← Back to Search

Alcohol's Impact on Decision-Making in PTSD (PACS Trial)

N/A
Recruiting
Led By Elizabeth Lippard, PhD
Research Sponsored by University of Texas at Austin
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 1 year

Summary

This trial will investigate how PTSD increases risk for AUDs, and how alcohol may alter decision-making in PTSD, to inform interventions & prevention efforts.

Who is the study for?
This trial is for adults aged 21-60 with PTSD who have had at least two occasions in the past year where they consumed a significant amount of alcohol (4 drinks for men, 3 for women). They must be diagnosed with PTSD through an interview.
What is being tested?
The study examines how acute alcohol consumption affects decision-making related to approach-avoidance conflict in individuals with PTSD. It involves controlled administration of alcohol and placebo, along with neuroimaging and computational analysis.
What are the potential side effects?
Possible side effects include typical reactions to alcohol such as impaired judgment, dizziness, nausea, or more severe responses if participants have unusual sensitivity to alcohol.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~1 year
This trial's timeline: 3 weeks for screening, Varies for treatment, and 1 year for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Relations between changes in dorsal anterior cingulate cortex activation with alcohol use over a one-year follow-up
Relations between ratio of approach to avoidance choices with alcohol use over a one-year follow-up
changes in dorsal anterior cingulate cortex activation
+1 more

Trial Design

2Treatment groups
Active Control
Placebo Group
Group I: AlcoholActive Control1 Intervention
Participants will drink beverages containing alcohol.
Group II: PlaceboPlacebo Group1 Intervention
Participants will drink beverages containing a very low dose of alcohol (placebo condition).

Find a Location

Who is running the clinical trial?

University of Texas at AustinLead Sponsor
378 Previous Clinical Trials
86,409 Total Patients Enrolled
Elizabeth Lippard, PhDPrincipal InvestigatorUniversity of Texas at Austin
3 Previous Clinical Trials
228 Total Patients Enrolled
Josh Cisler, PhDPrincipal InvestigatorUniversity of Texas at Austin
1 Previous Clinical Trials
35 Total Patients Enrolled
~133 spots leftby May 2028
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Back to top