Depression Clinical Trials in Overland Park

View 13 new treatments for depression near you in Overland Park, KS near me. Every day, Power helps over 527 depression patients connect with leading medical research.
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ALTO-300 for Depression

Alto Neuroscience Clinic, Overland Park + 3 more

This trial is testing ALTO-300, a new medication, to see if it can make antidepressants work better for patients who are already taking them.

Verified

Recruiting
Phase 2
Est. 3 - 12 Weeks
Adam Savitz, MD, PhD
Study Director

AXS-05 for Depression

Axsome Clinic, Overland Park + 1 more

This trial is testing AXS-05, a new medication, to see if it can prevent depression from returning in people who have already improved with it. The study focuses on those with major depressive disorder and aims to maintain their balanced brain chemicals to keep them feeling better. AXS-05 (a combination of dextromethorphan and bupropion) has shown positive results in previous trials for major depressive disorder.Show More
Recruiting

No Placebo Trial

Phase 4
Est. 4 - 6 Weeks
Unregistered Study Lead
Research Team

REL-1017 for Depression

Relmada Clinic, Prairie Village + 3 more

This trial tests if adding REL-1017 to current antidepressant treatments can better help people with Major Depressive Disorder. Participants will take their usual antidepressants plus either REL-1017 or another substance. The goal is to see if REL-1017 can improve their depression symptoms. REL-1017 (esmethadone) has shown potential rapid and sustained antidepressant effects in previous trials.Show More
Recruiting
Phase 3
Est. 6 - 12 Weeks
Cedric O'Gorman, MD
Study Director

Aticaprant for Major Depressive Disorder

Janssen Clinic, Kansas City + 1 more

This trial is testing aticaprant to see if it can help people with major depressive disorder who still feel very down and don't enjoy things despite taking other antidepressants. The study focuses on adults who haven't responded well to their current treatments. Aticaprant works by blocking a specific brain receptor, which might help improve their mood and reduce depressive symptoms.Show More
Recruiting
Phase 3
Est. 5 - 8 Weeks
Janssen Research & Development, LLC Clinical Trial
Study Director

Lumateperone for Major Depressive Disorder

Intra-Cellular Therapies Clinic, Overland Park + 2 more

This trial is testing lumateperone, a medication that may help people with depression who haven't improved with other treatments. The study includes patients diagnosed with Major Depressive Disorder who haven't responded well to their current antidepressants. Lumateperone works by balancing brain chemicals that affect mood, potentially improving depressive symptoms.Show More
Recruiting
Phase 3
Est. 5 - 8 Weeks
Unregistered Study Lead
Research Team

Aticaprant for Depression

Janssen Clinic, Kansas City + 1 more

This trial is testing if adding aticaprant to current antidepressants is safe and well-tolerated in people with major depressive disorder. The goal is to see if it can help improve their treatment.Show More
Recruiting

No Placebo Trial

Phase 3
Est. 5 - 8 Weeks
Janssen Research & Development, LLC Clinical trial
Study Director

BHV-7000 for Depression

Biohaven Clinic, Overland Park + 1 more

This trial is testing a new medication called BHV-7000 to see if it helps people with severe depression and if it is safe.
Recruiting
Phase 2
Est. 3 - 12 Weeks
Unregistered Study Lead
Research Team

BHV-7000 for Depression

Biohaven Clinic, Overland Park + 1 more

This trial is testing a new medication called BHV-7000 to see if it is safe and well-tolerated over several months in people with Major Depressive Disorder. The goal is to help those who suffer from severe depression by potentially offering a new treatment option.Show More
Waitlist

No Placebo Trial

Phase 2
Est. 5 - 8 Weeks
Unregistered Study Lead
Research Team

Behavioral Activation for Alcohol Use Disorder

Research Clinic, Lawrence + 1 more

The transition from high school to college is a developmentally sensitive period that is high risk for escalations in alcohol use. Although risky drinking is a common problem among freshmen, engagement in treatment services is very low. The proposed study will test a behavioral activation intervention that addresses factors limiting participation in standard treatment services by targeting alcohol use indirectly, by directly addressing concerns most relevant to incoming college freshmen, and by integrating an intervention into the college curriculum.Show More
Recruiting

No Placebo Trial

Phase 2
Est. 3 - 12 Weeks
Tera L Fazzino, PhD
Principal Investigator

Ketamine for Suicidal Thoughts

Research Clinic, Kansas City + 2 more

There is currently no readily available pharmacologic intervention for suicidal ideation, a true psychiatric emergency, in the Emergency Department (ED). Investigators aim to trial low-dose, intravenous ketamine, a drug with well-established use in treatment-resistant depression, for patients who present to the ED with suicidal ideation.Show More
Recruiting

No Placebo Trial

Phase 1
Est. 3 - 6 Weeks
Unregistered Study Lead
Research Team
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Frequently Asked Questions

How much do depression clinical trials pay?

Each trial will compensate patients a different amount, but $50-100 for each visit is a fairly common range. Further, most trials will cover the costs of an Uber to-and-from the clinic. Factors that can affect compensation include the phase of the trial, the length of the trial, the frequency of visits, and the specific condition being studied.

Do I need to be insured to participate in a medical study?

Clinical trials are almost always free to participants, and so do not require insurance. The only exception here are trials focused on Cancer, because only a small part of the typical treatment plan is actually experimental. For these cancer trials, participants typically need insurance to cover all the non-experimental components.

How do depression clinical trials work?

After a researcher reviews your profile, they may choose to invite you in to a screening appointment, where they'll determine if you meet 100% of the eligibility requirements. If you do, you'll typical be sorted into one of the treatment groups, and will receive your study drug. For some trials, there is a chance you'll receive a placebo. Across depression trials in Overland Park, 42% of clinical trials have a placebo. Typically you'll be required to check-in with the clinic every month or two. The average trial length in this city for depression patients is 6 Months.

What does the "phase" of a clinical trial mean?

The phase of a trial reveals what stage the drug is in getting approval for a specific condition. Phase 3 trials are in the final step before approval. The drug already has data showing both safety and effectiveness. Phase 2 trials are those where the drug has some data showing safety in humans, but where effectiveness has typically only been shown in animals and non-human experiments. Phase 1 trials are the trials where we don't have safety data in humans. As a general rule, phase 3 trials are more promising than phase 2, and phase 2 trials are more promising than phase 1.

Why are others applying to these studies?

  • I have tried two other drugs that didn't have any positive affect on my mental health and am hoping that trying out this trial will help me find a solution.

    M.A. Patient

    Depression Patient

  • I've tried many anti-depressants in my 45 year struggle with Major Depression. I'm hoping this study is the 'game changer'

    B.E. Patient

    Late-Life Depression Patient

  • I've tried more then 5 drugs for depression and it's very depressing frustrating when they do not work, or even help nothing, I'm still looking for that one or 2 that will help

    A.L. Patient

    Major Depression Patient