Cannabis for Pain

Phase < 1

Recruiting

Research Sponsored by University of California, San Diego

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Age between 21-65 years old

If female and of childbearing potential age, not pregnant or nursing mothers

Must not have

Active pulmonary disease

Known cognitive impairment

Timeline

Screening 3 weeks

Treatment Varies

Follow Up at the first baseline testing session (session 1) and at the intervention session (session 2). all data will be collected within 2 weeks of signing consent.

Summary

This trialaims to study the brain mechanisms of cannabis to treat pain in humans, as it has been a promising therapy for many pain conditions but has yet to be clinically proven.

Who is the study for?

This trial is for adults aged 21-65 who have used cannabis before but are not currently dependent on it or using any form. They must be free from major medical conditions, psychiatric disorders like schizophrenia or bipolar disorder, and cannot be pregnant or nursing. Participants agree to avoid opioids, barbiturates, and driving within 4 hours after using study cannabis.

What is being tested?

The study is testing how vaporized cannabis (active ingredient THC) versus a placebo (no active ingredient) affects pain relief by looking at the brain's response to acute pain. Researchers aim to understand the neural mechanisms behind why cannabis might alleviate pain.

What are the potential side effects?

While specific side effects aren't listed here, typical reactions to cannabis may include dizziness, dry mouth, altered senses/perception, mood changes, slower reaction times and in some cases anxiety or discomfort.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

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I am between 21 and 65 years old.

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I am not pregnant or breastfeeding.

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I am not taking any opioid medications.

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:

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I have a lung condition that is currently causing symptoms.

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I have been diagnosed with a cognitive impairment.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ at the first baseline testing session (session 1) and at the intervention session (session 2). all data will be collected within 2 weeks of signing consent.

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~at the first baseline testing session (session 1) and at the intervention session (session 2). all data will be collected within 2 weeks of signing consent.

This trial's timeline: 3 weeks for screening, Varies for treatment, and at the first baseline testing session (session 1) and at the intervention session (session 2). all data will be collected within 2 weeks of signing consent. for reporting.