Dr. Jocelyn Gravel, MD
Claim this profileCHU Sainte-Justine
Studies Recurrence
Studies Gastroenteritis
6 reported clinical trials
7 drugs studied
Affiliated Hospitals
Clinical Trials Jocelyn Gravel, MD is currently running
Sucrose Solution
for Pediatric Gastroenteritis
Background: Acute viral gastroenteritis is a very common pediatric medical condition that results in a large number of emergency department (ED) visits. Fasting-induced ketosis has been suggested to contribute to nausea and vomiting in children with VGE. To date, there is no data on the impact of oral sucrose intake during oral rehydration. Objective: The aim of this study is to assess the impact of providing a sucrose solution at triage to young children with suspected acute viral gastroenteritis on the amount of rehydration solution intake in the first 2 hours. We will also assess the proportion of discharge after initial medical evaluation, the proportion of oral rehydration failure, the number of vomiting episodes per patient, ondansetron administration, the time between the intervention and ED discharge, the time between the first medical contact and ED discharge and return visits within 48 hours. Methods: This study will be a double-blind randomized controlled trial. Recruitment will take place in a tertiary pediatric ED. Participants will be all children who present to the ED with suspected acute acute viral gastroenteritis with at least three vomiting in the previous 24 hours. The intervention will consist in giving 1.5 ml/kg of a sucrose solution composed of diluted juice with added table sugar (3.5g of sucrose/10 ml) compared with 1.5 ml/kg of diluted juice (0.5g of sucrose/10 mL, standard of care in our ED). Following that, all participants will be rehydrated with 15 mL of diluted juice every 15 minutes or more if tolerated. The primary outcome will be the amount of rehydration solution (ml) absorbed in the first two hours following intervention. Secondary outcomes will include disposition after initial medical evaluation, oral rehydration failure, the number of vomiting, ondansetron administration, the time between the intervention and ED discharge, the time between the first medical contact and ED discharge and return visits within 48 hours. The primary analysis will be the difference in the amount of tolerated oral rehydration between the two groups. Based on a preliminary study of children suffering from VGE, it was estimated that the recruitment of 238 participants would provide a power of 80% to identify a difference of 15 ml between the two groups. Expected results: We hope that this study will demonstrate that an oral sucrose solution given at triage to children presenting with symptoms compatible with acute acute viral gastroenteritis promotes oral hydration and consequently increases the total amount of rehydration solution tolerated by children.
Recruiting0 awards N/A
Amoxicillin
for Pneumonia
The aim of this study will be to evaluate whether a twice-daily antibiotic regimen is non-inferior to a thrice-daily regimen for the treatment of non-severe community acquired pneumonia in children presenting at a paediatric Emergency Department (ED).
Recruiting1 award Phase 2 & 35 criteria
More about Jocelyn Gravel, MD
Clinical Trial Related2 years of experience running clinical trials · Led 6 trials as a Principal Investigator · 4 Active Clinical TrialsTreatments Jocelyn Gravel, MD has experience with
- Sucrose
- Amoxicillin
- Valacyclovir
- Placebo
- Dexamethasone
- Placebo Group
Breakdown of trials Jocelyn Gravel, MD has run
Recurrence
Gastroenteritis
Pneumonia
Community-acquired Pneumonia
Other Doctors you might be interested in
Frequently asked questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the ‘trial drug’ — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
What does Jocelyn Gravel, MD specialize in?
Jocelyn Gravel, MD focuses on Recurrence and Gastroenteritis. In particular, much of their work with Recurrence has involved treating patients, or patients who are undergoing treatment.
Is Jocelyn Gravel, MD currently recruiting for clinical trials?
Yes, Jocelyn Gravel, MD is currently recruiting for 3 clinical trials in Montreal Quebec. If you're interested in participating, you should apply.
Are there any treatments that Jocelyn Gravel, MD has studied deeply?
Yes, Jocelyn Gravel, MD has studied treatments such as Sucrose, Amoxicillin, Valacyclovir.
What is the best way to schedule an appointment with Jocelyn Gravel, MD?
Apply for one of the trials that Jocelyn Gravel, MD is conducting.
What is the office address of Jocelyn Gravel, MD?
The office of Jocelyn Gravel, MD is located at: CHU Sainte-Justine, Montreal, Quebec H3T1C5 Canada. This is the address for their practice at the CHU Sainte-Justine.
Is there any support for travel costs?
The coverage of travel expenses can vary greatly between different clinical trials. Please see more financial detail in the trials you’re interested to apply.