Diabetes Clinical Trials in Atlanta

View 90 new treatments for Diabetes in Atlanta, GA, and other areas near me, such as Sandy Springs. Every day, Power helps hundreds of diabetes patients connect with leading medical research.
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Levodopa for Diabetic Retinopathy

Research Clinic, Decatur + 1 more

To determine if levodopa will slow the appearance of blood vessel changes in the eyes of patients with diabetes. Treatment will be started in patients with diabetes show delays in the electrical activity of the retina when measured non-invasively with a electroretinogram.Show More
Waitlist
Phase < 1
Est. 3 - 12 Weeks
Machelle T. Pardue, PhD
Principal Investigator

ILUVIEN® Implant for Diabetic Macular Edema

Alimera Sciences Clinic, Marietta + 2 more

This is a randomized, masked, active-controlled, parallel-group, multi-center study that will assess the efficacy of ILUVIEN as a baseline therapy in the treatment of Center Involving DME (CI-DME). The study will enroll patients who are either treatment naïve or have not received any DME treatments for the preceding 12 months as documented in medical records. Patients who received DME treatment \>12 months before screening, must not have received \>4 intravitreal injections. The study will compare 2 treatment regimens: ILUVIEN intravitreal implant (0.19 mg) followed by supplemental aflibercept as needed per protocol criteria (2 mg/0.05 mL), compared to intravitreal aflibercept loading dose (2 mg administered by intravitreal injection every 4 weeks for 5 consecutive doses) followed by supplemental aflibercept as needed per protocol criteria (2 mg/0.05 mL).Show More
Waitlist

No Placebo Trial

Phase 4
Est. 3 - 6 Weeks
Samer Kaba, MD
Study Chair

Metformin for Prediabetes

Research Clinic, Decatur + 1 more

This trial is testing whether metformin can lower the risk of death, heart attacks, and strokes in people with pre-diabetes and heart or blood vessel issues. Metformin is a drug that helps control blood sugar levels and has been used to treat type 2 diabetes mellitus for more than 60 years. The study involves patients who have pre-diabetes and existing heart or blood vessel problems, aiming to see if metformin can provide additional health benefits.Show More
Recruiting
Phase 4
Est. 5 - 8 Weeks
Gregory G. Schwartz, PhD MD
Study Chair

Tirzepatide for Type 2 Diabetes

Eli Lilly Clinic, Atlanta + 1 more

This study aims to investigate the efficacy and safety of tirzepatide in participants with type 2 diabetes (T2D) compared to other existing treatment options when treatment is initiated early.Show More
Waitlist

No Placebo Trial

Phase 4
Est. 4 - 6 Weeks
Call 1-877-CTLILLY (1-877-285-4559) or 1-317-615-4559 Mon - Fri 9 AM - 5 PM Eastern time (UTC/GMT - 5 hours, EST)
Study Director

Oral Anti-Diabetes Drugs vs Insulin for Diabetes

Research Clinic, Atlanta + 3 more

This randomized controlled clinical trial will assess whether continuation of home oral antidiabetic agents during hospitalization can be used as a safe and effective alternative to insulin therapy in the management of diabetes in the hospital. The primary outcome of the study is to determine differences in glycemic control as measured by mean daily blood glucose concentration between oral antidiabetic medications and basal bolus therapy in hospitalized patients with type 2 diabetes (T2D).Show More
Recruiting

No Placebo Trial

Phase 4
Est. 4 - 6 Weeks
Maya Fayfman, MD
Principal Investigator

Rifampin for Osteomyelitis in Diabetics

Research Clinic, Decatur + 1 more

The purpose of this research study is to determine if rifampin, an antibiotic (a medicine that treats infections), is effective in treating osteomyelitis (infection of the bone) of the foot in diabetic patients. Despite use of powerful antibiotics prescribed over a long period of time, many diabetic patients remain at a high risk for needing an amputation of part of the foot or lower leg because the osteomyelitis is not cured. Some small research studies have shown that addition of rifampin to other antibiotics is effective in treating osteomyelitis in both diabetics and non-diabetics. However, because few diabetics with osteomyelitis have been studied, there is no definite proof that it is better than the usual treatments for diabetic patients. If this study finds that adding rifampin to the usual antibiotics prescribed for osteomyelitis reduces the risk for amputations, doctors will be able to more effectively treat many Veteran patients with this serious infection. Improving treatment outcomes is an important healthcare goal of the VA.Show More
Recruiting
Phase 4
Est. 3 - 12 Weeks
Mary T Bessesen, MD
Study Chair

