Dr. Mehmet Sofuoglu, M.D., Ph.D.
Claim this profileVA Healthcare System
Studies Tobacco Use Disorder
Studies Nicotine Addiction
5 reported clinical trials
5 drugs studied
Affiliated Hospitals
Clinical Trials Mehmet Sofuoglu, M.D., Ph.D. is currently running
Dronabinol
for Pain Management in Opioid Users
Twenty male and female (ages 18-70) participants with OUD currently receiving methadone or buprenorphine will be enrolled. Prior to their daily methadone or buprenorphine dose and thus at trough plasma levels of opioid, participants will receive dronabinol (2.5 mg, 5mg) or placebo. Subsequently, all participants will undergo laboratory testing of opioid-related outcomes. Pain sensitivity will be measured using a technique called the (QST) quantitative sensory testing, which involves the administering heat or cold stimulation. A Short-Form McGill Pain Questionnaire (SF-MPQ) and a pain Visual Analog Scale (VAS). Attentional bias will be measured using a visual probe task. Negative affect will be measured using the Positive and Negative Affect Schedule (PANAS). Cognitive performance will be measured by a comprehensive cognitive battery. The order of study medication administration will be counterbalanced order to minimize carryover effects. On the initial screening day and at the end of medication treatment, blood will be drawn to determine serum cytokine levels. One week after the last study medication dose, a follow-up session will be conducted during which participants will undergo urine toxicology testing and a safety evaluation before final discharge from the study.
Recruiting0 awards Phase < 1
Nicotine Thresholds
for Smoking Addiction
To determine the nicotine threshold dose(s) for discrimination, subjective-rewarding effects, -and reinforcement in smokers with different levels of dependence.
Recruiting0 awards Phase < 18 criteria
More about Mehmet Sofuoglu, M.D., Ph.D.
Clinical Trial Related5 years of experience running clinical trials · Led 5 trials as a Principal Investigator · 2 Active Clinical TrialsTreatments Mehmet Sofuoglu, M.D., Ph.D. has experience with
- Nicotine
- Saline
- Dronabinol
- Placebo
- Cannabidiol
Breakdown of trials Mehmet Sofuoglu, M.D., Ph.D. has run
Tobacco Use Disorder
Nicotine Addiction
Smoking Addiction
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Frequently asked questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the ‘trial drug’ — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
What does Mehmet Sofuoglu, M.D., Ph.D. specialize in?
Mehmet Sofuoglu, M.D., Ph.D. focuses on Tobacco Use Disorder and Nicotine Addiction. In particular, much of their work with Tobacco Use Disorder has involved treating patients, or patients who are undergoing treatment.
Is Mehmet Sofuoglu, M.D., Ph.D. currently recruiting for clinical trials?
Yes, Mehmet Sofuoglu, M.D., Ph.D. is currently recruiting for 2 clinical trials in West Haven Connecticut. If you're interested in participating, you should apply.
Are there any treatments that Mehmet Sofuoglu, M.D., Ph.D. has studied deeply?
Yes, Mehmet Sofuoglu, M.D., Ph.D. has studied treatments such as Nicotine, Saline, Dronabinol.
What is the best way to schedule an appointment with Mehmet Sofuoglu, M.D., Ph.D.?
Apply for one of the trials that Mehmet Sofuoglu, M.D., Ph.D. is conducting.
What is the office address of Mehmet Sofuoglu, M.D., Ph.D.?
The office of Mehmet Sofuoglu, M.D., Ph.D. is located at: VA Healthcare System, West Haven, Connecticut 06516 United States. This is the address for their practice at the VA Healthcare System.
Is there any support for travel costs?
The coverage of travel expenses can vary greatly between different clinical trials. Please see more financial detail in the trials you’re interested to apply.