Datscan

Q: What is the difference between a DaTscan and an MRI?

<p>What is the difference between DaTscan and <a href="https://www.withpower.com/clinical-trials/mri">MRI</a>? MRI provides detailed pictures of the brain, while DaTscan provides more detailed pictures of dopamine brain cells.</p>

Parkinson Disease, Single-Photon Emission Computed Tomography (SPECT)

Treatment

3 FDA approvals

0 Active Studies for Datscan

Treatment for

Parkinson Disease

What is Datscan

Ioflupane I-123The Generic name of this drug

Treatment SummaryIoflupane (I-123) is a radioactive substance used to make images of dopamine neurons in the brain and diagnose conditions such as Parkinson's disease.

DaTscanis the brand name

Datscan Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

DaTscan

Ioflupane I-123

2011

Approved as Treatment by the FDA

Ioflupane I-123, also known as DaTscan, is approved by the FDA for 3 uses such as Parkinsonian Syndromes and Single-Photon Emission Computed Tomography (SPECT) .

Parkinsonian Syndromes

Single-Photon Emission Computed Tomography (SPECT)

Parkinson Disease

Effectiveness

How Datscan Affects PatientsIodine-123 labeled ioflupane is a drug that binds to specific neurons in the brain that contain dopamine. This binding is reversible, meaning it can easily be detached, and is used to help diagnose certain conditions.

How Datscan works in the bodyIodine-123 labeled ioflupane binds to dopamine transporters in the brain. As it decays, it releases a gamma ray which can be seen on a SPECT scan.

When to interrupt dosage

The measure of Datscan is determined by the diagnosed disorder. The amount of dosage is contingent upon the mode of delivery, as outlined in the table underneath.

Condition

Dosage

Administration

Single-Photon Emission Computed Tomography (SPECT)

, 2.0 mCi/mL, 1.998 mCi/mL

, Intravenous, Injection, solution, Injection, solution - Intravenous

Parkinson Disease

, 2.0 mCi/mL, 1.998 mCi/mL

, Intravenous, Injection, solution, Injection, solution - Intravenous

Warnings

Datscan has one contraindication, so it should not be consumed in cases of the ailments specified in the following table.Datscan Contraindications

Condition

Risk Level

Notes

Pulse Frequency

Do Not Combine

There are 20 known major drug interactions with Datscan.

Common Datscan Drug Interactions

Drug Name

Risk Level

Description

Aclidinium

Minor

Ioflupane I-123 may decrease the excretion rate of Aclidinium which could result in a higher serum level.

Acrivastine

Minor

Ioflupane I-123 may decrease the excretion rate of Acrivastine which could result in a higher serum level.

Albutrepenonacog alfa

Minor

Ioflupane I-123 may decrease the excretion rate of Albutrepenonacog alfa which could result in a higher serum level.

Almasilate

Minor

Ioflupane I-123 may decrease the excretion rate of Almasilate which could result in a higher serum level.

Ancestim

Minor

Ioflupane I-123 may decrease the excretion rate of Ancestim which could result in a higher serum level.

Datscan Novel Uses: Which Conditions Have a Clinical Trial Featuring Datscan?

Zero active studies are examining the potential of Datscan in providing Single-Photon Emission Computed Tomography (SPECT) diagnosis.

Condition

Clinical Trials

Trial Phases

Single-Photon Emission Computed Tomography (SPECT)

0 Actively Recruiting

Parkinson Disease

2 Actively Recruiting

Phase 2, Early Phase 1

Patient Q&A Section about datscan

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What does a positive DaTscan mean?

"It is not definitive if a negative DaTscan means a person does not have PD, especially in early stages of the disease. However, a positive DaTscan can help confirm a diagnosis of PD. Additionally, a positive DaTscan can help to distinguish PD from essential tremor (ET) as there is no dopamine deficiency in ET."

Answered by AI

What is the difference between a DaTscan and an MRI?

"What is the difference between DaTscan and MRI? MRI provides detailed pictures of the brain, while DaTscan provides more detailed pictures of dopamine brain cells."

Answered by AI

How accurate is DaTscan for Parkinsons?

"In the study, DAT SPECT imaging was observed to have a high diagnostic accuracy of 98% for patients with clinically uncertain parkinsonism."

Answered by AI

What does a DaTscan diagnose?

"The DaTscan is a tool used to confirm the diagnosis of Parkinson's disease. It is a specific type of single-photon emission computed tomography (SPECT) imaging technique. This technique helps visualize dopamine transporter levels in the brain."

Answered by AI