purpose of this trial?The purpose of this research is to find out if using liposomal bupivacaine solution (bupivacaine liposome) injections during lower extremity revascularization surgery will lower the amount of narcotic drugs used during and following the procedure.
Eligibility Criteria
This trial is for English-speaking individuals scheduled for elective lower extremity revascularization surgery who are not on opioids for more than a week, do not have chronic pain, and have no allergies to local anesthetics or contraindications to regional anesthesia.Inclusion Criteria
You are scheduled for a planned surgery to improve blood flow in your legs.
Exclusion Criteria
Non-English speaking
Long-lasting pain
You have been taking opioid medications for more than 1 week.
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Participant Groups
The study is testing if injections of liposomal bupivacaine can reduce the need for narcotic drugs during and after leg artery surgery. Participants will either receive the actual drug or a placebo without knowing which one they get.
2Treatment groups
Experimental Treatment
Placebo Group
Group I: Liposomal Bupivacaine GroupExperimental Treatment1 Intervention
Subjects will receive an injection of liposomal bupivacaine during clinically indicated lower extremity revascularization surgery.
Group II: Placebo GroupPlacebo Group1 Intervention
Subjects will receive an injection of placebo during clinically indicated lower extremity revascularization surgery.
Find a Clinic Near You
Research Locations NearbySelect from list below to view details:
Mayo Clinic Health System - Eau ClaireEau Claire, WI
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Who Is Running the Clinical Trial?
Mayo ClinicLead Sponsor