Osteoarthritis Clinical Trials in Chicago
View 39 new treatments for Osteoarthritis in Chicago, IL, and nearby areas, such as Naperville. Every day, Power helps hundreds of osteoarthritis patients connect with leading medical research.Filter Results
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NSAIDs for Knee Osteoarthritis
Research Clinic, Chicago + 1 more
This trial is testing naproxen, a common pain reliever, in people with painful knee osteoarthritis. Naproxen helps reduce swelling and pain by blocking certain chemicals in the body. Participants will receive naproxen to compare its effects. Naproxen has been shown to be an effective and well-tolerated drug for the treatment of osteoarthritis of the hip and knee in previous studies.Show More
Recruiting
Phase 4
Est. 3 - 6 Weeks
Thomas J Schnitzer, MD, PhD
Principal Investigator
Pain Medication for Knee Osteoarthritis
Research Clinic, Chicago + 1 more
This is a clinical trial of people who have pain due to knee osteoarthritis at Northwestern University Feinberg School of Medicine. The study will last for about 20 weeks. 180 qualified participants will be randomly assigned in a 1:1:1 ratio (60 participants per group) to one of three treatment groups: duloxetine, celecoxib, or placebo. Participants will have an Xray, knee MRI, brain MRI, blood draws, pain sensitivity testing, and asked to fill out questionnaires. The purpose of this study is to try to predict which participants will respond to the treatment.Show More
Recruiting
Phase 4
Est. 3 - 12 Weeks
Thomas J Schnitzer, MD, PhD
Principal Investigator
TG-C for Knee Osteoarthritis
Kolon TissueGene Clinic, Chicago + 4 more
This trial tests TG-C, an injection into the knee, for people with moderate to severe knee osteoarthritis. It aims to see if TG-C can reduce pain and improve knee function by potentially altering the disease. The study will monitor patients for safety and effectiveness over time. TG-C has been previously studied for its potential to improve knee joint function and reduce pain in osteoarthritis patients.Show More
Waitlist
Phase 3
Est. 5 - 8 Weeks
David W Romness, MD
Principal Investigator
Non-Surgical Interventions for Knee Osteoarthritis
Research Clinic, Chicago + 1 more
There is an urgent public health need to reduce reliance on opioids for effective long-term pain management, particularly in knee osteoarthritis (KOA). This effectiveness trial will compare commonly recommended treatments to reduce pain and functional limitations in KOA.These results will lead to improved patient selection for treatment and inform evidence based guidelines by offering well-tested, effective, non-surgical alternatives.Show More
Recruiting
No Placebo Trial
Phase 3
Est. 6 - 12 Weeks
Steven Cohen, MD
Principal Investigator
Amniotic Suspension Allograft for Knee Osteoarthritis
Organogenesis Clinic, Chicago + 3 more
This trial is testing if injecting ASA into the knee can help people with knee osteoarthritis feel better. The study will check pain levels, knee function, and safety over several months. ASA (Amniotic Suspension Allograft) has been shown to be an effective treatment for knee osteoarthritis in previous studies.Show More
Recruiting
Phase 3
Est. 5 - 8 Weeks
Unregistered Study Lead
Research Team
RTX-GRT7039 Injections for Knee Osteoarthritis
Grünenthal Clinic, Chicago + 1 more
This trial uses knee injections called RTX-GRT7039 for patients with knee osteoarthritis who still have pain despite usual treatments. The injections aim to reduce knee pain, possibly by affecting pain pathways or inflammation.Show More
Waitlist
No Placebo Trial
Phase 3
Est. 3 - 6 Weeks
Unregistered Study Lead
Research Team
RTX-GRT7039 Injection for Osteoarthritis
Grünenthal Clinic, Hazel Crest + 2 more
This trial tests a special injection called RTX-GRT7039 to help reduce knee pain in people with osteoarthritis who still have pain despite usual treatments. The injection works by blocking pain signals from the knee.Show More
Waitlist
Phase 3
Est. 5 - 8 Weeks
Unregistered Study Lead
Research Team
Retatrutide for Obesity
Eli Lilly Clinic, Chicago + 1 more
This trial is testing a weekly medication called retatrutide. It aims to help people who are overweight or obese and have knee osteoarthritis. The study will last over a year to see if the medication is safe and effective.Show More
Waitlist
Phase 3
Est. 4 - 6 Weeks
Call 1-877-CTLILLY (1-877-285-4559) or 1-317-615-4559 Mon - Fri 9 AM - 5 PM Eastern time (UTC/GMT - 5 hours, EST)
Study Director
Retatrutide for Obesity
Eli Lilly Clinic, Chicago + 1 more
The purpose of this study is to evaluate the efficacy and safety of retatrutide in participants who have obesity or overweight (J1I-MC-GZBJ master protocol) including subsets of participants who have knee osteoarthritis (OA) (J1I-MC-GOA1) or who have obstructive sleep apnea (OSA) (J1I-MC-GSA1). This study will last about 89 weeks and will include up to 24 visits.Show More
Waitlist
Phase 3
Est. 3 - 6 Weeks
Call 1-877-CTLILLY (1-877-285-4559 or 1-317-615-4559 Mon - Fri 9 AM - 5 PM Eastern Time (UTC/GMT - 5 hours, EST)
Study Director
Dronabinol for Knee Surgery Pain
Research Clinic, Chicago + 1 more
The purpose of the proposed study is to evaluate the efficacy of dronabinol for postoperative pain after arthroscopic surgery of the knee. The investigators hypothesize that dronabinol will relieve pain, reduce opioid consumption and will result in few negative side effects. If this pilot study shows promising results the investigators will expand the trial to include additional arthroscopic surgeries (hip, shoulder) and other types of orthopaedic surgery.Show More
Recruiting
Phase 3
Est. 5 - 8 Weeks
Vehniah K Tjong, MD
Principal Investigator
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