Dr. Samir I. Patel
Claim this profileCross Cancer Institute
Studies Brain Tumor
Studies Cancer
5 reported clinical trials
11 drugs studied
Affiliated Hospitals
Clinical Trials Samir I. Patel is currently running
Pre- vs Post-operative SRS
for Brain Cancer
The purpose of this study is to determine if performing radiotherapy (SRS) prior to surgery results in better treatment outcomes than performing surgery before radiotherapy for patients with brain metastases. Brain metastases occur when cancer cells from a primary cancer (e.g. lung, breast, colon) travel through the bloodstream and spread (metastasize) to the brain. As these new tumors grow they apply pressure and change how healthy brain tissue works. This can lead to a loss of brain function and worsening quality of life. Treatments for patients whose cancer has spread to the brain is often surgery, radiation therapy (radiotherapy) or a combination of both. Surgery is one the main treatments for brain tumors. To remove the tumor, a neurosurgeon makes an opening in the skull and attempts to the remove the entire tumor. If the tumor is too close to important brain tissue, the surgeon may attempt to remove part of the tumor. Removal of the tumor from the brain tissue is called resection. The complete or partial removal of tumor helps to relieve symptoms by reducing pressure on healthy tissues and reduces the amount of tumor that needs to be treated by radiotherapy. One type of radiotherapy used to treat brain metastases is stereotactic radiosurgery (SRS). SRS uses many focused radiation beams to treat tumors within the brain. Unlike surgery, there is no incision or cut being made. Instead, SRS uses an accurate map of your brain to deliver a precise beam of radiation to the tumors. The radiation damages the tumor cells forcing them to shrink and die off. The focused radiation beams also limit damage to healthy brain tissue minimizing side effects. Surgery followed by radiotherapy is a standard treatment for brain metastases. However, there are still risks associated with the combination of treatments. This study plans to investigate whether performing surgery prior to SRS results in improved quality of life and decreased side effects.
Recruiting2 awards Phase 37 criteria
Stereotactic Radiosurgery vs. HA-WBRT + Memantine
for Brain Cancer
Stereotactic radiosurgery (SRS) is a commonly used treatment for brain tumors. It is a one-day (or in some cases two day), out-patient procedure during which a high dose of radiation is delivered to small spots in the brain while excluding the surrounding normal brain. Whole brain radiation therapy with hippocampal avoidance (HA-WBRT) is when radiation therapy is given to the whole brain, while trying to decrease the amount of radiation that is delivered to the area of the hippocampus. The hippocampus is a brain structure that is important for memory. Memantine is a drug that is given to help relieve symptoms that can be caused by WBRT, including problems with memory and other mental symptoms. Health Canada, the regulatory body that oversees the use of drugs in Canada, has not approved the sale or use of memantine in combination with WBRT to treat this kind of cancer, although they have allowed its use in this study.
Recruiting2 awards Phase 3
More about Samir I. Patel
Clinical Trial Related2 years of experience running clinical trials · Led 5 trials as a Principal Investigator · 3 Active Clinical TrialsTreatments Samir I. Patel has experience with
- Standard Radiation Therapy
- Hypofractionated Radiation Therapy
- Stereotactic Radiosurgery
- Brain Surgery
- Single Fraction Stereotactic Radiosurgery
- Fractionated Stereotactic Radiosurgery
Breakdown of trials Samir I. Patel has run
Brain Tumor
Cancer
Brain Metastasis
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Frequently asked questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the ‘trial drug’ — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
What does Samir I. Patel specialize in?
Samir I. Patel focuses on Brain Tumor and Cancer. In particular, much of their work with Brain Tumor has involved Stage IV patients, or patients who are undergoing treatment.
Is Samir I. Patel currently recruiting for clinical trials?
Yes, Samir I. Patel is currently recruiting for 3 clinical trials in Edmonton Alberta. If you're interested in participating, you should apply.
Are there any treatments that Samir I. Patel has studied deeply?
Yes, Samir I. Patel has studied treatments such as Standard radiation therapy, Hypofractionated radiation therapy, Stereotactic Radiosurgery.
What is the best way to schedule an appointment with Samir I. Patel?
Apply for one of the trials that Samir I. Patel is conducting.
What is the office address of Samir I. Patel?
The office of Samir I. Patel is located at: Cross Cancer Institute, Edmonton, Alberta T6G 1Z2 Canada. This is the address for their practice at the Cross Cancer Institute.
Is there any support for travel costs?
The coverage of travel expenses can vary greatly between different clinical trials. Please see more financial detail in the trials you’re interested to apply.