~21 spots leftby Apr 2026

Volumetric Laser Endomicroscopy With Intelligent Real-time Image Segmentation (IRIS)

Recruiting in Palo Alto (17 mi)
+2 other locations
AT
Overseen byArvind Trindade, MD
Age: 18+
Sex: Any
Travel: May Be Covered
Time Reimbursement: Varies
Trial Phase: Academic
Waitlist Available
Sponsor: Northwell Health
No Placebo Group

Trial Summary

What is the purpose of this trial?

This is a prospective randomized clinical trial examining how IRIS (Intelligent Real-time Image Segmentation) affects biopsy patterns in VLE (Volumetric laser endomicroscopy).

Research Team

AT

Arvind Trindade, MD

Principal Investigator

Northwell Health

Eligibility Criteria

Inclusion Criteria

18 years of age or older at the time of informed consent
Barrett's esophagus greater than 2 cm in length
Undergoing a scheduled upper endoscopy with VLE exam for surveillance as standard of care

Treatment Details

Interventions

  • IRIS (Diagnostic Test)
  • VLE (Diagnostic Test)
Participant Groups
2Treatment groups
Active Control
Group I: VLE with IRIS, followed by VLE without IRISActive Control2 Interventions
VLE (Volumetric laser endomicroscopy) performed with IRIS (Intelligent real-time image segmentation) imaging, followed by VLE alone.
Group II: VLE without IRIS, followed by VLE with IRISActive Control2 Interventions
VLE (Volumetric laser endomicroscopy) performed alone, followed by IRIS (Intelligent real-time image segmentation) imaging.

Find a Clinic Near You

Research Locations NearbySelect from list below to view details:
Mayo ClinicScottsdale, AZ
Mayo ClinicRochester, MN
North Shore University HospitalManhasset, NY
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Who Is Running the Clinical Trial?

Northwell Health

Lead Sponsor

Trials
481
Patients Recruited
470,000+

NinePoint Medical

Industry Sponsor

Trials
8
Patients Recruited
1,500+

Mayo Clinic

Collaborator

Trials
3427
Patients Recruited
3,221,000+