Dr. Ioannis Mantzaris, MD
Claim this profileMontefiore Medical Center - Moses Campus
Studies Leukemia
Studies Acute Myeloid Leukemia
9 reported clinical trials
27 drugs studied
Area of expertise
1Leukemia
BCR-ABL1 positive
Philadelphia chromosome positive
t(9;22) translocation positive
2Acute Myeloid Leukemia
RARA positive
t(9;22) translocation positive
FLT3 positive
Affiliated Hospitals
Clinical Trials Ioannis Mantzaris, MD is currently running
Venetoclax + ASTX727
for Chronic Myelomonocytic Leukemia
This trial is testing if a combination of two drugs, ASTX727 and venetoclax, is more effective than ASTX727 alone in treating certain bone marrow cancers. It focuses on patients with CMML and MDS/MPN who have too many immature blood cells. ASTX727 helps produce normal blood cells and kills abnormal ones, while venetoclax blocks a protein that cancer cells need to survive. Venetoclax is an anticancer drug used to treat lymphomas and leukemias, but it has severe side effects.
Recruiting1 award Phase 2
Venetoclax + Chemotherapy
for Acute Myeloid Leukemia
This is a Phase 1b, open-label study evaluating Venetoclax in combination with intensive induction and consolidation chemotherapy in previously untreated, adult patients with acute myeloid leukemia. In Part 1, the dose escalation phase, the safety and tolerability of the combination with Venetoclax at different doses and duration will inform the appropriate dose(s) and regimen(s) for Part 2. In Part 2, the dose expansion phase, a maximum of 28 additional patients will be randomized 1:1 to the MTD determined in Part 1 and the starting dose (assuming the MTD is not the starting dose), to further evaluate the safety and efficacy of the study drug combination.
Recruiting1 award Phase 1
More about Ioannis Mantzaris, MD
Clinical Trial Related1 year of experience running clinical trials · Led 9 trials as a Principal Investigator · 6 Active Clinical TrialsTreatments Ioannis Mantzaris, MD has experience with
- Venetoclax
- Cytarabine
- Azacitidine
- Dexamethasone
- Decitabine And Cedazuridine
- Daunorubicin Hydrochloride
Breakdown of trials Ioannis Mantzaris, MD has run
Leukemia
Acute Myeloid Leukemia
Myeloid Leukemia
Myelodysplastic Syndrome
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Frequently asked questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the ‘trial drug’ — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
What does Ioannis Mantzaris, MD specialize in?
Ioannis Mantzaris, MD focuses on Leukemia and Acute Myeloid Leukemia. In particular, much of their work with Leukemia has involved BCR-ABL1 positive patients, or patients who are Philadelphia chromosome positive.
Is Ioannis Mantzaris, MD currently recruiting for clinical trials?
Yes, Ioannis Mantzaris, MD is currently recruiting for 6 clinical trials in Bronx New York. If you're interested in participating, you should apply.
Are there any treatments that Ioannis Mantzaris, MD has studied deeply?
Yes, Ioannis Mantzaris, MD has studied treatments such as Venetoclax, Cytarabine, Azacitidine.
What is the best way to schedule an appointment with Ioannis Mantzaris, MD?
Apply for one of the trials that Ioannis Mantzaris, MD is conducting.
What is the office address of Ioannis Mantzaris, MD?
The office of Ioannis Mantzaris, MD is located at: Montefiore Medical Center - Moses Campus, Bronx, New York 10467 United States. This is the address for their practice at the Montefiore Medical Center - Moses Campus.
Is there any support for travel costs?
The coverage of travel expenses can vary greatly between different clinical trials. Please see more financial detail in the trials you’re interested to apply.