Popular Trials
Antibiotic
Microbiota Transfer Therapy for Autism and Gastrointestinal Issues
This trial tests a treatment called Microbiota Transfer Therapy (MTT) for children with Autism Spectrum Disorder and gut problems. It uses antibiotics to clear bad bacteria, cleans the bowel, and then adds good bacteria from donor stool over a few months. The goal is to see if this helps improve their symptoms. Microbiota Transfer Therapy (MTT) has shown significant improvements in gastrointestinal and autism symptoms in previous studies, with benefits persisting for some time after treatment.
Dual Orexin Receptor Antagonist
Suvorexant for Sleep Issues in Children with Autism
This trial is testing suvorexant, a sleep aid, in children and adolescents with Autism Spectrum Disorder who have sleep problems. Suvorexant helps people fall asleep and stay asleep by blocking wakefulness signals in the brain.
GABAa Receptor Agonist
Zolpidem for Sleep Disturbances in Children with Autism
This trial is testing zolpidem, a medication that helps people fall asleep, in children and adolescents with Autism Spectrum Disorder (ASD). These children often have trouble sleeping, and typical treatments may not work for them. Zolpidem works by calming the brain, making it easier to fall asleep. Zolpidem is a medication commonly used to treat sleep problems by helping people fall asleep, and it has been studied in various populations including healthy adults and those with insomnia.
Popular Filters
Trials for Autism Spectrum Disorder Patients
Atypical Antipsychotic
Cariprazine for Autism Spectrum Disorder
This trial is testing a new drug called cariprazine to see if it can help reduce irritability in children and teenagers with autism. The study involves taking the drug daily for a period of time and includes regular check-ups to monitor safety and effectiveness. The goal is to find out if cariprazine can improve behavior in young people with autism. Cariprazine has shown potential in alleviating core behavioral deficits and hyperactivity in animal models of autism spectrum disorder.
Behavioral Intervention
Behavioral Therapy for Autism
This trial tests a new therapy called BTIA, which helps teens with autism manage their emotions and behaviors. The therapy involves regular sessions where therapists teach both the teens and their parents how to handle frustration and improve daily functioning. The study aims to see if BTIA can reduce disruptive behaviors and help these teens function better in their everyday lives.
Behavioral Intervention
SENSE Theatre for Autism
This trial tests SENSE Theatre®, a program that uses acting to help adults with autism improve their social skills. It focuses on practicing face recognition and social interactions through repeated role-playing activities. The goal is to see if these improvements last. SENSE Theatre® is a novel intervention that combines trained peers to facilitate performance-based theatrical treatment in a supportive, community-based environment.
Behavioural Intervention
Adaptive Autism Intervention for Toddlers with Autism
This trial tests a program to help toddlers with autism improve their social and communication skills. The program starts with play-based activities and is adjusted based on each child's progress. These activities have been shown to improve social communication in young children with autism. The goal is to find the best way to support these children in everyday settings.
Trials for Asperger Syndrome Patients
Atypical Antipsychotic
Cariprazine for Autism Spectrum Disorder
This trial is testing a new drug called cariprazine to see if it can help reduce irritability in children and teenagers with autism. The study involves taking the drug daily for a period of time and includes regular check-ups to monitor safety and effectiveness. The goal is to find out if cariprazine can improve behavior in young people with autism. Cariprazine has shown potential in alleviating core behavioral deficits and hyperactivity in animal models of autism spectrum disorder.
Behavioral Intervention
Behavioral Therapy for Autism
This trial tests a new therapy called BTIA, which helps teens with autism manage their emotions and behaviors. The therapy involves regular sessions where therapists teach both the teens and their parents how to handle frustration and improve daily functioning. The study aims to see if BTIA can reduce disruptive behaviors and help these teens function better in their everyday lives.
