Eczema (Atopic Dermatitis) Clinical Trials in Cincinnati

View 15 new treatments for Eczema (Atopic Dermatitis) in Cincinnati, OH near me. Every day, Power helps hundreds of Eczema (Atopic Dermatitis) patients connect with leading medical research.
View 16 trials in Cincinnati
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Amlitelimab for Atopic Dermatitis (COAST 2)

Sanofi Clinic, Cincinnati + 3 more

This trial tests amlitelimab injections for patients aged 12 and older with moderate to severe atopic dermatitis that isn't controlled by topical treatments. The injections aim to reduce inflammation and symptoms by targeting specific immune pathways.Show More

Verified

Recruiting
Phase 3
Est. 3 - 6 Weeks
Unregistered Study Lead
Research Team

Transcriptomic Skin Analysis for Atopic Dermatitis

Research Clinic, Cincinnati + 1 more

This is a multi-center, longitudinal study which will characterize the gene expression profiles and transcriptomic endotypes that underlie mild and moderate-severe Atopic dermatitis (AD) and will determine changes in these expression patterns and endotypes in response to standard-of-care treatment. Participants will complete up to ten scheduled study visits with assessment of topical steroid response and dupilumab response (if uncontrolled with topical steroids). Skin samples will be collected at all study visits to determine the gene expression profiles and transcriptomic endotypes that underlie mild vs. moderate-severe AD disease. The investigators will also evaluate the lipidomic, metabolomic, proteomic, and microbiome profiles of AD skin endotypes associated with mild and moderate-severe AD disease. Non-AD participants will serve as a control population. The primary objective of this study is to determine if the type 2-high non-lesional skin (skin tape) endotype is associated with current mild versus moderate-severe AD disease.Show More
Recruiting

No Placebo Trial

Phase 4
Est. 5 - 8 Weeks
Max A. Seibold, Ph.D.
Study Chair

Nemolizumab for Eczema

Galderma Clinic, Cincinnati + 1 more

Long-Term Safety and Efficacy of Nemolizumab in Subjects with Moderate-to-Severe Atopic Dermatitis Description
Waitlist

No Placebo Trial

Phase 3
Est. 5 - 8 Weeks
Unregistered Study Lead
Research Team

Amlitelimab + Topical Corticosteroids for Atopic Dermatitis (AQUA)

Sanofi Clinic, Cincinnati + 1 more

This is a parallel group, Phase 3, multinational, multicenter, randomized, double-blind, placebo-controlled, 3-arm study for treatment of participants diagnosed with moderate-to-severe AD on background TCS who have had inadequate response to prior biologic or oral JAKi therapy. The purpose of this study is to measure the efficacy and safety of treatment with amlitelimab solution for subcutaneous (SC) injection compared with placebo in participants with moderate-to-severe AD aged 12 years and older on background TCS and have had an inadequate response to prior biologic or an oral JAKi therapy. Study details include: At the end of the treatment period, participants will have the option to enter the Long-Term Safety Study LTS17367 (RIVER-AD). The study duration will be up to 56 weeks for participants not entering the long-term safety study (LTS17367 \[RIVER-AD\]) including a 2 to 4-week screening, a 36-week randomized double-blind period, and a 16-week safety follow-up. The study duration will be up to 40 weeks for participants entering the long-term safety study (LTS17367 \[RIVER-AD\]) including a 2 to 4-week screening and a 36-week randomized double-blind period. The total treatment duration will be up to 36 weeks. The total number of visits will be up to 13 visits (or 12 visits for those entering the long-term safety study LTS17367 \[RIVER-AD\] study).Show More
Recruiting
Phase 3
Est. 4 - 6 Weeks
Unregistered Study Lead
Research Team

Rocatinlimab for Atopic Dermatitis/Eczema

Amgen Clinic, Cincinnati + 1 more

This trial is testing rocatinlimab to see if it is safe and can be tolerated by people with moderate-to-severe eczema. The medication works by calming the immune system to reduce skin inflammation and irritation.Show More
Recruiting
Phase 3
Est. 3 - 12 Weeks
MD
Study Director

