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What is Carbidopa
CarbidopaThe Generic name of this drug
Treatment SummaryA clinical trial is being conducted to test the safety and tolerability of Foscarbidopa, a drug used to treat Parkinson's disease. The trial will involve 24-hour daily exposure to continuous subcutaneous infusion of ABBV-951 in adult participants with Parkinson's disease.
Sinemetis the brand name
Carbidopa Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Sinemet
Carbidopa
1975
299
Approved as Treatment by the FDA
Carbidopa, also called Sinemet, is approved by the FDA for 8 uses which include Parkinson's Disease (PD) and Parkinsonism post encephalitic .Parkinson's Disease (PD)
Used to treat Parkinson's Disease (PD) in combination with Levodopa
Parkinsonism post encephalitic
Used to treat Parkinsonism post encephalitic in combination with Levodopa
manganese intoxication
Used to treat manganese intoxication in combination with Levodopa
carbon monoxide intoxication
Used to treat carbon monoxide intoxication in combination with Levodopa
levodopa-driven nausea and vomiting
Parkinson's Disease
Used to treat Parkinson's Disease (PD) in combination with Levodopa
Carbon Monoxide Poisoning
Used to treat carbon monoxide intoxication in combination with Levodopa
Parkinson Disease
Used to treat Symptomatic Parkinson Disease in combination with Levodopa
When to interrupt dosage
The ideal measure of Carbidopa relies upon the diagnosed condition. The dosage fluctuates based on the administration approach featured in the table below.Condition
Dosage
Administration
manganese intoxication
10.0 mg, 25.0 mg, , 50.0 mg, 31.25 mg, 37.5 mg, 12.5 mg, 18.75 mg, 23.75 mg, 48.75 mg, 61.25 mg, 36.25 mg, 4.63 mg/mL, 43.75 mg, 5.0 mg/mL
, Oral, Tablet, Tablet - Oral, Tablet, extended release, Tablet, extended release - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Enteral, Gel, Gel - Enteral, Capsule, extended release, Capsule, extended release - Oral, Suspension, Suspension - Enteral
Carbon Monoxide Poisoning
10.0 mg, 25.0 mg, , 50.0 mg, 31.25 mg, 37.5 mg, 12.5 mg, 18.75 mg, 23.75 mg, 48.75 mg, 61.25 mg, 36.25 mg, 4.63 mg/mL, 43.75 mg, 5.0 mg/mL
, Oral, Tablet, Tablet - Oral, Tablet, extended release, Tablet, extended release - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Enteral, Gel, Gel - Enteral, Capsule, extended release, Capsule, extended release - Oral, Suspension, Suspension - Enteral
Parkinson's Disease
10.0 mg, 25.0 mg, , 50.0 mg, 31.25 mg, 37.5 mg, 12.5 mg, 18.75 mg, 23.75 mg, 48.75 mg, 61.25 mg, 36.25 mg, 4.63 mg/mL, 43.75 mg, 5.0 mg/mL
, Oral, Tablet, Tablet - Oral, Tablet, extended release, Tablet, extended release - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Enteral, Gel, Gel - Enteral, Capsule, extended release, Capsule, extended release - Oral, Suspension, Suspension - Enteral
Parkinson Disease
10.0 mg, 25.0 mg, , 50.0 mg, 31.25 mg, 37.5 mg, 12.5 mg, 18.75 mg, 23.75 mg, 48.75 mg, 61.25 mg, 36.25 mg, 4.63 mg/mL, 43.75 mg, 5.0 mg/mL
, Oral, Tablet, Tablet - Oral, Tablet, extended release, Tablet, extended release - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Enteral, Gel, Gel - Enteral, Capsule, extended release, Capsule, extended release - Oral, Suspension, Suspension - Enteral
levodopa-driven nausea and vomiting
10.0 mg, 25.0 mg, , 50.0 mg, 31.25 mg, 37.5 mg, 12.5 mg, 18.75 mg, 23.75 mg, 48.75 mg, 61.25 mg, 36.25 mg, 4.63 mg/mL, 43.75 mg, 5.0 mg/mL
, Oral, Tablet, Tablet - Oral, Tablet, extended release, Tablet, extended release - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Enteral, Gel, Gel - Enteral, Capsule, extended release, Capsule, extended release - Oral, Suspension, Suspension - Enteral
Parkinsonism post encephalitic
10.0 mg, 25.0 mg, , 50.0 mg, 31.25 mg, 37.5 mg, 12.5 mg, 18.75 mg, 23.75 mg, 48.75 mg, 61.25 mg, 36.25 mg, 4.63 mg/mL, 43.75 mg, 5.0 mg/mL
, Oral, Tablet, Tablet - Oral, Tablet, extended release, Tablet, extended release - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Enteral, Gel, Gel - Enteral, Capsule, extended release, Capsule, extended release - Oral, Suspension, Suspension - Enteral
Warnings
Carbidopa ContraindicationsCondition
Risk Level
Notes
Pulse Frequency
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Carbidopa may interact with Pulse Frequency
Common Carbidopa Drug Interactions
Drug Name
Risk Level
Description
Abacavir
Minor
Carbidopa may decrease the excretion rate of Abacavir which could result in a higher serum level.