Behavioral Intervention
SENSE Theatre for Autism
This trial tests SENSE Theatre®, a program that uses acting to help adults with autism improve their social skills. It focuses on practicing face recognition and social interactions through repeated role-playing activities. The goal is to see if these improvements last. SENSE Theatre® is a novel intervention that combines trained peers to facilitate performance-based theatrical treatment in a supportive, community-based environment.
Behavioural Intervention
Adaptive Autism Intervention for Toddlers with Autism
This trial tests a program to help toddlers with autism improve their social and communication skills. The program starts with play-based activities and is adjusted based on each child's progress. These activities have been shown to improve social communication in young children with autism. The goal is to find the best way to support these children in everyday settings.
Phase 3 Trials
Atypical Antipsychotic
Cariprazine for Autism Spectrum Disorder
This trial is testing a new drug called cariprazine to see if it can help reduce irritability in children and teenagers with autism. The study involves taking the drug daily for a period of time and includes regular check-ups to monitor safety and effectiveness. The goal is to find out if cariprazine can improve behavior in young people with autism. Cariprazine has shown potential in alleviating core behavioral deficits and hyperactivity in animal models of autism spectrum disorder.
Atypical Antipsychotic
Cariprazine for Pediatric Schizophrenia
This trial is testing the safety and effectiveness of cariprazine in children and teens with schizophrenia, bipolar I disorder, or autism. The goal is to see if the medication is safe and beneficial for use in these young patients.
Cannabinoid
Cannabidiol for Autism
This trial is testing whether a medicine called cannabidiol (CBD) can help boys aged 7-14 with autism who have severe behavior problems. CBD, which comes from the cannabis plant but doesn't make you feel 'high,' might help by calming brain activity. The goal is to see if this treatment can improve their behavior and quality of life. Cannabidiol (CBD) has been reported to be safe and well-tolerated and has shown potential in managing symptoms of autism.
Serotonin Inverse Agonist
Pimavanserin for Autism Spectrum Disorder
This trial is testing pimavanserin, a medication that may help reduce irritability, agitation, and self-harm in young individuals with autism. The study focuses on those who struggle with these challenging behaviors. Pimavanserin works by balancing brain chemicals to improve mood and behavior.
Trials With No Placebo
Behavioral Intervention
Behavioral Therapy for Autism
This trial tests a new therapy called BTIA, which helps teens with autism manage their emotions and behaviors. The therapy involves regular sessions where therapists teach both the teens and their parents how to handle frustration and improve daily functioning. The study aims to see if BTIA can reduce disruptive behaviors and help these teens function better in their everyday lives.
Behavioral Intervention
SENSE Theatre for Autism
This trial tests SENSE Theatre®, a program that uses acting to help adults with autism improve their social skills. It focuses on practicing face recognition and social interactions through repeated role-playing activities. The goal is to see if these improvements last. SENSE Theatre® is a novel intervention that combines trained peers to facilitate performance-based theatrical treatment in a supportive, community-based environment.
Behavioural Intervention
Adaptive Autism Intervention for Toddlers with Autism
This trial tests a program to help toddlers with autism improve their social and communication skills. The program starts with play-based activities and is adjusted based on each child's progress. These activities have been shown to improve social communication in young children with autism. The goal is to find the best way to support these children in everyday settings.
Behavioral Intervention
JASPER Intervention for Autism
This trial is testing JASPER, a play-based therapy, on young children with autism who have limited verbal skills. The therapy uses guided play to help these children improve their social and communication abilities. JASPER (Joint Attention, Symbolic Play, Engagement, and Regulation) is a naturalistic developmental behavioral intervention that has been found effective for promoting social communication in young children with autism.
Behavioral Intervention
DTT + JASPER for Autism
This trial aims to improve language skills in preschool children with autism using a structured teaching and social interaction-based learning program. The program is adjusted based on each child's progress. The goal is to help these children develop better communication skills and avoid being minimally verbal by age 6.
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Frequently Asked Questions
Introduction to autism
What are the top hospitals conducting autism research?
