← Back to Search

Other

Topical Oils for Wrinkles

N/A
Recruiting
Research Sponsored by Integrative Skin Science and Research
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Post-menopausal women of Fitzpatrick skin types 1, 2, and 3
Be older than 18 years old
Must not have
Adults unable to consent
Those with an autoimmune photosensitive condition or a known genetic condition with a deficiency in collagen production (such as Ehlers-Danlos syndromes)
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 16 weeks
Awards & highlights

Summary

This trial will look at how using almond oil, almond oil with vitamin E, tretinoin oil with castor oil on the face affects fine lines, wrinkles, pigmentation, hydration, water

Who is the study for?
This trial is for individuals with facial wrinkles, pigmentation issues, or dry skin. It's also relevant for those with Ehlers-Danlos Syndrome and collagen degeneration. Participants should be interested in testing topical treatments to improve skin appearance.
What is being tested?
The study tests the effects of three topical products: almond oil alone, almond oil with added Vitamin E, and tretinoin oil mixed with castor oil on facial wrinkles and other skin conditions like pigmentation and dryness.
What are the potential side effects?
Potential side effects may include skin irritation, redness from the tretinoin (a form of vitamin A), increased sensitivity to sunlight, peeling or dryness especially where the product is applied.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
I am a post-menopausal woman with fair to olive skin.

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:
Select...
I am unable to give consent for medical procedures.
Select...
I have a condition that affects my skin's reaction to sunlight or affects collagen production.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~16 weeks
This trial's timeline: 3 weeks for screening, Varies for treatment, and 16 weeks for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Facial wrinkles
Secondary study objectives
Changes in Pigment intensity through the use of high resolution photography (BTBP Clarity Pro)
Changes in skin hydration
Pigment intensity measured through SkinColorCatch.
+3 more

Trial Design

3Treatment groups
Experimental Treatment
Group I: Almond oil augmented with 0.5% Vitamin EExperimental Treatment1 Intervention
Almond oil augmented with 0.5% Vitamin E. 1-2 Drops of randomized topical product will be applied on entire face nightly. Duration: 16 weeks
Group II: Almond OilExperimental Treatment1 Intervention
Almond Oil. 1-2 Drops of randomized topical product will be applied on entire face nightly. Duration: 16 weeks
Group III: 0.025% Tretinoin oil augmented with castor oilExperimental Treatment1 Intervention
0.025% Tretinoin oil augmented with castor oil. 1-2 Drops of randomized topical product will be applied on entire face nightly. Duration: 16 weeks

Find a Location

Who is running the clinical trial?

Integrative Skin Science and ResearchLead Sponsor
32 Previous Clinical Trials
1,884 Total Patients Enrolled
1 Trials studying Pigmentation
60 Patients Enrolled for Pigmentation
~60 spots leftby Jan 2025
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Back to top