Depression Clinical Trials in Columbus
View 19 new treatments for depression near you in Columbus, OH near me. Every day, Power helps over 527 depression patients connect with leading medical research.SEP-363856 for Major Depressive Disorder
Otsuka Clinic, Columbus + 1 more
A Phase 2/3 Trial is designed to evaluate SEP-363856 as Adjunctive Therapy in the Treatment of Adults With Major Depressive Disorder
Verified
ALTO-300 for Depression
Alto Neuroscience Clinic, Columbus + 1 more
This trial is testing ALTO-300, a new medication, to see if it can make antidepressants work better for patients who are already taking them.
Verified
MBCT + IV Ketamine for Depression
Research Clinic, Columbus + 1 more
The purpose of this study is to assess the feasibility of combining IV ketamine, a rapid acting antidepressant, with a course of Mindfulness-Based Cognitive Therapy (MBCT), for the initial and maintenance treatment of depression.Show More
No Placebo Trial
Azithromycin for RSV-Induced Respiratory Failure
Research Clinic, Columbus + 1 more
The overarching hypothesis of the ARRC trial is that administration of Azithromycin (AZM) during acute, Respiratory Syncytial Virus (RSV)-induced respiratory failure will be beneficial, mediated through the matrix metalloproteinase (MMP)-9 pathway.Show More
Psilocybin for Major Depressive Disorder - TRD
COMPASS Pathways Clinic, Columbus + 1 more
This trial is testing COMP360, a new treatment for adults who have not responded to other depression treatments. Participants will receive one of three doses of COMP360 along with psychological support. The goal is to see if this combination can help improve their depression symptoms.Show More
No Placebo Trial
Tozorakimab for Viral Pneumonia
AstraZeneca Clinic, Columbus + 1 more
This trial is testing tozorakimab, a medication that may help people with severe viral lung infections who need extra oxygen. The goal is to see if it can prevent death or the need for advanced breathing support. Tozorakimab works by reducing harmful inflammation in the lungs.Show More
NMRA-335140 for Depression
Neumora Clinic, Columbus + 1 more
This trial is testing a new medication called NMRA-335140 to see if it helps people with major depressive disorder. It includes participants who have no safety concerns. The medication aims to improve mood by affecting brain chemicals.Show More
No Placebo Trial
Aticaprant for Depression
Janssen Clinic, Columbus + 1 more
This trial is testing aticaprant to see if it can help adults with major depressive disorder and anhedonia who haven't responded well to other antidepressants. Aticaprant works by blocking certain receptors in the brain to potentially improve depressive symptoms.Show More
NMRA 335140 for Depression
Neumora Clinic, Columbus + 1 more
This trial is testing a new medication called NMRA 335140 to see if it can help people with Major Depressive Disorder feel less depressed. The study involves an initial evaluation and a treatment phase where participants will receive either the medication or an inactive substance. The medication likely works by changing brain chemicals that affect mood.Show More
Ganciclovir for Acute Respiratory Failure
Research Clinic, Columbus + 1 more
This is a phase 3 study designed to evaluate whether the administration of ganciclovir increases ventilator-free days in immunocompetent patients with sepsis associated acute respiratory failure. Our hypothesis is that IV ganciclovir administered early in critical illness will effectively suppress CMV reactivation in CMV seropositive adults with sepsis-associated acute respiratory failure thereby leading to improved clinical outcomesShow More
Frequently Asked Questions
How much do depression clinical trials pay?
Each trial will compensate patients a different amount, but $50-100 for each visit is a fairly common range. Further, most trials will cover the costs of an Uber to-and-from the clinic. Factors that can affect compensation include the phase of the trial, the length of the trial, the frequency of visits, and the specific condition being studied.
Do I need to be insured to participate in a medical study?
Clinical trials are almost always free to participants, and so do not require insurance. The only exception here are trials focused on Cancer, because only a small part of the typical treatment plan is actually experimental. For these cancer trials, participants typically need insurance to cover all the non-experimental components.
How do depression clinical trials work?
After a researcher reviews your profile, they may choose to invite you in to a screening appointment, where they'll determine if you meet 100% of the eligibility requirements. If you do, you'll typical be sorted into one of the treatment groups, and will receive your study drug. For some trials, there is a chance you'll receive a placebo. Across depression trials in Columbus, 42% of clinical trials have a placebo. Typically you'll be required to check-in with the clinic every month or two. The average trial length in this city for depression patients is 6 Months.
What does the "phase" of a clinical trial mean?
The phase of a trial reveals what stage the drug is in getting approval for a specific condition. Phase 3 trials are in the final step before approval. The drug already has data showing both safety and effectiveness. Phase 2 trials are those where the drug has some data showing safety in humans, but where effectiveness has typically only been shown in animals and non-human experiments. Phase 1 trials are the trials where we don't have safety data in humans. As a general rule, phase 3 trials are more promising than phase 2, and phase 2 trials are more promising than phase 1.
Where in Columbus is research being conducted for depression?
Prominent hospitals in Columbus conducting clinical trials for depression include The Ohio State University and Nationwide Children's Hospital. Approximately 11 trials are ongoing as of 2023, primarily centered around the university area.
What promising new drugs are being tested?
In Columbus, research for depression includes treatments like Cognitive-behavioral skills building and Psychedelic Therapy. Specific interventions such as Psilocybin, Seltorexant, and Vagus Nerve Stimulation are also being explored.
Why are others applying to these studies?
I have tried two other drugs that didn't have any positive affect on my mental health and am hoping that trying out this trial will help me find a solution.
M.A. Patient
Depression Patient
I've tried many anti-depressants in my 45 year struggle with Major Depression. I'm hoping this study is the 'game changer'
B.E. Patient
Late-Life Depression Patient
I've tried more then 5 drugs for depression and it's very depressing frustrating when they do not work, or even help nothing, I'm still looking for that one or 2 that will help
A.L. Patient
Major Depression Patient