Acetaminophen
Minor
Carbidopa may decrease the excretion rate of Acetaminophen which could result in a higher serum level.
Aclidinium
Minor
Carbidopa may decrease the excretion rate of Aclidinium which could result in a higher serum level.
Acrivastine
Minor
Carbidopa may decrease the excretion rate of Acrivastine which could result in a higher serum level.
Albutrepenonacog alfa
Minor
Carbidopa may decrease the excretion rate of Albutrepenonacog alfa which could result in a higher serum level.
Carbidopa Novel Uses: Which Conditions Have a Clinical Trial Featuring Carbidopa?
No active clinical trials are currently exploring the utilization of Carbidopa for undefined conditions.Condition
Clinical Trials
Trial Phases
Parkinson's Disease
37 Actively Recruiting
Not Applicable, Phase 1, Phase 4, Phase 2, Phase 3, Early Phase 1
Parkinson Disease
0 Actively Recruiting
Carbon Monoxide Poisoning
0 Actively Recruiting
Parkinsonism post encephalitic
0 Actively Recruiting
manganese intoxication
0 Actively Recruiting
levodopa-driven nausea and vomiting
0 Actively Recruiting
Carbidopa Reviews: What are patients saying about Carbidopa?
5Patient Review
7/2/2014 Before I was diagnosed, I felt awful-- like I was much older than my 51 years. Shuffling, tremors, loss of balance, incontinence, and constant fatigue were only some of the problems I faced on a daily basis. But after starting this medication regimen, it honestly felt like a miracle. Most of my symptoms have disappeared and while I still get tired easily, it's mostly because now that I feel better overall I push myself to do more.
5Patient Review
4/1/2016 This drug is effective in helping me to fall asleep when my legs are hurting from sitting for long periods of time.
5Patient Review
7/2/2014 At 51, I felt like an old woman before starting this medication. I had tremors, balance issues, incontinence, and constant pain and fatigue. These meds were a godsend-- they helped me recover most of my quality of life.
5Patient Review
4/1/2016 This medication is a godsend. I was dealing with serious pain and discomfort that made it impossible to sleep, but this allowed me to finally get some rest.
5Patient Review
4/1/2016 This drug has helped me to manage my chronic pain and get some much needed rest.
Patient Q&A Section about carbidopa
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.What is the drug carbidopa used for?
"Carbidopa and levodopa combination is used to treat Parkinson's disease, a disorder of the central nervous system."
Answered by AI
What does carbidopa do for Parkinson's?
"Israel said researchers have found that levodopa, the most common treatment for [Parkinson's disease](https://www.withpower.com/clinical-trials/parkinson's-disease), may cause the very same symptoms it is meant to relieve.
According to Israel, researchers have found that levodopa, the most common treatment for Parkinson's disease, may cause the very same symptoms it is meant to relieve."
Answered by AI
What are the long term side effects of carbidopa levodopa?
"Sinemet is the most effective medicine, but it is associated with high risks of long-term side effects. Levodopa is less effective but causes fewer side effects."
Answered by AI
When should I take carbidopa?
"This medication is to be taken by mouth, with or without food, as directed by a doctor. It should be taken 4 to 8 hours apart, while awake. The doses should not be crushed or chewed, as this could release all of the drug at once and increase the risk of experiencing side effects."
Answered by AI