← Back to Search

Antibiotic

A Study of Levofloxacin Ocular Implant in Patients Undergoing Routine Bilateral Cataract Surgery

Phase 1
Waitlist Available
Led By Michael Coote, MD
Research Sponsored by PolyActiva Pty Ltd
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up day 90
Awards & highlights
All Individual Drugs Already Approved
No Placebo-Only Group
Approved for 5 Other Conditions

Summary

This trial involves patients who are having cataract surgery on both eyes. One eye will receive standard eye drops, while the other will get a small device that releases an antibiotic directly into the eye. The goal is to see if the implant can better prevent infections compared to regular eye drops.

Eligible Conditions
  • Cataract
  • Pseudoaphakia

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~day 90
This trial's timeline: 3 weeks for screening, Varies for treatment, and day 90 for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Levofloxacin concentration in aqueous humor at Day 5 in treated eyes
Safety of the Levofloxacin Ocular Implant
Secondary study objectives
Number of actuations required to administer the implant

Awards & Highlights

All Individual Drugs Already Approved
Therapies where all constituent drugs have already been approved are likely to have better-understood side effect profiles.
No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.
Approved for 5 Other Conditions
This treatment demonstrated efficacy for 5 other conditions.

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: Levofloxacin Ocular ImplantExperimental Treatment1 Intervention
Biphasic levofloxacin antibiotic implant
Group II: ControlActive Control1 Intervention
Commercially available topical medications as per LEVO-CS102 Surgical Therapy Procedure.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Levofloxacin
FDA approved

Find a Location

Who is running the clinical trial?

PolyActiva Pty LtdLead Sponsor
4 Previous Clinical Trials
51 Total Patients Enrolled
1 Trials studying Cataract
5 Patients Enrolled for Cataract
Michael Coote, MDPrincipal InvestigatorMelbourne Eye Specialists
~0 spots leftby Dec 2025
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Back to top