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Duke University Medical Center

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Durham, North Carolina 27701
Global Leader in Cancer
Global Leader in Tumors
Conducts research for Leukemia
Conducts research for Breast Cancer
Conducts research for Lymphoma
2976 reported clinical trials
272 medical researchers
Photo of Duke University Medical Center in DurhamPhoto of Duke University Medical Center in Durham

Summary

Duke University Medical Center is a medical facility located in Durham, North Carolina. This center is recognized for care of Cancer, Tumors, Leukemia, Breast Cancer, Lymphoma and other specialties. Duke University Medical Center is involved with conducting 2,976 clinical trials across 2,418 conditions. There are 272 research doctors associated with this hospital, such as Lars Wagner, MD, Jessica M. Sun, Jeffrey Crawford, and Angeles A. Secord.

Area of expertise

1Cancer
Global Leader
Duke University Medical Center has run 248 trials for Cancer. Some of their research focus areas include:
Stage IV
Stage III
Stage I
2Tumors
Global Leader
Duke University Medical Center has run 159 trials for Tumors. Some of their research focus areas include:
Stage IV
Stage III
Stage I

Top PIs

Clinical Trials running at Duke University Medical Center

Non-Small Cell Lung Cancer
Lung Cancer
Breast Cancer
Cancer
Ovarian Tumors
Ovarian Carcinoma
Bladder Cancer
Dementia
Parkinson's Disease
Lymphoma
Image of trial facility.

Sotorasib Combo vs Pembrolizumab Combo

for Advanced Lung Cancer

This trial is testing two different drug combinations with chemotherapy to see which helps cancer patients live longer without their disease getting worse. One combination includes sotorasib, which targets cancer mutations, and the other includes pembrolizumab, which helps the immune system fight cancer. Pembrolizumab has been shown to improve overall survival in various cancers when combined with chemotherapy.
Recruiting2 awards Phase 33 criteria
Image of trial facility.

Ramucirumab + Pembrolizumab vs Chemotherapy

for Non-Small Cell Lung Cancer

This phase III trial compares the effect of the combination of ramucirumab and pembrolizumab versus standard of care chemotherapy for the treatment of non-small cell lung cancer that is stage IV or that has come back after a period of improvement (recurrent). Ramucirumab is a monoclonal antibody that may prevent the growth of new blood vessels that tumors need to grow. Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Chemotherapy drugs work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. This trial may help doctors find out if giving ramucirumab with pembrolizumab is more effective at treating patients with stage IV or recurrent non-small cell lung cancer than standard chemotherapy.
Recruiting2 awards Phase 310 criteria
Image of trial facility.

Crizotinib

for Non-Small Cell Lung Cancer

This randomized phase III trial studies how well crizotinib works in treating patients with stage IB-IIIA non-small cell lung cancer that has been removed by surgery and has a mutation in a protein called anaplastic lymphoma kinase (ALK). Mutations, or changes, in ALK can make it very active and important for tumor cell growth and progression. Crizotinib may stop the growth of tumor cells by blocking the ALK protein from working. Crizotinib may be an effective treatment for patients with non-small cell lung cancer and an ALK fusion mutation.
Recruiting2 awards Phase 328 criteria

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Frequently asked questions

What kind of research happens at Duke University Medical Center?
Duke University Medical Center is a medical facility located in Durham, North Carolina. This center is recognized for care of Cancer, Tumors, Leukemia, Breast Cancer, Lymphoma and other specialties. Duke University Medical Center is involved with conducting 2,976 clinical trials across 2,418 conditions. There are 272 research doctors associated with this hospital, such as Lars Wagner, MD, Jessica M. Sun, Jeffrey Crawford, and Angeles A. Secord.
Where is Duke University Medical Center located?
To reach Duke University Medical Center in Durham, North Carolina, take the 147 Durham Freeway Exit (Exit 279 B) from I-40. Then, follow the Elba Street/Trent Drive Exit (Exit 15 A).
Who should I call to ask about financial aid or insurance network?
**Duke University Medical Center Contact Information** - **Financial Assistance:** Accounting Systems Administration, (919) 684-2752, AcctgSysAdmin@duke.edu. Office hours: 8am-5pm, Mon-Fri. Location: 2200 West Main Street, Suite 300, Durham, NC 27705. - **Insurance Inquiries:** Corporate Risk Management, (919) 684-6226, corprisk@duke.edu. Office hours: 8am-5pm, Mon-Fri. Location: American Tobacco Campus, Washington Building, Suite 1000, 324 Blackwell Street, Durham, NC 27701. - **Clinical Risk Management:** (919) 684-3277, crm@duke.edu. Office hours: 8am-5pm, Mon-Fri. Location: 318 Baker House, Durham, NC 27710. - **Student Health Insurance Inquiries:** Duke Student Health Insurance team, insurance@studentaffairs.duke.edu. - **General Billing and Financial Resources:** Customer Service, 919-620-4555 (local), 1-800-782-6945 (toll-free). Hours: 8:00 am to 5:00 pm Monday, Tuesday, Wednesday, and Friday; 8:00 am to 4:00 pm Thursday.
What insurance does Duke University Medical Center accept?
The Duke University Medical Center accepts a range of commercial health insurance plans including Aetna, Blue Cross Blue Shield of North Carolina, Cigna Healthcare of NC, Humana, Optima Health, Progyny, and United Healthcare. It also participates in Medicare Advantage and Medicaid Managed Care plans in North Carolina, though not all services and benefits are covered, which may result in higher out-of-pocket expenses for patients. Duke University employees benefit from medical care plans covering pharmacy, behavioral health, and supplemental health insurance for international travel, with coverage extending to children under age 26 for medical, dental, and vision benefits.
What awards or recognition has Duke University Medical Center received?
Duke University School of Medicine ranks 7th nationally among academic medical centers, with over $551 million in NIH research funding in 2023. It boasts nine clinical and two basic science departments in the top 10 for NIH funding, demonstrating excellence in both clinical and basic science research.