Arthritis Clinical Trials in Columbus

View 10 new treatments for Arthritis in Columbus, OH. Every day, Power helps hundreds of Arthritis patients connect with leading medical research.

Baricitinib vs TNF Inhibitors for Rheumatoid Arthritis

Eli Lilly Clinic, Columbus + 1 more

This post-marketing study is designed to compare the safety of baricitinib versus tumor necrosis factor (TNF) inhibitors with respect to venous thromboembolic events (VTEs) when given to participants with rheumatoid arthritis.Show More
Waitlist

No Placebo Trial

Phase 4
Est. 3 - 12 Weeks
Call 1-877-CTLILLY (1-877-285-4559) or 1-317-615-4559 Mon - Fri 9 AM - 5 PM Eastern time (UTC/GMT - 5 hours, EST)
Study Director

Baricitinib for Rheumatoid Arthritis

Eli Lilly Clinic, Marion + 1 more

This trial compares the safety of two treatments for rheumatoid arthritis, focusing on the risk of blood clots. One treatment is baricitinib, an oral medication used for moderate to severe cases.Show More
Recruiting

No Placebo Trial

Phase 4
Est. 3 - 12 Weeks
Call 1-877-CTLILLY (1-877-285-4559) or 1-317-615-4559 Mon - Fri 9 AM - 5 PM Eastern time (UTC/GMT - 5 hours, EST)
Study Director

Amniotic Suspension Allograft for Knee Osteoarthritis

Organogenesis Clinic, Columbus + 1 more

This trial is testing if injecting ASA into the knee can help people with knee osteoarthritis feel better. The study will check pain levels, knee function, and safety over several months. ASA (Amniotic Suspension Allograft) has been shown to be an effective treatment for knee osteoarthritis in previous studies.Show More
Recruiting
Phase 3
Est. 3 - 6 Weeks
Unregistered Study Lead
Research Team

Abatacept Injection for Juvenile Idiopathic Arthritis

Research Clinic, Columbus + 1 more

This is a research study to test whether a once-weekly injection of abatacept will prevent the progression of Juvenile Idiopathic Arthritis (JIA) to a more severe form. To evaluate the effectiveness of a 24-week course of treatment with abatacept plus usual care versus usual care to prevent polyarthritis (≥5 joints), uveitis, or treatment with other systemic medication within 18 months of randomization in children with recent-onset limited JIA.Show More
Waitlist

No Placebo Trial

Phase 3
Est. 3 - 6 Weeks
Stephen Balevic, MD
Principal Investigator

ZILRETTA for Shoulder Osteoarthritis

Pacira Clinic, Columbus + 1 more

Primary Objective: To assess the efficacy of ZILRETTA on pain following an intra-articular (IA) injection in subjects with glenohumeral osteoarthritis (OA) relative to normal saline placebo Secondary Objective: * To assess the efficacy of ZILRETTA on pain following an IA injection in subjects with glenohumeral OA relative to triamcinolone acetonide injectable suspension, immediate release (TCA-IR) and normal saline placebo * To assess the safety of ZILRETTA in subjects with glenohumeral OA relative to normal saline placebo and TCA-IRShow More
Recruiting
Phase 3
Est. 4 - 6 Weeks
Nino Joy, MD
Study Director

Emapalumab for MAS in Still's Disease or Lupus

Swedish Orphan Biovitrum Clinic, Columbus + 1 more

This trial is testing emapalumab, a medication that helps control an overactive immune system, in children and adults with certain immune conditions who haven't responded to high-dose steroids. The goal is to see if it is safe and effective in reducing excessive inflammation. Emapalumab is a monoclonal antibody that targets interferon-γ and was first approved for treating primary hemophagocytic lymphohistiocytosis (HLH) in patients with refractory, recurrent, or progressive disease.Show More
Waitlist

No Placebo Trial

Phase 3
Est. 3 - 12 Weeks
Radmila Kanceva, MD
Study Chair

MFat vs Corticosteroid Injection for Knee Osteoarthritis

Lipogems Clinic, Columbus + 1 more

This trial is testing a new treatment where a patient's own fat is processed and injected into their knee to help with pain and function in people with moderate knee osteoarthritis. The goal is to see if this method works better by reducing inflammation and promoting healing. This approach has shown promising results in reducing pain and improving function.Show More
Waitlist

No Placebo Trial

Phase 3
Est. 4 - 6 Weeks
Unregistered Study Lead
Research Team

TTAX03 Injection for Knee Osteoarthritis

Tissue Tech Clinic, Columbus + 1 more

This trial tests if a single injection of TTAX03 in saltwater can improve knee conditions better than just saltwater. It targets patients needing knee injections and checks their response over a few months.Show More
Waitlist
Phase 2
Est. 3 - 12 Weeks
Unregistered Study Lead
Research Team

Metformin for Osteoarthritis After ACL Surgery

Research Clinic, Columbus + 1 more

This study is being done to find out if metformin is effective at reducing pain by delaying the onset of post-traumatic osteoarthritis (PTOA) after anterior cruciate ligament (ACL) reconstruction. This research study will compare metformin to placebo. The placebo tablet looks exactly like metformin, but contains no metformin. Placebos are used in research studies to see if the results are due to the study drug or due to other reasons. Metformin is approved by the U.S. Food and Drug Administration (FDA) to treat type II diabetes. Notably, it also has anti-inflammatory effects, suggesting it could benefit people who have an ACL injury and are undergoing ACL reconstruction.Show More
Recruiting
Phase 2
Est. 4 - 6 Weeks
Cale A Jacobs, PhD
Principal Investigator

CartiLife® for Osteoarthritis and Articular Cartilage Injury

Biosolution Clinic, Columbus + 1 more

This trial is testing a new treatment that uses small pellets made from a patient's own cartilage cells to repair knee damage. It targets adults with knee cartilage defects caused by injury or wear and tear. The treatment aims to reduce pain and improve knee function by helping the damaged cartilage heal and regrow.Show More
Recruiting

No Placebo Trial

Phase 2
Est. 5 - 8 Weeks
Jungsun Lee, Ph.D
Study Director
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