Treadmill Walking for Knee Osteoarthritis
Recruiting in Palo Alto (17 mi)
Age: 18+
Sex: Any
Travel: May Be Covered
Time Reimbursement: Varies
Trial Phase: Academic
Recruiting
Sponsor: University of Delaware
No Placebo Group
Trial Summary
What is the purpose of this trial?The goal of this clinical trial is to learn about how fatigue affects the risk of falling in adults aged 55-70 years with and without knee osteoarthritis. The main questions this trial aims to answer are:
* Does fatigue increase the risk of tripping while walking? and
* Does fatigue increase the risk of falling in response to a trip while walking? Participants will
* Complete questionnaires
* Wear a device that measures physical activity for 5-7 days
* Complete a 30 minute walk on a treadmill
* Complete the following before and after the treadmill walk:
* Computer test to measure mental fatigue
* Maximal strength testing
* Balance test
Researchers will compare adults with and without knee osteoarthritis to see if fall risk in adults with knee osteoarthritis is affected more by walking activity compared to adults without knee osteoarthritis.
Do I need to stop taking my current medications to join the trial?
Yes, you may need to stop taking certain medications. The trial excludes participants who use beta blockers or other medications that affect fatigue and balance.
What data supports the idea that Treadmill Walking for Knee Osteoarthritis is an effective treatment?
The available research shows that walking for exercise, including treadmill walking, can help manage knee osteoarthritis. One study found that walking can slow down the progression of symptoms and structural changes in the knee. Another study highlights that exercise, in general, is a well-known and effective way to manage symptoms of knee osteoarthritis. While the research does not directly compare treadmill walking to other treatments, it supports the idea that exercise, including walking, is beneficial for people with this condition.
12345What safety data exists for treadmill walking as a treatment for knee osteoarthritis?
Exercise, including treadmill walking, is considered a safe intervention for patients with knee osteoarthritis, with few contraindications or adverse events. Studies indicate that exercise interventions are safe and improve function through muscle strength and coordination, unlike NSAIDs which may have side effects. Both aerobic and strengthening exercises, such as treadmill walking, are effective for pain and function improvement in osteoarthritis patients.
678910Is a 30-minute treadmill walk a promising treatment for knee osteoarthritis?
Yes, a 30-minute treadmill walk is a promising treatment for knee osteoarthritis. Walking for exercise can help reduce pain and improve walking ability. It also supports overall health by enhancing muscle strength and joint movement, which can lead to less pain and better daily function.
34111213Eligibility Criteria
This trial is for adults aged 55-70 who sometimes to often feel knee pain, mainly on the inside of the knee joint, with little morning stiffness. They should be able to walk for half an hour without help like a cane or walker.Inclusion Criteria
I often have knee pain, mostly on the inner side, with little morning stiffness.
I can walk for 30 minutes without help.
Exclusion Criteria
I am taking beta blockers or medications that can cause tiredness.
History of joint replacement
I have heart or lung conditions that limit my daily activities.
+11 more
Participant Groups
Researchers are testing how tiredness from walking might increase tripping and falling risks in people with and without knee osteoarthritis. Participants will fill out surveys, wear an activity tracker for up to a week, do a treadmill walk, and take tests before and after walking to measure fatigue's effects.
2Treatment groups
Experimental Treatment
Group I: Knee osteoarthritisExperimental Treatment1 Intervention
Group II: HealthyExperimental Treatment1 Intervention
Find a Clinic Near You
Research Locations NearbySelect from list below to view details:
University of DelawareNewark, DE
Loading ...
Who Is Running the Clinical Trial?
University of DelawareLead Sponsor
National Institute of General Medical Sciences (NIGMS)Collaborator
References
Web-based therapeutic exercise resource center as a treatment for knee osteoarthritis: a prospective cohort pilot study. [2022]Although beneficial effects of exercise in the management of knee osteoarthritis (OA) have been established, only 14 -18% of patients with knee OA receive an exercise from their primary care provider. Patients with knee OA cite lack of physician exercise advice as a major reason why they do not exercise to improve their condition. The purpose of this pilot study was to investigate use of a web-based Therapeutic Exercise Resource Center (TERC) as a tool to prescribe strength, flexibility and aerobic exercise as part of knee OA treatment. It was hypothesized that significant change in clinical outcome scores would result from patients' use of the TERC.
Assessment of the content reporting for therapeutic exercise interventions among existing randomized controlled trials on knee osteoarthritis. [2019]Purpose/Rationale: Physical exercise interventions for the management of knee osteoarthritis are well known to be effective and accessible forms of rehabilitation and symptom management. However, without adequate reporting of these interventions, accurate replication and clinical use is negatively impacted.
Association Between Walking for Exercise and Symptomatic and Structural Progression in Individuals With Knee Osteoarthritis: Data From the Osteoarthritis Initiative Cohort. [2023]To assess the relationship between walking for exercise and symptomatic and structural disease progression in individuals with knee osteoarthritis (OA).
The influence of continuous versus interval walking exercise on knee joint loading and pain in patients with knee osteoarthritis. [2018]To evaluate whether knee contact force and knee pain are different between continuous and interval walking exercise in patients with knee osteoarthritis (OA).