Continuous Glucose Monitoring and Insulin for Ketosis-Prone Diabetes

Research Clinic, Atlanta + 2 more

The goal of this study is to quantify day-to-day changes in blood glucose during treatment towards remission in ketosis-prone diabetes (KPDM) and describe them using a mathematical model of KPDM pathogenesis and remission.Show More
Recruiting

No Placebo Trial

Phase 4
Est. 3 - 6 Weeks
Priyathama Vellanki, MD, MS
Principal Investigator

Aflibercept for Diabetic Retinopathy

Research Clinic, Marietta + 1 more

The VOYAGE trial will assess diabetic retinopathy severity scale (DRSS) levels, through 112 weeks, while being managed with aflibercept as needed, among subjects who completed the 2-year PANORAMA trial (VGFTe-OD-1411) and were treated in a clinical setting prior to joining the VOYAGE study.Show More
Waitlist

No Placebo Trial

Phase 4
Est. 6 - 12 Weeks
Unregistered Study Lead
Research Team

Naltrexone + Bupropion for Obesity

Currax Clinic, Decatur + 2 more

This trial studies the effects of a medication combination (naltrexone and bupropion) on heart health. It targets patients to see if this treatment increases the risk of major heart problems. The study also includes advice on diet and exercise. Naltrexone and bupropion have been used in combination for weight loss, but they have been associated with various adverse effects, including neuropsychiatric disorders and cardiovascular risks.Show More
Recruiting
Phase 4
Est. 4 - 6 Weeks
Unregistered Study Lead
Research Team

Dulaglutide for Stress Hyperglycemia

Research Clinic, Atlanta + 2 more

Hyperglycemia is seen in approximately 30% of patients who do not have a history of diabetes and undergo general surgery. Hyperglycemia in this setting is associated with increased risk of postoperative complications. The purpose of this study is to investigate risk factors for developing high sugars during the time of surgery, and if these high sugars can be prevented by the use of an injectable diabetes medication (dulaglutide) prior to surgery.Show More
Recruiting
Phase 4
Est. 5 - 8 Weeks
Georgia Davis, MD
Principal Investigator
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Frequently Asked Questions

How much do diabetes clinical trials pay?

Each trial will compensate patients a different amount, but $50-100 for each visit is a fairly common range. Further, most trials will cover the costs of an Uber to-and-from the clinic. Factors that can affect compensation include the phase of the trial, the length of the trial, the frequency of visits, and the specific condition being studied.

Do I need to be insured to participate in a medical study?

Clinical trials are almost always free to participants, and so do not require insurance. The only exception here are trials focused on Cancer, because only a small part of the typical treatment plan is actually experimental. For these cancer trials, participants typically need insurance to cover all the non-experimental components.

How do diabetes clinical trials work?

After a researcher reviews your profile, they may choose to invite you in to a screening appointment, where they'll determine if you meet 100% of the eligibility requirements. If you do, you'll typical be sorted into one of the treatment groups, and will receive your study drug. For some trials, there is a chance you'll receive a placebo. Across diabetes trials in Atlanta, 42% of clinical trials have a placebo. Typically you'll be required to check-in with the clinic every month or two. The average trial length in this city for diabetes patients is 6 Months.

What does the "phase" of a clinical trial mean?

The phase of a trial reveals what stage the drug is in getting approval for a specific condition. Phase 3 trials are in the final step before approval. The drug already has data showing both safety and effectiveness. Phase 2 trials are those where the drug has some data showing safety in humans, but where effectiveness has typically only been shown in animals and non-human experiments. Phase 1 trials are the trials where we don't have safety data in humans. As a general rule, phase 3 trials are more promising than phase 2, and phase 2 trials are more promising than phase 1.

Where in Atlanta is research being conducted for diabetes?

Prominent hospitals in Atlanta conducting diabetes clinical trials include Grady Health System and Emory University Hospital. Trials are concentrated in the central and northeastern parts of the city, with approximately 27 ongoing as of 2024.

What promising new drugs are being tested?

In Atlanta, diabetes research is focusing on categories like Insulin therapies, Glucagon-like peptide-1 receptor agonists, and Mineralocorticoid Receptor Antagonists. Notable treatments being studied include Finerenone, Tirzepatide, and Afrezza.