Autism, a complex neurological condition affecting individuals worldwide, is being met with dedicated research efforts at several prestigious hospitals. Stanford University in Stanford leads the way with seven ongoing clinical trials focused on autism. Located in the heart of Silicon Valley, this institution brings together cutting-edge technology and innovative thinking to tackle the challenges faced by individuals on the autism spectrum. Not far behind is Massachusetts General Hospital in Boston, which currently has five active autism trials underway. As one of the top-ranked hospitals in the United States, their commitment to understanding and addressing autism's complexities is evident.
Further south, Vanderbilt University Medical Center in Nashville joins this group with four ongoing autism trials. Known for its interdisciplinary approach to healthcare and research excellence, this center is committed to uncovering new insights into autism diagnosis and treatment options. Meanwhile, Yale Child Study Center in New Haven plays a vital role as well through their four active clinical trials aimed at improving our understanding of autism spectrum disorders and paving the way for more effective interventions.
On the West Coast, UCLA stands out among California's top institutions with four ongoing clinical trials focusing on Autism Spectrum Disorder (ASD). Situated amidst Los Angeles' vibrant academic community and diverse population base, UCLA researchers are exploring new avenues for early detection methods while enhancing therapeutic approaches tailored towards each individual’s unique needs.
While these hospitals have yet to conduct previous studies specifically related to autism, their current dedication substantiates their commitment towards unraveling mysteries surrounding this condition that affects millions globally. Through collaborative efforts across various disciplines including neuroscience, psychology,and genetics; these esteemed medical centers strive not only to improve quality-of-life but also foster an inclusive society where every person can thrive regardless of neurodiversity
Which are the best cities for autism clinical trials?
When it comes to autism clinical trials, several cities in the United States emerge as prominent hubs of research and development. In Houston, Texas, there are 10 active trials investigating treatments like GWP42003-P, ML-004 (IR)/(ER) tablet, and Cariprazine Flexible Dose. Stanford, California follows closely with 9 ongoing studies exploring interventions such as Zolpidem and a Mobile Game System for Potential Treatment of Developmental Delays. Phoenix, Arizona also boasts 9 active trials examining treatments like Levoleucovorin Calcium. These locations offer individuals with autism opportunities to participate in cutting-edge clinical trials aimed at advancing treatment options and improving their quality of life.
Which are the top treatments for autism being explored in clinical trials?
In the realm of autism treatment, clinical trials are paving the way for breakthroughs. One notable contender is cannabidivarin (CBDV), currently being explored in three ongoing trials. Another promising candidate is balovaptan, showing potential with two active clinical trials dedicated to autism research. Lastly, trofinetide stands out as a frontrunner, garnering attention through its involvement in multiple studies aiming to uncover effective treatments for individuals on the autism spectrum. As researchers delve deeper into these innovative therapies, hope continues to grow for improved outcomes and increased quality of life for those affected by autism.
What are the most recent clinical trials for autism?
Exciting advancements are being made in the field of autism research, with several recent clinical trials offering hope for improved treatments. These trials include a Phase 1 study investigating a new treatment for autism, as well as Phase 2 studies exploring the effectiveness of pimavanserin tartrate, zolpidem, suvorexant, and diphenhydramine in managing symptoms associated with autism. By evaluating these potential therapies, researchers aim to enhance our understanding of autism and develop more targeted approaches for individuals on the spectrum.
What autism clinical trials were recently completed?
Several clinical trials focusing on autism have recently concluded, representing significant progress in the field. These completed trials include a study investigating the effectiveness of a novel intervention for enhancing social communication skills in children with autism, led by researchers at Stanford University. In addition, a trial examining the impact of early intensive behavioral intervention on language development and adaptive behavior in toddlers with autism was successfully completed at Boston Children's Hospital. Furthermore, scientists from the University of California conducted a trial evaluating a new pharmacological treatment aimed at reducing repetitive behaviors associated with autism spectrum disorder. These recent advancements highlight ongoing efforts to explore innovative approaches for improving outcomes and quality of life for individuals with autism.