Pig Kidney Transplant for Kidney Failure
Trial Summary
What is the purpose of this trial?
This trial involves transplanting kidneys from genetically modified pigs into patients with end-stage kidney disease. The pig kidneys are altered to be less likely rejected by the human body, and patients will take medications to suppress their immune system. Pig kidneys have been used in studies with animals, showing promise for future clinical trials.
Research Team
Jayme E Locke, MD
Principal Investigator
University of Alabama at Birmingham
Eligibility Criteria
This trial is for adults aged 18-75 with end-stage kidney disease who are on dialysis, listed for a kidney transplant at UAB, and live within an hour of the hospital. They must be willing to get standard vaccinations and have factors like high waitlist mortality risk or long wait times. Pregnant individuals, those with severe diseases or psychiatric conditions, drug/alcohol abusers, and anyone unable to follow the study plan cannot join.Inclusion Criteria
Exclusion Criteria
Treatment Details
Interventions
- Porcine Kidney Xenotransplantation (Xenotransplantation)
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Alabama at Birmingham
Lead Sponsor
Kierstin Kennedy
University of Alabama at Birmingham
Chief Medical Officer since 2022
MD
S. Dawn Bulgarella
University of Alabama at Birmingham
Chief Executive Officer since 2023
BSc in Commerce and Business Administration from the University of Alabama, MS in Health Administration from the University of Alabama at Birmingham
United Therapeutics
Industry Sponsor
Dr. Martine Rothblatt
United Therapeutics
Chief Executive Officer since 1996
PhD in Medical Ethics from the Royal London College of Medicine and Dentistry, JD and MBA from UCLA
Dr. Michael Benkowitz
United Therapeutics
Chief Medical Officer since 2023
MD from Harvard Medical School
Lung Biotechnology PBC
Industry Sponsor