Diabetes Clinical Trials in Springfield
View 13 new treatments for Diabetes in Springfield, IL near me. Every day, Power helps hundreds of Diabetes patients connect with leading medical research.ILUVIEN® Implant for Diabetic Macular Edema
Alimera Sciences Clinic, Springfield + 1 more
This is a randomized, masked, active-controlled, parallel-group, multi-center study that will assess the efficacy of ILUVIEN as a baseline therapy in the treatment of Center Involving DME (CI-DME). The study will enroll patients who are either treatment naïve or have not received any DME treatments for the preceding 12 months as documented in medical records. Patients who received DME treatment \>12 months before screening, must not have received \>4 intravitreal injections. The study will compare 2 treatment regimens: ILUVIEN intravitreal implant (0.19 mg) followed by supplemental aflibercept as needed per protocol criteria (2 mg/0.05 mL), compared to intravitreal aflibercept loading dose (2 mg administered by intravitreal injection every 4 weeks for 5 consecutive doses) followed by supplemental aflibercept as needed per protocol criteria (2 mg/0.05 mL).Show More
No Placebo Trial
RYBELSUS® for Type 2 Diabetes
Novo Nordisk Clinic, Gillespie + 3 more
This trial is testing RYBELSUS®, a tablet that lowers blood sugar, in people with type 2 diabetes who need extra treatment. The study will compare RYBELSUS® to other similar tablets over several months. Participants will have regular doctor visits and complete some questionnaires. Pregnant or breastfeeding women cannot join. RYBELSUS® is an oral form of a medication that has been used in injectable form for managing type 2 diabetes.Show More
No Placebo Trial
Tirzepatide vs Dulaglutide for Type 2 Diabetes
Eli Lilly Clinic, Springfield + 2 more
The purpose of the trial is to assess the efficacy and safety of tirzepatide to dulaglutide in participants with type 2 diabetes and increased cardiovascular risk.Show More
No Placebo Trial
IcoSema for Type 2 Diabetes
Novo Nordisk Clinic, Carlinville + 2 more
This trial will test a new weekly injection called IcoSema, which combines two drugs, in people with type 2 diabetes. The goal is to see if it controls blood sugar better than the existing drug, semaglutide. Participants will be randomly assigned to receive either IcoSema or semaglutide for several months.Show More
No Placebo Trial
Bevacizumab Safety for Retinal Disease
Outlook Clinic, Springfield + 1 more
The study will compare the safety of ophthalmic bevacizumab in vials versus pre-filled syringes in subjects diagnosed with a retinal condition that would benefit from treatment with intravitreal injection of bevacizumab, including: exudative age-related macular degeneration, diabetic macular edema, or branch retinal vein occlusion.Show More
No Placebo Trial
Tarcocimab for Diabetic Retinopathy
Kodiak Sciences Clinic, Springfield + 1 more
This study will demonstrate that tarcocimab 5 mg is superior to sham treatment in participants with moderately severe to severe NPDR.
Phage Therapy for Diabetic Foot Osteomyelitis
Adaptive Phage Clinic, Springfield + 1 more
This is a phase IIa randomized trial designed to evaluate bacteriophage therapy in patients with diabetic foot osteomyelitis.
Ladarixin for Type 1 Diabetes
Dompé Farmaceutici S.p.A Clinic, Springfield + 1 more
This trial is testing ladarixin, a medication that may help protect insulin-producing cells in the pancreas. It targets adolescents and adults who have been diagnosed with type 1 diabetes, especially those with severe cases. The goal is to see if ladarixin can slow down the progression of the disease and keep these cells working longer.Show More
Antimicrobial Peptide Spray for Diabetic Foot
Jiangsu ProteLight Clinic, Springfield + 1 more
This is a Phase II, randomized, double-blind, placebo-controlled, multi-center study to evaluate the clinical efficacy and safety of Antimicrobial Peptide PL-5 Topical Spray in patients with mild infections of diabetic foot ulcers. Eligible subjects will be randomized (1:1:1) to receive twice a day, 14 days treatment of Antimicrobial Peptide PL-5 Topical Spray (1‰), Antimicrobial Peptide PL-5 Topical Spray (2‰) and topical placebo (vehicle) spray. In this study, the cut-off date for final analysis is defined as the time when all subjects have completed the last visit or discontinued the studyShow More
Eversense CGM for Diabetes
Senseonics Clinic, Springfield + 1 more
This study is evaluating whether a continuous glucose monitor may help people with diabetes better manage their blood sugar.
No Placebo Trial
Frequently Asked Questions
How much do diabetes clinical trials pay?
Each trial will compensate patients a different amount, but $50-100 for each visit is a fairly common range. Further, most trials will cover the costs of an Uber to-and-from the clinic. Factors that can affect compensation include the phase of the trial, the length of the trial, the frequency of visits, and the specific condition being studied.
Do I need to be insured to participate in a medical study?
Clinical trials are almost always free to participants, and so do not require insurance. The only exception here are trials focused on Cancer, because only a small part of the typical treatment plan is actually experimental. For these cancer trials, participants typically need insurance to cover all the non-experimental components.
How do diabetes clinical trials work?
After a researcher reviews your profile, they may choose to invite you in to a screening appointment, where they'll determine if you meet 100% of the eligibility requirements. If you do, you'll typical be sorted into one of the treatment groups, and will receive your study drug. For some trials, there is a chance you'll receive a placebo. Across diabetes trials in Springfield, 42% of clinical trials have a placebo. Typically you'll be required to check-in with the clinic every month or two. The average trial length in this city for diabetes patients is 6 Months.
What does the "phase" of a clinical trial mean?
The phase of a trial reveals what stage the drug is in getting approval for a specific condition. Phase 3 trials are in the final step before approval. The drug already has data showing both safety and effectiveness. Phase 2 trials are those where the drug has some data showing safety in humans, but where effectiveness has typically only been shown in animals and non-human experiments. Phase 1 trials are the trials where we don't have safety data in humans. As a general rule, phase 3 trials are more promising than phase 2, and phase 2 trials are more promising than phase 1.
Where in Springfield is research being conducted for diabetes?
In Springfield, diabetes clinical trials are being conducted at Clinvest Research LLC, with approximately 4 trials ongoing. These trials are primarily located in the southern part of the city as of 2024.
What promising new drugs are being tested?
In Springfield, diabetes research is focusing on treatments like Glucagon-like peptide-1 receptor agonists and Monoclonal Antibodies. Notable specific interventions being studied include Tirzepatide, Dulaglutide, and the Eversense CGM System.