Low-Dose CT Screening for Lung Cancer
(ILST Trial)

Recruiting in Palo Alto (17 mi)

+5 other locations

Overseen bySteven Lam

Age: 18+

Sex: Any

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Academic

Waitlist Available

Sponsor: The University of Queensland

No Placebo Group

Trial Summary

What is the purpose of this trial?

People who may be at increased risk of lung cancer due to age and smoking history will be invited to participate in this international study to determine the best way of using computed tomography (CT) of the chest to screen for early lung cancer. Overseas data show that CT screening (screening tests can find diseases early, when they're easier to treat) can reduce deaths from lung cancer and this study will help determine who is most likely benefit from screening.

Research Team

Kwun M Fong

Principal Investigator

UQTRC at TPCH

Steven Lam

Principal Investigator

British Columbia Cancer Agency

Eligibility Criteria

This trial is for men and women aged 55-80 who are current or former smokers with a significant history of smoking (at least 30 pack-years) and an elevated risk of lung cancer. They must be able to undergo CT scans, have not had chest CTs in the past two years, no recent chemotherapy, and cannot have been previously diagnosed with lung cancer.

Inclusion Criteria

I am between 55 and 80 years old.

Capable of providing informed consent for screening procedures (low dose spiral CT)

I am currently smoking or have quit smoking for at least a year.

See 2 more

Exclusion Criteria

Unwilling to sign a consent

I have symptoms like coughing up blood, chest pain, or losing weight unexpectedly.

I have cancer outside the lung that was not treated to cure.

See 9 more

Treatment Details

Interventions

Low dose CT (Diagnostic Test)

Trial OverviewThe ILST is testing whether low-dose CT scans can effectively screen for early lung cancer in individuals at high risk due to their age and smoking history. The goal is to see if this screening method can reduce deaths from lung cancer by catching it earlier.

Participant Groups

1Treatment groups

Experimental Treatment

Group I: SingleExperimental Treatment1 Intervention

Single arm only, CT screening of lung