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Veterans Affairs Medical Center - Phoenix (Hayden)
Claim this profilePhoenix, Arizona 85012
Global Leader in Lung Cancer
Conducts research for Diabetes
Conducts research for Leukemia
Conducts research for Lymphoma
Conducts research for Type 2 Diabetes
130 reported clinical trials
5 medical researchers
Summary
Veterans Affairs Medical Center - Phoenix (Hayden) is a medical facility located in Phoenix, Arizona. This center is recognized for care of Lung Cancer, Diabetes, Leukemia, Lymphoma, Type 2 Diabetes and other specialties. Veterans Affairs Medical Center - Phoenix (Hayden) is involved with conducting 130 clinical trials across 150 conditions. There are 5 research doctors associated with this hospital, such as Aram Mardian, MD, Negin Blattman, MD, Peter Reaven, MD, and Daniel Soren Peterson, PhD MS BS.Top PIs
Aram Mardian, MDPhoenix VA Health Care System, Phoenix, AZ2 years of reported clinical research
Studies Chronic Lower Back Pain
Studies Back Pain
2 reported clinical trials
6 drugs studied
Negin Blattman, MDPhoenix VA Health Care System, Phoenix, AZ8 years of reported clinical research
Studies Clostridium
Studies C. Difficile
1 reported clinical trial
3 drugs studied
Peter Reaven, MDPhoenix VA Health Care System, Phoenix, AZ1 year of reported clinical research
Studies Atherosclerosis
Studies Prediabetes
1 reported clinical trial
2 drugs studied
Daniel Soren Peterson, PhD MS BSPhoenix VA Health Care System, Phoenix, AZ5 years of reported clinical research
Studies Multiple Sclerosis
1 reported clinical trial
1 drug studied
Clinical Trials running at Veterans Affairs Medical Center - Phoenix (Hayden)
Post-Traumatic Stress Disorder
Opioid Use Disorder
Diabetic Kidney Disease
Substance Use Disorders
Atherosclerosis
Prediabetes
Metformin
Osteomyelitis
Diabetes
Amputation
Mindfulness Training
for PTSD
The VA wants to understand what type of integrative and whole health approaches are helpful for Veterans. The study is comparing two primary care based mental health treatments, a mindfulness class that teaches mindfulness meditation and a problem-solving class that teaches problem-solving skills and how to build resilience, for Veterans who are experiencing symptoms of anxiety, depression, and/or PTSD. The goal of the study is to understand if the classes reduce symptoms of anxiety, depression, and/or PTSD and increase overall functioning.
Recruiting1 award N/A2 criteria
Cognitive Processing Therapy
for PTSD
Recent estimates suggest that over 610,000 US Veterans treated by the Veterans Health Administration (VHA) suffer from PTSD, a disorder that can be chronic and debilitating. The heterogeneity of the 20 symptoms of PTSD; comorbidity with disorders such as depression, panic, and substance use; high rates of lingering effects of physical injury; and suicidality all contribute to complex clinical presentations and can exact a significant toll on functioning, quality of life, and well-being even decades after exposure to the traumatic event. Perhaps spurred by the President's New Freedom Commission on Mental Health, psychosocial rehabilitation has shifted from the periphery in mental health recovery models to a more primary focus in clinical settings, including recommendations for use of psychosocial rehabilitation techniques in trauma-focused mental health care. Support for the efficacy of psychosocial rehabilitation techniques in PTSD recovery programs has burgeoned in recent years and data supporting psychological treatments for PTSD has increased exponentially, yet the two approaches to recovery have largely remained independent. Cognitive Processing Therapy (CPT), the evidence-based psychotherapy (EBP) for PTSD most frequently delivered within VHA, yields large magnitude reductions in primary PTSD outcomes. Corresponding gains in occupational, social, leisure, and sexual functioning, and in health-related concerns have also been demonstrated. Despite CPT's effectiveness, there is room for improvement in overall outcomes and patient engagement. Further, improvements in functioning and quality of life are more modest than those observed in PTSD and associated mental health symptoms. Prior work suggests that unaddressed difficulties in functioning contribute to premature dropout from EBPs for PTSD among Veterans. Directly targeting impairments associated with psychosocial functioning has the potential to substantially increase the scope of recovery beyond the core symptoms of PTSD and facilitate greater patient engagement, resulting in more Veterans benefitting from CPT. Modifying the CPT protocol to personalize the intervention for the individual patient has resulted in better overall response rates for a wider variety of patient populations suffering from complicated clinical presentations. Case formulation (CF) is a well-established approach to cognitive-behavioral treatment that facilitates a collaborative process between providers and patients to guide the tailoring of treatment to meet idiosyncratic patient needs. Integrating CF strategies into the existing CPT protocol will enable providers to personalize CPT to directly address impairment in functioning as well as provide the latitude to directly intervene with the complex challenges that threaten optimal outcomes within the context of trauma-focused therapy. CF-integrated CPT (CF-CPT) expands and enhances the CPT protocol to facilitate a personalized and flexible approach to treating PTSD that prioritizes the administration of the full dose of CPT while expanding the protocol to directly target important domains of functioning and result in more holistic outcomes. This controlled treatment outcome trial will randomize a national sample of CPT providers (Veteran n = 200; provider n = 50) to either deliver CF-CPT or CPT to compare the relative effectiveness of CF-CPT to CPT in improving primary outcomes, including Veterans' psychosocial functioning, quality of life and well-being over the course of treatment and 3-month follow-up as compared to Veterans who receive standard CPT. Further, Veterans who receive CF-CPT will demonstrate greater reductions in PTSD and depression over the course of treatment and 3-month follow-up than those who receive CPT. This study also seeks to determine the effectiveness of CF-CPT as compared to CPT in improving Veterans' treatment engagement (CF-CPT will demonstrate higher rates of Veteran treatment completion than CPT). This study will valuate CF-CPT's indirect impact on Veterans' psychosocial functioning and PTSD/depression symptomology Change in functioning, quality of life, and well-being \& PTSD and depression will be associated with improvement in the idiosyncratic clinical challenges targeted by the CF. This study will also examine between-group differences across secondary outcomes (e.g. anger, anxiety, health concerns, sleep, numbing/reactivity) and describe the frequency and type of the clinical and rehabilitative needs of the Veterans and the type and duration of divergences (e.g. rehabilitative techniques) made by providers.
Recruiting1 award N/A1 criteria
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Frequently asked questions
What kind of research happens at Veterans Affairs Medical Center - Phoenix (Hayden)?
Veterans Affairs Medical Center - Phoenix (Hayden) is a medical facility located in Phoenix, Arizona. This center is recognized for care of Lung Cancer, Diabetes, Leukemia, Lymphoma, Type 2 Diabetes and other specialties. Veterans Affairs Medical Center - Phoenix (Hayden) is involved with conducting 130 clinical trials across 150 conditions. There are 5 research doctors associated with this hospital, such as Aram Mardian, MD, Negin Blattman, MD, Peter Reaven, MD, and Daniel Soren Peterson, PhD MS BS.