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Linoleic Acid-Rich Oil for Sarcopenia

N/A
Waitlist Available
Led By Martha Belury, PhD RDN
Research Sponsored by Ohio State University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up week 0 and week 24

Summary

This trial will study how daily consumption of linoleic acid-rich oil affects muscle strength, volume, fatigue resistance, and mobility in older adults.

Who is the study for?
This trial is for older adults with sarcopenia, which means they have lost muscle strength and mass. Participants will need to consume oil daily as part of the study.
What is being tested?
The FORCES Study is testing if eating foods high in linoleic acid or oleic acid can improve muscle strength, size, endurance, and mobility in older people with weakened muscles.
What are the potential side effects?
Potential side effects from consuming these oils may include gastrointestinal discomfort or allergic reactions but are generally considered low risk.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~week 0 and week 24
This trial's timeline: 3 weeks for screening, Varies for treatment, and week 0 and week 24 for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Changes is leg extensor muscle strength
Secondary study objectives
Change in leg fatiguability
Change in maximum leg press strength
Change in muscle mitochondria function
+8 more
Other study objectives
Association of changes 4-LA-cardiolipin with muscle function
Association of changes 4-LA-cardiolipin with muscle strength
Association of changes 4-LA-cardiolipin with muscle volume
+6 more

Trial Design

2Treatment groups
Experimental Treatment
Placebo Group
Group I: High Linoleic Safflower OilExperimental Treatment1 Intervention
consumption of 12g of high linoleic safflower oil every day
Group II: High Oleic Safflower OilPlacebo Group1 Intervention
Consumption of 12g of high oleic safflower oil every day

Find a Location

Who is running the clinical trial?

Ohio State UniversityLead Sponsor
871 Previous Clinical Trials
655,666 Total Patients Enrolled
1 Trials studying Sarcopenia
19 Patients Enrolled for Sarcopenia
National Institutes of Health (NIH)NIH
2,840 Previous Clinical Trials
8,172,557 Total Patients Enrolled
3 Trials studying Sarcopenia
95 Patients Enrolled for Sarcopenia
Martha Belury, PhD RDNPrincipal InvestigatorOhio State University
~44 spots leftby May 2029
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