Egg White Powder for High Blood Sugar and High Blood Pressure

Phase 1

Waitlist Available

Led By Jianping Wu, PhD

Research Sponsored by University of Alberta

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Individuals at risk of diabetes/having type 2 diabetes: Fasting glucose levels at or above 6.0 mmol/L

Healthy control group: Normal weight (BMI below 25 kg/m2 or Asian population below 23 kg/m2)

Must not have

Individuals aged above 70 years

Individuals with poorly controlled diabetes (HbA1c above 12.0%) or taking exogenous insulin will be excluded. Other anti-diabetic and lipid-lowering medications will be documented

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 60, 120, and 180 minutes after consumption of the smoothie

Summary

"This trial is investigating the potential benefits of a bioactive peptide called IRW, derived from egg white hydrolysate, for managing high blood sugar and blood pressure. Participants at risk for or with type

Who is the study for?

This trial is for individuals at high risk of type 2 diabetes or those already diagnosed with it. They should be willing to consume a standardized breakfast with a smoothie containing different protein powders on four separate days, each one week apart. Healthy controls will participate in just one treatment.

What is being tested?

The study is testing the health effects of IRW, a bioactive peptide from egg white hydrolysate, on managing high blood sugar and pressure. Participants will receive this ingredient through smoothies during their breakfast to see if there's an acute benefit.

What are the potential side effects?

Since the intervention involves food-derived peptides, side effects might include potential allergic reactions or gastrointestinal discomfort; however, specific side effects are not detailed as this is an initial feasibility study.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

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My fasting blood sugar level is 6.0 mmol/L or higher.

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I am of normal weight according to BMI standards.

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My fasting blood sugar is below 5.6 mmol/L.

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My blood pressure is below 130/85 mmHg.

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I am overweight or obese according to BMI standards for diabetes risk.

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:

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I am over 70 years old.

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My diabetes is well-controlled, and I am not on insulin.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 30, 60, 90, 120, and 180 minutes after consumption of the smoothie

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~30, 60, 90, 120, and 180 minutes after consumption of the smoothie

This trial's timeline: 3 weeks for screening, Varies for treatment, and 30, 60, 90, 120, and 180 minutes after consumption of the smoothie for reporting.