Glioblastoma Clinical Trials in San Diego, CA

View the best 10 glioblastoma medical studies in San Diego, California. Access promising new therapies by applying to a San Diego-based Glioblastoma clinical trial.

Trials in San Diego, California

Here are the top 10 medical studies for glioblastoma in San Diego, California

Michael Bask Gill, B Sc

Last Reviewed: December 22nd, 2024

Selinexor +1 More

Selective Inhibitors of Nuclear Export

Recruiting1 awardPhase 1 & 2

This trial tests the safety and effectiveness of combining selinexor with radiation therapy in children and young adults with aggressive brain tumors. Selinexor is a drug that blocks a protein to stop cancer cells from growing. The study aims to find the best dose and see if this combination can shrink tumors.

Atezolizumab +1 More

Monoclonal Antibodies

Recruiting1 awardPhase 2

This trial tests a combination of tocilizumab, atezolizumab, and precise radiation therapy in patients with recurrent glioblastoma. Tocilizumab reduces inflammation, atezolizumab boosts the immune system, and the radiation targets the tumor. The goal is to make the tumor more responsive to treatment and improve patient outcomes.

Autologous genetically modified gamma-delta T cells +1 More

CAR T-cell Therapy

Recruiting1 awardPhase 1 & 2

This trial tests if a cell therapy can delay cancer return in GBM patients when combined with standard chemo. If it works, it should be studied further.

Bevacizumab +2 More

Monoclonal Antibodies

Recruiting1 awardPhase 2

This trial compares two treatments for patients with glioblastoma that has returned. One treatment uses pills that block enzymes needed for tumor growth. The other treatment uses an IV drug that helps the immune system fight cancer and prevents tumors from growing. The goal is to see which treatment works better at stopping the cancer from progressing.

BDTX-1535

Small Molecule Inhibitor

Recruiting1 awardPhase 1 & 2

This trial is testing a new drug for people with glioblastoma or non-small cell lung cancer who have disease progression following standard of care.

Bevacizumab +2 More

Monoclonal Antibodies

Recruiting1 awardPhase 2

This trial is testing the safety and effectiveness of a combination treatment for subjects with recurrent or progressive GBM using N-803, PD-L1 t-haNK, and Bevacizumab.

Temozolomide +2 More

Alkylating agents

Recruiting1 awardPhase 2

This trial is studying how well two types of radiation therapy work compared to standard radiation therapy when given with temozolomide in patients with newly diagnosed glioblastoma.

Temozolomide +2 More

Alkylating Agent

Recruiting1 awardPhase 2

This trial is studying a combination of drugs as a potential treatment for newly diagnosed malignant glioma. The drugs being studied are veliparib, radiation therapy, and temozolomide.

APL-101

Small Molecule Inhibitor

Recruiting1 awardPhase 2

This trial is testing APL-101, a new drug, on patients with specific genetic changes in their cancer. These patients often don't respond to typical treatments. The drug aims to block a protein that helps cancer cells grow and spread.

Lomustine +2 More

Alkylating agents

Recruiting2 awardsPhase 3

This trial is comparing the effect of adding lomustine to temozolomide and radiation therapy versus temozolomide and radiation therapy alone in treating newly diagnosed MGMT methylated glioblastoma.

Popular Filters

Trials With No Placebo

Monoclonal Antibodies

N-803 + PD-L1 t-haNK + Bevacizumab for Glioblastoma

Recruiting1 awardPhase 2

Newport Beach, California

This trial is testing the safety and effectiveness of a combination treatment for subjects with recurrent or progressive GBM using N-803, PD-L1 t-haNK, and Bevacizumab.

CAR T-cell Therapy

Gene-Modified T Cell Therapy for Glioblastoma

Recruiting1 awardPhase 1 & 2

La Jolla, California

This trial tests if a cell therapy can delay cancer return in GBM patients when combined with standard chemo. If it works, it should be studied further.

Selective Inhibitor of Nuclear Export

Selinexor + Temozolomide for Recurrent Glioblastoma

Recruiting1 awardPhase 1 & 2

La Jolla, California

This trial tests selinexor with temozolomide for patients whose brain cancer has returned. Selinexor blocks a protein that helps cancer cells grow, and temozolomide damages their DNA to kill them or stop their growth. Temozolomide is a DNA methylating drug currently used as a first-line treatment in glioblastoma therapy.

Focused Ultrasound

Focused Ultrasound BBBD for Glioblastoma

Recruiting1 award

Newport Beach, California

This trial aims to test the safety and effectiveness of using the Exablate device to temporarily open the blood-brain barrier in patients with suspected Glioblastoma. By doing this, doctors can collect fluid from the brain to check for cancer cells. The study will take place at up to 25 centers in the US.

Small Molecule Inhibitor

BDTX-1535 + Temozolomide for Glioblastoma and Lung Cancer

Recruiting1 awardPhase 1 & 2

Irvine, California

This trial is testing a new drug for people with glioblastoma or non-small cell lung cancer who have disease progression following standard of care.

Selective Inhibitors of Nuclear Export

Selinexor + Radiation for Brain Cancer

Recruiting1 awardPhase 1 & 2

San Diego, California

This trial tests the safety and effectiveness of combining selinexor with radiation therapy in children and young adults with aggressive brain tumors. Selinexor is a drug that blocks a protein to stop cancer cells from growing. The study aims to find the best dose and see if this combination can shrink tumors.

View More Related Trials

Temozolomide +2 More

Ramipril

VBI-1901

Olaparib

APL-101

Bevacizumab

Bevacizumab +2 More

Optune®

Nivolumab +1 More

Radiation Therapy

Fimepinostat

NanO2TM

Selinexor

Temozolomide +2 More

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Frequently Asked Questions

Do I need insurance to participate in a trial?

Almost all clinical trials will cover the cost of the 'trial drug' — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).

Is there any support for travel costs?

Many of the teams running clinical trials will cover the cost of transportation to-and-from their care center.

Will I know what medication I am taking?

This depends on the specific study. If you're worried about receiving a placebo, you can actively filter out these trials using our search.

How long do clinical trials last?

Some trials will only require a single visit, while others will continue until your disease returns. It's fairly common for a trial to last somewhere between 1 and 6 months.

Do you verify all the trials on your website?

All of the trials listed on Power have been formally registered with the US Food and Drug Administration. Beyond this, some trials on Power have been formally 'verified' if the team behind the trial has completed an additional level of verification with our team.

How quickly will I hear back from a clinical trial?

Sadly, this response time can take anywhere from 6 hours to 2 weeks. We're working hard to speed up how quickly you hear back — in general, verified trials respond to patients within a few days.