Depression Clinical Trials in Salt Lake City

View 31 new treatments for depression near you in Salt Lake City, UT near me. Every day, Power helps over 527 depression patients connect with leading medical research.
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ALTO-300 for Depression

Alto Neuroscience Clinic, Clinton + 4 more

This trial is testing ALTO-300, a new medication, to see if it can make antidepressants work better for patients who are already taking them.

Verified

Recruiting
Phase 2
Est. 4 - 6 Weeks
Adam Savitz, MD, PhD
Study Director

Ketamine-assisted Psychotherapy for Gastrointestinal Cancer Distress

Research Clinic, Salt Lake City + 1 more

The goal of this open-label clinical trial is to assess the feasibility of Ketamine-assisted psychotherapy (KAP) studies for adults with non-operable GI cancers suffering with existential distress. The main questions it aims to answer are: * Is it feasible to conduct a KAP study with this population? * What is the safety and tolerability of KAP in this population? * How prevalent is existential distress in this population? Participants will undergo KAP administered as standard of care at the HMHI Park City Ketamine-Assisted Psychotherapy Clinic and will complete health assessments over the course of the study, as well as during the therapy.Show More
Recruiting

No Placebo Trial

Phase < 1
Est. 4 - 6 Weeks
Benjamin Lewis, MD
Principal Investigator

REL-1017 for Depression

Relmada Clinic, Draper + 1 more

This trial tests if adding REL-1017 to current antidepressant treatments can better help people with Major Depressive Disorder. Participants will take their usual antidepressants plus either REL-1017 or another substance. The goal is to see if REL-1017 can improve their depression symptoms. REL-1017 (esmethadone) has shown potential rapid and sustained antidepressant effects in previous trials.Show More
Recruiting
Phase 3
Est. 6 - 12 Weeks
Cedric O'Gorman, MD
Study Director

Seltorexant for Depression

Janssen Clinic, Draper + 1 more

This trial is testing seltorexant to see if it can help people with depression and insomnia who haven't improved with their current antidepressants. Seltorexant aims to improve mood and sleep by acting on certain brain receptors.Show More
Recruiting
Phase 3
Est. 3 - 12 Weeks
Janssen Research & Development, LLC Clinical Trail
Study Director

Psilocybin for Depression

Research Clinic, Draper + 2 more

This trial is testing psilocybin, a substance from mushrooms, to see if it can help adults with depression who may not respond well to current treatments. Psilocybin works by affecting brain chemicals related to mood. Psilocybin has shown promise as a treatment for major depressive disorder and was designated as a breakthrough therapy by the FDA in 2019.Show More
Recruiting
Phase 3
Est. 4 - 6 Weeks
Unregistered Study Lead
Research Team

Aticaprant for Major Depressive Disorder

Janssen Clinic, Clinton + 1 more

This trial is testing aticaprant to see if it can help people with major depressive disorder who still feel very down and don't enjoy things despite taking other antidepressants. The study focuses on adults who haven't responded well to their current treatments. Aticaprant works by blocking a specific brain receptor, which might help improve their mood and reduce depressive symptoms.Show More
Recruiting
Phase 3
Est. 5 - 8 Weeks
Janssen Research & Development, LLC Clinical Trial
Study Director

Psilocybin for Treatment-Resistant Depression

COMPASS Pathways Clinic, Murray + 3 more

This trial is testing a new medication called COMP360 to help people with severe depression that hasn't improved with other treatments. The study involves adults aged 18 and older. Researchers want to see if a single dose of COMP360 can reduce depression symptoms when given with psychological support.Show More
Recruiting
Phase 3
Est. 4 - 6 Weeks
Unregistered Study Lead
Research Team

