Dr. Christen Ebens, MD
Claim this profileMasonic Cancer Center, University of Minnesota
Studies Severe Combined Immunodeficiency
Studies Omenn Syndrome
5 reported clinical trials
9 drugs studied
Area of expertise
1Severe Combined Immunodeficiency
HLA positive
CD62L negative
CD45RO positive
2Omenn Syndrome
Affiliated Hospitals
Clinical Trials Christen Ebens, MD is currently running
Stem Cell Transplant Conditioning
for SCID
The investigators want to study if lower doses of chemotherapy will help babies with SCID to achieve good immunity with less short and long-term risks of complications after transplantation. This trial identifies babies with types of immune deficiencies that are most likely to succeed with this approach and offers them transplant early in life before they get severe infections or later if their infections are under control. It includes only patients receiving unrelated or mismatched related donor transplants. The study will test if patients receiving transplant using either a low dose busulfan or a medium dose busulfan will have immune recovery of both T and B cells, measured by the ability to respond to immunizations after transplant. The exact regimen depends on the subtype of SCID the patient has. Donors used for transplant must be unrelated or half-matched related (haploidentical) donors, and peripheral blood stem cells must be used. To minimize the chance of graft-versus-host disease (GVHD), the stem cells will have most, but not all, of the T cells removed, using a newer, experimental approach of a well-established technology. Once the stem cell transplant is completed, patients will be followed for 3 years. Approximately 9-18 months after the transplant, vaccinations will be administered, and a blood test measuring whether your child's body has responded to the vaccine will be collected.
Recruiting1 award Phase 244 criteria
JSP191
for Severe Combined Immunodeficiency (SCID)
This trial tests JSP191, an antibody, in SCID patients needing a blood stem cell transplant. JSP191 helps by clearing out old blood-forming cells to make room for new, healthy ones.
Recruiting1 award Phase 1 & 23 criteria
More about Christen Ebens, MD
Clinical Trial Related6 years of experience running clinical trials · Led 5 trials as a Principal Investigator · 3 Active Clinical TrialsTreatments Christen Ebens, MD has experience with
- Busulfan
- JSP191
- Allogeneic Hematopoetic Stem Cell Transplant
- Cyclosporine
- Fludarabine Phosphate
- Melphalan
Breakdown of trials Christen Ebens, MD has run
Severe Combined Immunodeficiency
Omenn Syndrome
Arterial Tortuosity Syndrome
Primary Immunodeficiency
Silvery Hair Syndrome
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Frequently asked questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the ‘trial drug’ — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
What does Christen Ebens, MD specialize in?
Christen Ebens, MD focuses on Severe Combined Immunodeficiency and Omenn Syndrome. In particular, much of their work with Severe Combined Immunodeficiency has involved HLA positive patients, or patients who are CD62L negative.
Is Christen Ebens, MD currently recruiting for clinical trials?
Yes, Christen Ebens, MD is currently recruiting for 3 clinical trials in Minneapolis Minnesota. If you're interested in participating, you should apply.
Are there any treatments that Christen Ebens, MD has studied deeply?
Yes, Christen Ebens, MD has studied treatments such as Busulfan, JSP191, Allogeneic Hematopoetic Stem Cell Transplant.
What is the best way to schedule an appointment with Christen Ebens, MD?
Apply for one of the trials that Christen Ebens, MD is conducting.
What is the office address of Christen Ebens, MD?
The office of Christen Ebens, MD is located at: Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota 55455 United States. This is the address for their practice at the Masonic Cancer Center, University of Minnesota.
Is there any support for travel costs?
The coverage of travel expenses can vary greatly between different clinical trials. Please see more financial detail in the trials you’re interested to apply.