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Hebrew Rehabilitation Center
Claim this profileRoslindale, Massachusetts 02131
Conducts research for Aging
Conducts research for Depression
Conducts research for Accidental Falls
Conducts research for Dementia
Conducts research for Alzheimer's Dementia
12 reported clinical trials
2 medical researchers
Summary
Hebrew Rehabilitation Center is a medical facility located in Roslindale, Massachusetts. This center is recognized for care of Aging, Depression, Accidental Falls, Dementia, Alzheimer's Dementia and other specialties. Hebrew Rehabilitation Center is involved with conducting 12 clinical trials across 8 conditions. There are 2 research doctors associated with this hospital, such as Brad Manor, PhD and Lewis Lipsitz, MD.Top PIs
Brad Manor, PhDHebrew Rehabilitation Center4 years of reported clinical research
Studies Aging
Studies Dementia
6 reported clinical trials
5 drugs studied
Lewis Lipsitz, MDHebrew Rehabilitation Center4 years of reported clinical research
Studies Aging
Studies Dementia
4 reported clinical trials
4 drugs studied
Clinical Trials running at Hebrew Rehabilitation Center
Aging
Accidental Falls
Depression
Alzheimer's Disease
Dementia
Alzheimer's Dementia
Home-based tDCS
for Older Adults at Risk of Falling
In this project, the investigators propose to demonstrate the feasibility of remotely-monitored, caregiver (or spouse)-administered, home-based tDCS intervention to improve mobility in ambulatory older adults with recent falls. This is a three-phase feasibility study in older, ambulatory adult participants at risk of falling due to a loss of balance (participant faller, PF) together with a willing and able participant administrator (PA) that is available during weekdays to administer tDCS (transcranial direct current stimulation) to the PF. Phase 1 is focused on the development and refinement of our training materials for home-based tDCS for PF/PA pairs. The objectives of this phase: 1. Identify areas of confusion and challenges for older adults. 2. Refine our training materials to accompany the home-based tDCS system. In Phase 2, the investigators will complete a pilot trial in 12 PF/PA pairs to assess the feasibility of deploying home-based tDCS in larger clinical trials, and to prepare for the development and implementation of such trials. The objectives of this phase: 1. Determine the mean/range number of visits needed for in-person training. 2. Compliance and retention with the study protocol. 3. Safety/side effects of home-based tDCS, as compared to previously established laboratory-based tDCS data. The investigators hypothesize that adult PAs are able to successfully administer home-based tDCS to PFs. The investigators also expect that PF/PA pairs will exhibit excellent adherence to the intervention and that the prevalence and severity of reported tDCS side-effects will be similar to that observed in previous laboratory-based studies. In Phase 3, the investigators will complete a pilot trial in up to 18 PF/PA pairs; i.e., those who have previously successfully completed either Phase 1 or Phase 2. The study objectives/aims for Phase 3 are: 1. Further explore compliance and retention with the study protocol over a longer time period 2. Identify safety/side effects of home-based tDCS over a longer time-period as compared to previously established laboratory-based tDCS interventions. In Phase 3, the investigators hypothesize that adult PA's who have previously demonstrated the ability to successfully administer tDCS at home, will retain competence and compliance with administration over a longer period, up to 1 year.
Recruiting1 award N/A10 criteria
Blueberry Powder
for Depression in Aging
This randomized, cross-over, pilot study aims to compare preliminary impact of a standard dose of blueberry powder (24 g) vs a higher dose (48 g) on the bioavailability of flavonoids and inflammatory biomarkers in older adults with minor levels of depressive symptoms.
Recruiting1 award N/A2 criteria
tDCS
for Preventing Falls in Elderly
The objective of this study is to determine if a four-week, 20-session intervention of personalized transcranial direct current stimulation (tDCS), as compared to sham intervention, improves dual task standing and walking performance (Aim 1), as well as other physical (Aim 2) and cognitive (Aim 3) factors on the causal pathway to falls, in older adults who report two or more falls within the past year and fear of falling again in the future, yet who do not have any acute or over neurological or musculoskeletal condition. Primary endpoints will include the "dual task" costs to gait speed when walking and postural sway speed when standing, as induced by performing a serial subtraction cognitive task (i.e., \[(speeddual task - speedsingle task) / speedsingle task) X 100\] (Aim 1), the Short Physical Performance Battery (Aim 2), and the Trail Making Test (Part B minus Part A) (AIM 3). Secondary endpoints will include the dual task cost to serial subtraction performance, additional gait and balance outcomes derived from the dual task paradigm, the Timed Up-and-Go, fear of falling, habitual physical activity, and performance within a battery of neuropsychological tests focused on global cognitive function, attention, verbal fluency and memory.
Recruiting0 awards N/A5 criteria
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Frequently asked questions
What kind of research happens at Hebrew Rehabilitation Center?
Hebrew Rehabilitation Center is a medical facility located in Roslindale, Massachusetts. This center is recognized for care of Aging, Depression, Accidental Falls, Dementia, Alzheimer's Dementia and other specialties. Hebrew Rehabilitation Center is involved with conducting 12 clinical trials across 8 conditions. There are 2 research doctors associated with this hospital, such as Brad Manor, PhD and Lewis Lipsitz, MD.