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~18 spots leftby Apr 2026

Dietary Changes for Psoriatic Arthritis
(DIPSA Trial)

Recruiting in Palo Alto (17 mi)

+1 other location

Overseen byLihi Eder, MD, PhD

Age: 18+

Sex: Any

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Academic

Waitlist Available

Sponsor: University of Pennsylvania

No Placebo Group

Trial Summary

What is the purpose of this trial?

The purpose of this study is to learn whether changing diet impacts psoriatic arthritis (PsA).

Research Team

Alexis Ogdie-Beatty, MD, MSCE

Principal Investigator

University of Pennsylvania

Lihi Eder, MD, PhD

Principal Investigator

Women's College Hospital, University of Toronto

Eligibility Criteria

This trial is for adults aged 18-80 with a BMI between 25 and 40, diagnosed with Psoriatic Arthritis by a rheumatologist. Participants must have been on stable PsA treatment for at least three months, own a smartphone or be willing to use one provided, and are open to changing their diet for the study duration. Exclusions include eating disorders, certain medical conditions like insulin-dependent diabetes or advanced cancer, food allergies related to the study diets, inability to consent or read/write in English.

Inclusion Criteria

My Psoriatic Arthritis diagnosis is confirmed by a rheumatologist.

No history of eating disorders such as anorexia or bulimia

Owns and uses an iPhone or Android smart phone, or is willing to use a device provided by the study team

See 6 more

Exclusion Criteria

I am currently taking corticosteroids.

Inability to read and write in English

You are pregnant or could become pregnant.

See 6 more

Treatment Details

Interventions

Diet 1 (N/A)
Diet 2 (N/A)

Trial OverviewThe trial is testing two different diets' effects on psoriatic arthritis over a period of 24 weeks. Patients will be assigned one of these diets and will need to adhere strictly while attending regular follow-up visits. The goal is to see if dietary changes can improve symptoms associated with PsA.

Participant Groups

3Treatment groups

Active Control

Group I: Diet 1Active Control1 Intervention

Diet 1 will focus on the dietary pattern and monitor types of foods, supplementary nutrition, and provide nutritional support with a dietitian.

Group II: Diet 2Active Control1 Intervention

Diet 2 will focus on the dietary pattern and monitor the amount of food, complimentary nutrition, and nutritional support with a dietitian.

Group III: Diet 3Active Control1 Intervention

Diet 3 will focus on healthy dietary patterns and provide nutritional support with a dietitian.

Find a Clinic Near You

Who Is Running the Clinical Trial?

University of Pennsylvania

Lead Sponsor

Trials

2,118

Recruited

45,270,000+

Dr. Joan Lau

University of Pennsylvania

Chief Executive Officer since 2020

PhD in Neuroscience from the University of Cincinnati College of Medicine, MBA from the Wharton School of Business, BS in Bioengineering from the University of Pennsylvania