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Dartmouth-Hitchcock Medical Center

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Lebanon, New Hampshire 03766

Global Leader in Lung Cancer

Global Leader in Cancer

Conducts research for Breast Cancer

Conducts research for Pancreatic Cancer

Conducts research for Non-Small Cell Lung Cancer

1082 reported clinical trials

83 medical researchers

Photo of Dartmouth-Hitchcock Medical Center in LebanonPhoto of Dartmouth-Hitchcock Medical Center in Lebanon

Summary

Dartmouth-Hitchcock Medical Center is a medical facility located in Lebanon, New Hampshire. This center is recognized for care of Lung Cancer, Cancer, Breast Cancer, Pancreatic Cancer, Non-Small Cell Lung Cancer and other specialties. Dartmouth-Hitchcock Medical Center is involved with conducting 1,082 clinical trials across 1,270 conditions. There are 83 research doctors associated with this hospital, such as Julie Kim, Kathryn C. Hourdequin, Konstantin H. Dragnev, and Manik A. Amin.

Area of expertise

1

Lung Cancer

Global Leader

Dartmouth-Hitchcock Medical Center has run 91 trials for Lung Cancer. Some of their research focus areas include:

Stage IV
Stage III
PD-L1 positive
2

Cancer

Global Leader

Dartmouth-Hitchcock Medical Center has run 84 trials for Cancer. Some of their research focus areas include:

Stage IV
Stage III
p16 positive

Top PIs

Clinical Trials running at Dartmouth-Hitchcock Medical Center

Lung Cancer

Cancer

Multiple Myeloma

Breast Cancer

Brain Tumor

Non-Small Cell Lung Cancer

Ovarian Cancer

Heart Attack

Pancreatic Cancer

Abdominal Aortic Aneurysm

Image of trial facility.

Dato-DXd + Pembrolizumab

for Advanced Lung Cancer

This study is designed to assess the efficacy and safety of datopotamab deruxtecan (Dato-DXd) in combination with pembrolizumab versus pembrolizumab alone in participants with advanced or metastatic non-small cell lung cancer (NSCLC) of non-squamous histology.

Recruiting

2 awards

Phase 3

13 criteria

Image of trial facility.

Daraxonrasib

for Non-Small Cell Lung Cancer

The purpose of this study is to evaluate the safety and efficacy of a novel RAS(ON) inhibitor compared to docetaxel.

Recruiting

2 awards

Phase 3

4 criteria

Image of trial facility.

Zongertinib

for Lung Cancer

This study is open to adults 18 years and older who have early-stage non-small cell lung cancer (NSCLC). Their cancer must have a specific change in a gene called HER2. Genes provide the instructions for making proteins, and this change leads to a faulty HER2 protein. People can join if their lung cancer was removed by surgery, and they have already received certain other anti-cancer treatments. The purpose of this study is to find out if a study medicine called zongertinib helps people with this type of cancer live longer without their cancer coming back after surgery, when compared to standard treatment. Zongertinib is being developed to target the faulty HER2 protein, which can cause cancer cells to grow. In this study, participants are assigned by chance to one of two treatment groups, with an equal chance of being in either group. One group takes the study medicine, zongertinib, by mouth once a day for up to 3 years. The other group receives a standard treatment, chosen by their doctor. This standard treatment may be an immunotherapy medicine given by infusion into a vein every 3 or 4 weeks for up to 1 year, or regular check-ups without active study medicine (observation). Participants can be in this study for up to about 11 years. During this time, they visit the study site regularly for check-ups and study-related tests. The frequency of these visits varies depending on their treatment and how long they have been in the study. In addition to visits at the study site, participants in some treatment groups will also have phone calls with the study team every 3 weeks to check on their health between their scheduled visits. Doctors check for any signs of cancer coming back using imaging scans (like CT or MRI scans); these scans are generally done every 3 months for the first 2 years, then every 6 months for the next 3 years, and then yearly. Participants also fill in questionnaires about their overall wellbeing, health and symptoms. Throughout the study, doctors also check participants' health and note any unwanted effects.

Recruiting

2 awards

Phase 3

6 criteria

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