Stem Cell Therapy for Lung Disease
(ADcSVF-COPD Trial)

Recruiting in Palo Alto (17 mi)

+1 other location

Dr. Robert W Alexander, MD - Plastic ...

Overseen byRobert W Alexander, MD

Age: 18+

Sex: Any

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Phase 1 & 2

Waitlist Available

Sponsor: Healeon Medical Inc

No Placebo Group

Trial Summary

What is the purpose of this trial?

This trial is testing a new treatment for COPD that involves injecting special cells from fat tissue into the bloodstream. It aims to help patients who do not get better with usual treatments by reducing lung inflammation and improving breathing.

Research Team

Robert W Alexander, MD

Principal Investigator

Healeon Medical Inc

Glenn C. Terry, MD

Principal Investigator

Global Alliance for Regenerative Medicine (GARM)

Eligibility Criteria

This trial is for adults with moderate to severe COPD, a lung condition causing poor airflow and difficulty breathing. Candidates must not have hepatitis (except past Hepatitis A), drug/alcohol dependence, life expectancy under 3 months due to other illnesses, inherited Alpha-1 Antitrypsin Deficiency, or be pregnant/lactating. They shouldn't have used investigational drugs within the last month or be on chronic immunosuppressive/chemotherapy treatments.

Inclusion Criteria

I have been diagnosed with moderate to severe COPD.

My COPD is moderate to very severe.

Exclusion Criteria

I have Alpha-1 Antitrypsin Deficiency.

I am unable or unwilling to understand or sign a consent form.

I am on long-term medication to suppress my immune system or for chemotherapy.

See 6 more

Treatment Details

Interventions

AD-cSVF (Stem Cell Therapy)

Trial OverviewThe study tests the safety and effectiveness of using one's own adipose-derived stem/stromal cells (ADcSVF) obtained via lipoaspiration in treating COPD symptoms. It involves comparing results from this new intervention against normal saline IV treatment as a control.

Participant Groups

3Treatment groups

Experimental Treatment

Group I: Normal Saline IV Arm 3Experimental Treatment1 Intervention

Normal Saline IV with AD-cSVF cells

Group II: Lipoaspiration Arm 1Experimental Treatment1 Intervention

Acquisition of Adipose-Derived tissue Stromal Vascular Fraction (AD-tSVF) via closed syringe harvest subdermal fat

Group III: AD-cSVF Arm 2Experimental Treatment1 Intervention

Isolation of cellular stem/stromal cells from subdermal adipose-derived cellular stromal vascular fraction (AD-cSVF)