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Charlottesville Medical Research
Claim this profileCharlottesville, Virginia 22911
Global Leader in Migraine
Global Leader in Osteoarthritis
Conducts research for Crohn's Disease
Conducts research for Obesity
Conducts research for Colorectal Cancer
115 reported clinical trials
2 medical researchers
Summary
Charlottesville Medical Research is a medical facility located in Charlottesville, Virginia. This center is recognized for care of Migraine, Osteoarthritis, Crohn's Disease, Obesity, Colorectal Cancer and other specialties. Charlottesville Medical Research is involved with conducting 115 clinical trials across 89 conditions. There are 2 research doctors associated with this hospital, such as James Clark and Daniel Pambianco, MD.Top PIs
James ClarkCharlottesville Medical Research3 years of reported clinical research
Studies Diabetes
Studies Type 2 Diabetes
10 reported clinical trials
15 drugs studied
Daniel Pambianco, MDCharlottesville Medical Research5 years of reported clinical research
Studies Colorectal Cancer
Studies Peptic Esophagitis
2 reported clinical trials
3 drugs studied
Clinical Trials running at Charlottesville Medical Research
Migraine
Type 2 Diabetes
Obesity
High Cholesterol
Flu
Hardening of the Arteries
Gastroenteritis
Norovirus
Stomach Flu
Urinary Tract Infection
Ubrogepant
for Migraine
A migraine is a moderate to severe headache typically on one side of the head. A migraine attack is a headache that may be accompanied by throbbing, nausea, vomiting, sensitivity to light and sound, or other symptoms. Menstrual migraine (MM) is defined as migraine attacks that occur within the perimenstrual period (PMP) in at least 2 out of 3 menstrual cycles. The PMP is from 2 days before the onset of menstrual bleeding to 2 days after. This study will assess how safe and effective ubrogepant is in treating menstrual migraine. Adverse Events and change in disease activity will be assessed. Ubrogepant is an investigational drug being developed for short-term prevention of menstrual migraine. Participants will be randomly assigned to one of the 2 groups to receive either ubrogepant or placebo. Around 450 adult female participants with menstrual migraine will be enrolled in approximately 85 sites in the United States and Puerto Rico. Participants will receive oral ubrogepant tablets once daily for 7 consecutive days starting 3 days prior to estimated onset of menses per cycle for 3 PMPs during double-blind period (16 weeks). Eligible participants may continue to receive oral ubrogepant tablets once daily for 7 consecutive days per cycle starting 3 days prior to estimated onset of menses during open-label extension period (52 weeks). There may be higher treatment burden for participants in this trial compared to their standard of care. Participants will collect data daily in electronic diaries and attend regular visits during the study at a hospital or clinic. The effect of the treatment will be checked by medical assessments, blood tests, checking for side effects and completing questionnaires.
Recruiting1 award Phase 33 criteria
BOTOX Injections
for Migraine
This trial is testing BOTOX injections to prevent migraines in adults who have episodic migraines. BOTOX helps by blocking pain signals in the nerves, reducing migraine frequency and severity. Participants will receive injections and be monitored through periodic medical visits. Botox has been studied for more than a decade as a migraine preventative.
Recruiting1 award Phase 34 criteria
BHV-2100
for Migraine
This study is designed to identify at least one dose of BHV-2100 that is safe and effective in reducing headache pain and other symptoms in the treatment of migraine.
Recruiting0 awards Phase 22 criteria
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Frequently asked questions
What kind of research happens at Charlottesville Medical Research?
Charlottesville Medical Research is a medical facility located in Charlottesville, Virginia. This center is recognized for care of Migraine, Osteoarthritis, Crohn's Disease, Obesity, Colorectal Cancer and other specialties. Charlottesville Medical Research is involved with conducting 115 clinical trials across 89 conditions. There are 2 research doctors associated with this hospital, such as James Clark and Daniel Pambianco, MD.