Is exercise effective treatment for osteoarthritis of the knee? [2019]To review and determine the effectiveness of exercise treatment in osteoarthritis of the knee.
Diet and exercise for obese adults with knee osteoarthritis. [2022]Osteoarthritis (OA) is a common chronic disease and there is a need for treatments that can be provided for the course of the disease with minimal adverse side effects. Exercise is a safe intervention in patients with knee OA with few contraindications or adverse events. Obesity is the most modifiable risk factor for knee OA. The mechanisms by which obesity affects OA are of great concern to researchers and clinicians who manage this disease. This article reviews the physiologic and mechanical consequences of obesity and exercise on older adults with knee OA, the effects of long-term weight loss and exercise interventions, and the utility and feasibility of translating these results to clinical practice.
Is four-week underwater treadmill exercise regimen compared to home exercise efficacious for pain relief and functional improvement in obese patients with knee osteoarthritis? A randomized controlled trial. [2019]To investigate the efficacy of a four-week underwater treadmill exercise regimen compared to a home exercise regimen relative to pain relief and functional improvement in obese patients with knee osteoarthritis.
Exercise and weight loss in obese older adults with knee osteoarthritis: a preliminary study. [2022]The purposes of this pilot study were to determine if a combined dietary and exercise intervention would result in significant weight loss in older obese adults with knee osteoarthritis, and to compare the effects of exercise plus dietary therapy with exercise alone on gait, strength, knee pain, biomarkers of cartilage degradation, and physical function.
Does stride length influence metabolic cost and biomechanical risk factors for knee osteoarthritis in obese women? [2022]Obesity is the primary modifiable risk factor for knee osteoarthritis. The goal of this study was to develop a walking protocol for obese individuals that supported weight loss while minimizing biomechanical risk factors for knee osteoarthritis. We tested the hypotheses that walking with short, quick strides at a preferred walking speed requires more energy expenditure in obese women and reduces biomechanical risk factors for knee osteoarthritis at foot-ground impact relative to walking at the preferred stride length.
Effectiveness and safety of strengthening, aerobic, and coordination exercises for patients with osteoarthritis. [2022]Exercise has generated interest as an important nonpharmacological treatment for symptomatic osteoarthritis (OA) of the hip and knee. Effect sizes in exercise interventions are small to moderate for pain and functional improvements and are similar to those observed for improvement in pain for nonsteroidal anti-inflammatory drugs (NSAIDS). However, in contrast to NSAIDS, exercise interventions are safe and improve function through a direct effect on muscle strength and function. Both aerobic and strengthening exercises seem to be equally effective in regard to pain and function in patients with OA. In obese patients with OA, a combination of diet and exercise may be advantageous for optimal benefits in health-related quality-of-life and physical function. This article will focus on recent (September 2001-August 2002) randomized controlled trials with exercise as an intervention in patients with OA.
The Validity, Reliability, Measurement Error, and Minimum Detectable Change of the 30-Second Fast-Paced Walk Test in Persons with Knee Osteoarthritis: A Novel Test of Short-Distance Walking Ability. [2022]To develop and establish the reliability, validity, measurement error, and minimum detectable change of a novel 30-second fast-paced walk test (30SFW) in persons with knee osteoarthritis (OA) that is easy to administer and can quantify walking performance in persons of all abilities.
Physical and psychological correlates of disability among a cohort of individuals with knee osteoarthritis. [2015]While the physical correlates of knee osteoarthritis are well documented, less well documented are aspects of psychological functioning that may affect overall health and functional status. This paper describes the findings of a cross-sectional analysis that examined the strength of the relationship between selected psychological factors and the walking ability of adults with knee joint osteoarthritis. The variables assessed were pain, depression, levels of self-efficacy for pain and other-symptoms management, walking endurance, walking speed, and perceived exertion when walking. The sample, including 57 persons with unilateral and 43 persons with bilateral radiographic and symptomatic knee osteoarthritis, mean age, 69.9 +/- 1 years, underwent standard assessment procedures on a single test occasion using several validated questionnaires and a series of walking tests on level ground. Bivariate and multiple regression analyses revealed that (a) higher pain and other-symptoms self-efficacy scores were associated with lower levels of pain ( r = -0.29, -0.20.), perceived exertion during a walking task ( r = -0.29, -0.31), and depression scores ( r = -0.46, -0.54) ( p
[Exercise therapy in hip or knee osteoarthritis]. [2011]"Exercise is medicine": exercise therapy reduces pain and activity limitations in osteoarthritis of the knee and is likely to have the same effects in osteoarthritis of the hip. Further research into exercise therapy is needed, since disease-modifying drugs are not available, pain medication can cause side effects, and surgical interventions are preferably applied in an advanced stage of disease. Classical exercise therapy is aimed at improving muscle strength, aerobic capacity, range of joint motion, and training of walking and activities of daily living. New modalities of targeted exercise therapy are currently being developed, aimed at the correction of low levels of activity and to correct instability of the knee. Weight loss, preferably combined with exercise therapy, reduces pain and activity limitations in osteoarthritis patients who are overweight. Modalities of exercise therapy adapted to comorbid conditions are currently being developed.