Povorcitinib for Prurigo Nodularis

Incyte Clinic, Dayton + 1 more

The purpose of this study is to evaluate effect of povorcitinib on itch and skin lesions in participants with prurigo nodularis.
Recruiting
Phase 3
Est. 3 - 12 Weeks
Incyte Medical Monitor
Study Director

Povorcitinib for Prurigo Nodularis

Incyte Clinic, Cincinnati + 1 more

The purpose of this study is to evaluate effect of povorcitinib on itch and skin lesions in participants with prurigo nodularis.
Recruiting
Phase 3
Est. 3 - 12 Weeks
Incyte Medical Monitor
Study Director

Nemolizumab for Prurigo Nodularis

Galderma Clinic, Cincinnati + 1 more

This trial is testing the safety of nemolizumab, a medication for people with prurigo nodularis. Prurigo nodularis is a skin condition that causes itchy, hard lumps. Nemolizumab aims to reduce itching and swelling by blocking certain signals in the body.Show More
Waitlist

No Placebo Trial

Phase 3
Est. 6 - 12 Weeks
Unregistered Study Lead
Research Team

Barzolvolimab for Prurigo Nodularis

Celldex Clinic, Cincinnati + 1 more

The purpose of this study is to assess the efficacy and safety of barzolvolimab in adults with prurigo nodularis.
Recruiting
Phase 2
Est. 6 - 12 Weeks
Unregistered Study Lead
Research Team

Skin Barrier Cream + Fluticasone Propionate for Eczema

Research Clinic, Cincinnati + 1 more

This trial is testing whether using a special moisturizing cream and a mild steroid cream can help infants with early signs of eczema. The goal is to see if this treatment can reduce eczema severity and prevent food allergies. The study focuses on very young babies who have dry skin or early eczema symptoms. EpiCeramâ„¢ has been previously tested for preventing eczema in infants with a family history of allergic disease.Show More
Recruiting

No Placebo Trial

Phase 2
Est. 5 - 8 Weeks
Kari Nadeau, MD, PhD
Principal Investigator
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Frequently Asked Questions

How much do eczema clinical trials pay?

Each trial will compensate patients a different amount, but $50-100 for each visit is a fairly common range. Further, most trials will cover the costs of an Uber to-and-from the clinic. Factors that can affect compensation include the phase of the trial, the length of the trial, the frequency of visits, and the specific condition being studied.

Do I need to be insured to participate in a medical study?

Clinical trials are almost always free to participants, and so do not require insurance. The only exception here are trials focused on Cancer, because only a small part of the typical treatment plan is actually experimental. For these cancer trials, participants typically need insurance to cover all the non-experimental components.

How do eczema clinical trials work?

After a researcher reviews your profile, they may choose to invite you in to a screening appointment, where they'll determine if you meet 100% of the eligibility requirements. If you do, you'll typical be sorted into one of the treatment groups, and will receive your study drug. For some trials, there is a chance you'll receive a placebo. Across eczema trials in Cincinnati, 42% of clinical trials have a placebo. Typically you'll be required to check-in with the clinic every month or two. The average trial length in this city for eczema patients is 6 Months.

What does the "phase" of a clinical trial mean?

The phase of a trial reveals what stage the drug is in getting approval for a specific condition. Phase 3 trials are in the final step before approval. The drug already has data showing both safety and effectiveness. Phase 2 trials are those where the drug has some data showing safety in humans, but where effectiveness has typically only been shown in animals and non-human experiments. Phase 1 trials are the trials where we don't have safety data in humans. As a general rule, phase 3 trials are more promising than phase 2, and phase 2 trials are more promising than phase 1.

Where in Cincinnati is research being conducted for eczema?

Prominent hospitals or neighborhoods in Cincinnati conducting clinical trials for eczema are not explicitly listed. However, trials are actively conducted in various locations, with a focus on dermatology research.

What promising new drugs are being tested?

In Cincinnati, eczema research is focusing on treatments like Monoclonal Antibodies and Janus Kinase (JAK) Inhibitors. Notable drugs being studied include Dupilumab, Tralokinumab, and Upadacitinib.