Aticaprant + Antidepressant for Depression

Janssen Clinic, Clinton + 1 more

The purpose of this study is to assess how well aticaprant works compared to placebo when given in addition to antidepressant therapy (selective serotonin reuptake inhibitor \[SSRI\] or serotonin-norepinephrine reuptake inhibitor \[SNRI\]) in preventing return of depression symptoms in participants with major depressive disorder who experience a loss of interest and pleasure and who achieve a stable response after treatment with adjunctive aticaprant.Show More
Recruiting
Phase 3
Est. 5 - 8 Weeks
Janssen Research & Development, LLC Clinical Trial
Study Director

REL-1017 for Depression

Relmada Clinic, Clinton + 2 more

This trial tests REL-1017, a new drug, in people with major depression who aren't getting better with their current medication. The drug is taken regularly alongside their usual antidepressant to see if it helps improve their symptoms. REL-1017 has shown favorable safety, tolerability, and potential rapid and sustained antidepressant effects in previous trials.Show More
Recruiting
Phase 3
Est. 3 - 6 Weeks
Cedric O'Gorman, MD
Study Director

Psilocybin for Major Depressive Disorder - TRD

COMPASS Pathways Clinic, Salt Lake City + 1 more

This trial is testing COMP360, a new treatment for adults who have not responded to other depression treatments. Participants will receive one of three doses of COMP360 along with psychological support. The goal is to see if this combination can help improve their depression symptoms.Show More
Recruiting

No Placebo Trial

Phase 3
Est. 6 - 12 Weeks
Unregistered Study Lead
Research Team
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Frequently Asked Questions

How much do depression clinical trials pay?

Each trial will compensate patients a different amount, but $50-100 for each visit is a fairly common range. Further, most trials will cover the costs of an Uber to-and-from the clinic. Factors that can affect compensation include the phase of the trial, the length of the trial, the frequency of visits, and the specific condition being studied.

Do I need to be insured to participate in a medical study?

Clinical trials are almost always free to participants, and so do not require insurance. The only exception here are trials focused on Cancer, because only a small part of the typical treatment plan is actually experimental. For these cancer trials, participants typically need insurance to cover all the non-experimental components.

How do depression clinical trials work?

After a researcher reviews your profile, they may choose to invite you in to a screening appointment, where they'll determine if you meet 100% of the eligibility requirements. If you do, you'll typical be sorted into one of the treatment groups, and will receive your study drug. For some trials, there is a chance you'll receive a placebo. Across depression trials in Salt Lake City, 42% of clinical trials have a placebo. Typically you'll be required to check-in with the clinic every month or two. The average trial length in this city for depression patients is 6 Months.

What does the "phase" of a clinical trial mean?

The phase of a trial reveals what stage the drug is in getting approval for a specific condition. Phase 3 trials are in the final step before approval. The drug already has data showing both safety and effectiveness. Phase 2 trials are those where the drug has some data showing safety in humans, but where effectiveness has typically only been shown in animals and non-human experiments. Phase 1 trials are the trials where we don't have safety data in humans. As a general rule, phase 3 trials are more promising than phase 2, and phase 2 trials are more promising than phase 1.

Where in Salt Lake City is research being conducted for depression?

The University of Utah is a prominent hospital in Salt Lake City conducting clinical trials for depression, with approximately 5 trials ongoing as of 2023. These trials are primarily located in the eastern part of the city.

What promising new drugs are being tested?

In Salt Lake City, depression research includes treatments like Brain Stimulation and Psychedelic Therapy. Notable specific interventions being studied are Psilocybin, Propofol, and the VNS Therapy® System.

Why are others applying to these studies?

  • I have tried two other drugs that didn't have any positive affect on my mental health and am hoping that trying out this trial will help me find a solution.

    M.A. Patient

    Depression Patient

  • I've tried many anti-depressants in my 45 year struggle with Major Depression. I'm hoping this study is the 'game changer'

    B.E. Patient

    Late-Life Depression Patient

  • I've tried more then 5 drugs for depression and it's very depressing frustrating when they do not work, or even help nothing, I'm still looking for that one or 2 that will help

    A.L. Patient

    Major Depression Patient