Device
Adaptive DBS for Obsessive-Compulsive Disorder
This trial is for people with OCD who have not responded to other treatments. The goal is to use signals from the brain to automatically adjust the Deep Brain Stimulation (DBS) stimulation factors to improve symptom management and reduce stimulation-induced behavioral side effects.
NMDA Receptor Antagonist
Ketamine for Obsessive-Compulsive Disorder
This trial aims to understand how ketamine quickly improves symptoms in people with Obsessive-Compulsive Disorder (OCD). Ketamine works by blocking a specific brain receptor, which helps reduce repetitive thoughts and behaviors. Recent research demonstrated that ketamine rapidly reduces OCD symptoms. The study focuses on how this process happens at different levels in the brain.
Behavioural Intervention
Brain Stimulation for Obsessive-Compulsive Disorder
This trial is looking for better ways to treat OCD by identifying abnormal brain signals associated with the disorder and psychiatric symptoms, and investigating whether novel therapeutic stimulation sites can help improve OCD symptoms.
Behavioural Intervention
Mindfulness-Based Interventions for Obsessive-Compulsive Disorder
This trial is testing a new treatment called Mindfulness-Based Cognitive Therapy (MBCT) for people with Obsessive-Compulsive Disorder (OCD) who haven't fully benefited from standard treatments. MBCT helps patients become more aware of their thoughts and feelings without reacting to them, which can reduce OCD symptoms. If successful, this approach could be used widely in clinical settings to help more people with OCD. Mindfulness-Based Cognitive Therapy (MBCT) has been shown to be effective in various mental disorders and is now being explored as a complementary treatment for OCD, particularly for those who do not fully benefit from standard treatments.
Behavioural Intervention
Dextromethorphan + Fluoxetine for Obsessive-Compulsive Disorder
This trial is testing if a common cough medicine can help when taken with a low dose of a usual obsessive-compulsive disorder (OCD) medication. It targets patients with OCD and related disorders who often do not get enough help from current treatments. The cough medicine might work with the usual drug to better control troubling thoughts and actions. The usual medication is a well-established treatment for obsessive-compulsive disorder and has been shown to be effective in multiple studies.
Procedure
Adaptive Deep Brain Stimulation for Obsessive-Compulsive Disorder
This trial is for participants that have been diagnosed with intractable Obsessive-compulsive disorder (OCD) and want to develop an adaptive Deep Brain Stimulation (aDBS) system.
Popular Filters
Trials for Obsessive-Compulsive Disorder Patients
Deep Brain Stimulation
Deep Brain Stimulation for Obsessive-Compulsive Disorder
This trial is for people with a hard-to-control form of OCD. The goal is to find a more reliable system for treating OCD by studying how to best place electrodes in the brain to deliver electrical stimulation.
Selective Serotonin Reuptake Inhibitor
Fluoxetine for Obsessive-Compulsive Disorder
This trial uses brain scans and fluoxetine to treat unmedicated OCD patients. It aims to see how the brain changes with treatment and identify markers that predict treatment success. Fluoxetine, a selective serotonin reuptake inhibitor (SSRI), has been used for many years to treat obsessive-compulsive disorder (OCD) and is recognized for its efficacy in reducing both obsessions and compulsions.
Inhaled Anesthetic
Nitrous Oxide for Obsessive-Compulsive Disorder
This trial uses nitrous oxide gas, commonly known as laughing gas, to see if it can quickly help people with OCD. It targets individuals with OCD because they often struggle with persistent and distressing thoughts and behaviors. The gas might work by altering brain chemicals to improve mood and reduce symptoms.
Trials for Hoarding Disorder Patients
Deep Brain Stimulation
Deep Brain Stimulation for Obsessive-Compulsive Disorder
This trial is for people with a hard-to-control form of OCD. The goal is to find a more reliable system for treating OCD by studying how to best place electrodes in the brain to deliver electrical stimulation.
Selective Serotonin Reuptake Inhibitor
Fluoxetine for Obsessive-Compulsive Disorder
This trial uses brain scans and fluoxetine to treat unmedicated OCD patients. It aims to see how the brain changes with treatment and identify markers that predict treatment success. Fluoxetine, a selective serotonin reuptake inhibitor (SSRI), has been used for many years to treat obsessive-compulsive disorder (OCD) and is recognized for its efficacy in reducing both obsessions and compulsions.
Inhaled Anesthetic
Nitrous Oxide for Obsessive-Compulsive Disorder
This trial uses nitrous oxide gas, commonly known as laughing gas, to see if it can quickly help people with OCD. It targets individuals with OCD because they often struggle with persistent and distressing thoughts and behaviors. The gas might work by altering brain chemicals to improve mood and reduce symptoms.
Trials With No Placebo
Deep Brain Stimulation
Deep Brain Stimulation for Obsessive-Compulsive Disorder
This trial is for people with a hard-to-control form of OCD. The goal is to find a more reliable system for treating OCD by studying how to best place electrodes in the brain to deliver electrical stimulation.
Selective Serotonin Reuptake Inhibitor
Fluoxetine for Obsessive-Compulsive Disorder
This trial uses brain scans and fluoxetine to treat unmedicated OCD patients. It aims to see how the brain changes with treatment and identify markers that predict treatment success. Fluoxetine, a selective serotonin reuptake inhibitor (SSRI), has been used for many years to treat obsessive-compulsive disorder (OCD) and is recognized for its efficacy in reducing both obsessions and compulsions.
