Dr. Marielle Engelen, Ph.D.

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Texas A&M University

Studies Protein Metabolism
Studies Sarcopenia
4 reported clinical trials
11 drugs studied

Affiliated Hospitals

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Texas A&M University

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Human Clinical Research Facility

Clinical Trials Marielle Engelen, Ph.D. is currently running

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Amino Acid Supplements

for Protein Metabolism

Previous studies suggest that changes in metabolism due to the effects of aging might serve as a potential for therapeutic agents. The investigating lab developed a pulse method combining multiple stable isotopes to study multiple metabolic pathways in the same individual simultaneously. By measuring whole-body metabolism in a large group of older adults, the investigators may be able to unravel age-related deterioration in protein turnover (synthesis and breakdown) that contributes to impaired functional capacity. Metabolic profiles could explain differences in pathways in the aging process with special interest in metabolism of amino acids as they have been associated with aging-related disorders.

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Plant vs Whey Protein

for Protein Metabolism

The researchers overall objective is to determine whether plant and animal protein based proteins affect the anabolic responses across aging populations differently due to specific changes in the essential amino acids (EAA) and non-essential amino acids (NEAA) kinetic responses. The researchers central hypothesis is that a high EAA to NEAA ratio in a protein meal is related to higher anabolic response to the meal. The researchers also hypothesize that the type of NEAA in a protein meal also affects the anabolic capacity of the meal. The researchers rationale is that finding the amino acid composition of a meal that will maximally induce protein anabolism will guide novel nutritional approaches to prevent and treat sarcopenia, thereby reducing both overall economic burden and improving individual patient outcomes.

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More about Marielle Engelen, Ph.D.

Clinical Trial Related

3 years of experience running clinical trials · Led 4 trials as a Principal Investigator · 2 Active Clinical Trials

Treatments Marielle Engelen, Ph.D. has experience with

  • Peanut Protein
  • Organic Pea Protein Isolate
  • Soy Protein Isolate (90% Protein)
  • Whey Protein Isolate 90%
  • Hybrid Home-based And On-site Rehabilitation Program Utilizing Individually Tailored Exercises
  • Essential Amino Acids

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