Osteoarthritis Clinical Trials in Sacramento

View 11 new treatments for Osteoarthritis in Sacramento, CA, and other areas near me, such as Elk Grove, Fairfield, Roseville and Vacaville. Every day, Power helps hundreds of osteoarthritis patients connect with leading medical research.
View 9 trials in Sacramento
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Non-Surgical Interventions for Knee Osteoarthritis

Research Clinic, Sacramento + 1 more

There is an urgent public health need to reduce reliance on opioids for effective long-term pain management, particularly in knee osteoarthritis (KOA). This effectiveness trial will compare commonly recommended treatments to reduce pain and functional limitations in KOA.These results will lead to improved patient selection for treatment and inform evidence based guidelines by offering well-tested, effective, non-surgical alternatives.Show More
Waitlist

No Placebo Trial

Phase 3
Est. 5 - 8 Weeks
Steven Cohen, MD
Principal Investigator

Amniotic Suspension Allograft for Knee Osteoarthritis

Organogenesis Clinic, Napa + 1 more

This trial is testing if injecting ASA into the knee can help people with knee osteoarthritis feel better. The study will check pain levels, knee function, and safety over several months. ASA (Amniotic Suspension Allograft) has been shown to be an effective treatment for knee osteoarthritis in previous studies.Show More
Recruiting
Phase 3
Est. 4 - 6 Weeks
Unregistered Study Lead
Research Team

TG-C for Osteoarthritis of the Knee

Kolon TissueGene Clinic, Napa + 1 more

This trial tests TG-C, an injection into the knee, for patients with moderate to severe osteoarthritis. It aims to reduce pain and improve knee function by potentially modifying the disease. TG-C has shown promise in previous studies for managing knee osteoarthritis.Show More
Waitlist
Phase 3
Est. 3 - 6 Weeks
Moon Jong Noh, PhD
Study Chair

Amniotic Suspension Allograft for Osteoarthritis

Organogenesis Clinic, Sacramento + 1 more

This trial is testing a new treatment called ASA, which is injected directly into the knee joint. It aims to help patients with knee osteoarthritis by reducing pain and improving joint function. The study will compare the effects of ASA over several months.Show More
Waitlist
Phase 3
Est. 3 - 6 Weeks
Unregistered Study Lead
Research Team

Stem Cell Treatment for Knee Osteoarthritis

Nature Cell Clinic, Napa + 1 more

This trial is testing a new treatment that uses cells from a patient's own fat to help repair knee damage in people with knee osteoarthritis. The cells are injected into the knee to reduce pain and improve joint function. This type of therapy has been increasingly studied and used for treating knee osteoarthritis due to its potential to reduce pain and improve joint function.Show More
Recruiting
Phase 2 & 3
Est. 5 - 8 Weeks
Unregistered Study Lead
Research Team

Fat Cell Injection for Knee Osteoarthritis

GID BIO Clinic, Sacramento + 1 more

This trial tests if injecting special cells from a patient's own fat can reduce pain and improve function in people with knee osteoarthritis. These cells have been investigated in various studies for their potential to treat knee osteoarthritis by reducing pain and improving function.Show More
Recruiting
N/A
Est. 5 - 8 Weeks
William Cimino, PhD
Study Chair

Ankle Implant for Arthritis

Zimmer Biomet Clinic, Sacramento + 1 more

This trial studies a special ankle implant for patients needing ankle surgery. It aims to see how well the implant works in reducing pain and improving function. The implants have been developed to improve stability and longevity, with advancements in design and materials.Show More
Waitlist

No Placebo Trial

N/A
Est. 4 - 6 Weeks
Erin Osborn, MBA
Study Director

Diclofenac Gel for Osteoarthritis

Research Clinic, Sacramento + 1 more

The goal of this clinical trial is to understand the patient and clinic visit characteristics that affect health outcomes for individuals with knee osteoarthritis (OA) pain using topical diclofenac gel. The main questions it aims to answer are: * What baseline patient characteristics predict response to topical diclofenac? * Does patient physiology during the study visit predict response to topical diclofenac? * Do study visit characteristics predict response to topical diclofenac? Participants will: * attend 2 study visits to complete study questionnaires and have blood drawn * apply topical diclofenac to their knee for 8 weeks * complete biweekly questions about knee pain and diclofenac use between study visitsShow More
Waitlist

No Placebo Trial

N/A
Est. 4 - 6 Weeks
Michelle Dossett, MD, PhD
Principal Investigator

cRFA Guidance Techniques for Knee Osteoarthritis

Research Clinic, Sacramento + 1 more

Cooled radiofrequency ablation (cRFA) of the knee geniculate nerves is a promising treatment option for knee osteoarthritis, but has variable efficacy. Fluoroscopy is the typical guidance of choice, but uses bony landmarks to target these nerves which have variable positions around the knee. Alternatively, ultrasound allows for targeting based on visualization of bony landmarks, the nerves, and their accompanying vascular structures, and thus may offer greater accuracy. However, there are few studies which directly compare the clinical efficacy of these two guidance options. This study will compare these two options.Show More
Recruiting

No Placebo Trial

N/A
Est. 3 - 6 Weeks
Daniel Herman, MD
Principal Investigator
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Frequently Asked Questions

How much do osteoarthritis clinical trials pay?

Each trial will compensate patients a different amount, but $50-100 for each visit is a fairly common range. Further, most trials will cover the costs of an Uber to-and-from the clinic. Factors that can affect compensation include the phase of the trial, the length of the trial, the frequency of visits, and the specific condition being studied.

Do I need to be insured to participate in a medical study?

Clinical trials are almost always free to participants, and so do not require insurance. The only exception here are trials focused on Cancer, because only a small part of the typical treatment plan is actually experimental. For these cancer trials, participants typically need insurance to cover all the non-experimental components.

How do osteoarthritis clinical trials work?

After a researcher reviews your profile, they may choose to invite you in to a screening appointment, where they'll determine if you meet 100% of the eligibility requirements. If you do, you'll typical be sorted into one of the treatment groups, and will receive your study drug. For some trials, there is a chance you'll receive a placebo. Across osteoarthritis trials in Sacramento, 42% of clinical trials have a placebo. Typically you'll be required to check-in with the clinic every month or two. The average trial length in this city for osteoarthritis patients is 6 Months.

What does the "phase" of a clinical trial mean?

The phase of a trial reveals what stage the drug is in getting approval for a specific condition. Phase 3 trials are in the final step before approval. The drug already has data showing both safety and effectiveness. Phase 2 trials are those where the drug has some data showing safety in humans, but where effectiveness has typically only been shown in animals and non-human experiments. Phase 1 trials are the trials where we don't have safety data in humans. As a general rule, phase 3 trials are more promising than phase 2, and phase 2 trials are more promising than phase 1.

What promising new drugs are being tested?

In Sacramento, research for osteoarthritis includes treatments like Cell Therapy and medical Procedures. Specific interventions being studied are Autologous Adipose-derived Stromal Vascular Fraction and the Zimmer Trabecular Metal Total Ankle System.