Behavioral Intervention
Exposure Therapy for Child Anxiety
This trial will compare the effectiveness of three different types of treatment for anxiety disorders in children and adolescents. The three types of treatment are cognitive behavioral therapy with exposure (CBT), patient-centered telehealth CBT (PCT-CBT; patient-centered telehealth closed as of 5/1/21), and traditional outpatient CBT. The trial will involve 379 participants who will be randomly assigned to one of the three treatment groups. The primary outcome measures will be the changes in the participants' anxiety symptoms, functioning, and quality of life from baseline to follow-up.
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Frequently Asked Questions
Introduction to ocd
What are the top hospitals conducting ocd research?
Obsessive-Compulsive Disorder (OCD) affects millions of individuals worldwide, and in the quest for effective treatment options, certain hospitals have emerged as pioneers in clinical trials. Among them is Massachusetts General Hospital in Boston, where cutting-edge research on OCD is taking place with nine active trials and a total of 19 conducted studies to date. Since their first recorded trial in 2003, this esteemed institution has been at the forefront of understanding and treating this complex disorder. Meanwhile, Baylor College of Medicine in Houston has made remarkable strides since embarking on its inaugural OCD trial in 2017. With eight ongoing trials and a cumulative count of 17 experiments thus far, they are rapidly establishing themselves as a leading center for OCD research.
On the West Coast lies Stanford University—a renowned institution not only known for its prestigious academics but also for its contributions to advancing knowledge about OCD. Since conducting their first trial on this disorder in 2016, they have actively pursued eight current investigations alongside an impressive total of nine past studies. Additionally expanding geographical boundaries is Sunnybrook Health Sciences Centre located in Toronto; it may have five ongoing OCD trials but holds significant value having accomplished twelve experiments since initiating their pioneering investigation backin2006.
Lastly yet crucially situated within Philadelphia is the University of Pennsylvania—an institution dedicated to unraveling the mysteries surrounding OCD through both innovative therapies and clinical research endeavors. Having commenced their first documented trial concerning this condition backin2007,the university currently hosts four active OCD trials while having completed five previous investigations.
These top-tier hospitals represent beacons of hope for those affected by OCD—unyieldingly committed to improving treatments and quality-of-life outcomes for patients everywhere.Their collective efforts underscore that even though we may not yet fully understand this complex mental health condition or possess definitive cures,persistent exploration via rigorous clinical analysis ensures progress towards better understanding it's debilitating nature ultimately bringing us closer than ever before to alleviating suffering associated with OCD.
Which are the best cities for ocd clinical trials?
In the realm of OCD clinical trials, several cities emerge as prominent hubs for research and investigation. Boston, Massachusetts takes the lead with 14 active trials exploring treatments like Troriluzole, BX Pulsar 1002, and others. Miami, Florida also boasts 14 ongoing studies focusing on interventions such as Troriluzole (BHV-4157). Houston, Texas follows closely behind with 12 active trials investigating various approaches including Cognitive Behavioral Teletherapy LTA. Stanford, California showcases its dedication to OCD research through 11 ongoing trials examining interventions like Caloric Vestibular Stimulation. Lastly, New york, New York presents an array of opportunities with 10 current studies delving into potential treatments such as Celecoxib. These cities offer individuals affected by OCD access to cutting-edge clinical trials that hold promise for improved management and care.
Which are the top treatments for ocd being explored in clinical trials?
Ongoing clinical trials are exploring various treatments for obsessive-compulsive disorder (OCD), with some showing promising results. Troriluzole, a drug introduced in 2017, is currently being tested in three active OCD trials and has a total of three OCD trials to its name. Another potential treatment is celecoxib, first listed in 2021, which is undergoing evaluation in two ongoing OCD studies. Additionally, there are two active trials investigating the use of focused ultrasound as a therapeutic approach for OCD. Lastly, active stimulation therapy shows promise with one ongoing trial dedicated to studying its efficacy for treating individuals with OCD symptoms.
What are the most recent clinical trials for ocd?
Exciting progress in the field of OCD research has led to several recent clinical trials that hold promise for patients seeking effective treatment options. These trials include investigations into the use of psilocybin, a psychoactive compound found in certain mushrooms, which is being studied in Phase 1 trials as a potential therapy for OCD. Additionally, Tolcapone is undergoing Phase 2 testing as a pharmacological intervention for individuals with OCD symptoms. Another trial examines the combination of FMT capsules and SIMBA capsules, focusing on their effectiveness in managing OCD symptoms during Phase 2 studies. Furthermore, ongoing Phase 3 trials are evaluating an innovative treatment approach specifically designed to address the complexities of OCD. Lastly, cannabidiol (CBD) shows potential as an alternative therapy and is currently being evaluated through Phase 2 clinical trials for its efficacy in treating individuals with OCD symptoms.
What ocd clinical trials were recently completed?
The University of Arizona recently concluded a clinical trial focused on investigating the potential benefits of Psilocybin at a dosage of 300 mcg/kg for individuals with obsessive-compulsive disorder (OCD). This ground-breaking research, completed in January 2019, aimed to explore the therapeutic effects of Psilocybin in treating this challenging mental health condition. While further research is needed before any definitive conclusions can be drawn, these findings contribute to our understanding of alternative treatment options for OCD and offer hope for patients seeking new approaches to manage their symptoms.