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Treadmill Walking for Knee Osteoarthritis

N/A
Recruiting
Research Sponsored by University of Delaware
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
For adults with knee osteoarthritis: presence of occasional to frequent knee pain, knee pain that is primarily in the medial knee joint compartment, minimal morning joint stiffness
For all participants: able to walk continuously for 30 minutes without an assistive device
Must not have
Cardiovascular or pulmonary conditions that limit daily activity or that preclude participation in exercise
Use of medications that affect balance
Timeline
Screening 3 weeks
Treatment Varies
Follow Up before and after the 30 minute treadmill walk
Awards & highlights
No Placebo-Only Group

Summary

This trial aims to study how fatigue impacts the risk of falling in adults aged 55-70 years with and without knee osteoarthritis. Participants will answer questionnaires, wear a physical activity measuring

Who is the study for?
This trial is for adults aged 55-70 who sometimes to often feel knee pain, mainly on the inside of the knee joint, with little morning stiffness. They should be able to walk for half an hour without help like a cane or walker.
What is being tested?
Researchers are testing how tiredness from walking might increase tripping and falling risks in people with and without knee osteoarthritis. Participants will fill out surveys, wear an activity tracker for up to a week, do a treadmill walk, and take tests before and after walking to measure fatigue's effects.
What are the potential side effects?
There may not be significant side effects from this study as it involves standard physical activities like walking on a treadmill. However, participants could experience general discomfort or aggravation of existing knee pain due to exercise.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
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I often have knee pain, mostly on the inner side, with little morning stiffness.
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I can walk for 30 minutes without help.

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:
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I have heart or lung conditions that limit my daily activities.
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I am taking medication that affects my balance.
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I have not had injections in my leg joints in the last 3 months.
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I currently have an acute illness or sores on my torso or legs.
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I have had a major injury or pain in my legs or back, not including knee arthritis.
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I use a device to help me walk.
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I have nerve damage due to diabetes.
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My BMI is over 35.
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My body weight is over 265 lbs.
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I have had an amputation of part of my leg.
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I have had a stroke or another neurological condition.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~beginning and end of 30 minute treadmill walk
This trial's timeline: 3 weeks for screening, Varies for treatment, and beginning and end of 30 minute treadmill walk for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Anterior reactive stepping
Anterior stability margins during walking
Knee extensor fatigability
+1 more

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

2Treatment groups
Experimental Treatment
Group I: Knee osteoarthritisExperimental Treatment1 Intervention
Group II: HealthyExperimental Treatment1 Intervention

Find a Location

Who is running the clinical trial?

National Institute of General Medical Sciences (NIGMS)NIH
299 Previous Clinical Trials
249,003 Total Patients Enrolled
University of DelawareLead Sponsor
162 Previous Clinical Trials
25,598 Total Patients Enrolled
6 Trials studying Osteoarthritis
414 Patients Enrolled for Osteoarthritis
~5 spots leftby Feb 2025