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What is Butisol Sodium
ButabarbitalThe Generic name of this drug
Treatment SummaryButabarbital is a type of barbiturate that works quickly but has a shorter-lasting effect than other barbiturates. It is used to treat severe insomnia and pre-operative anxiety, although it is less commonly prescribed due to its high potential for abuse. Butabarbital was approved by the FDA in 1939.
Butisol Sodiumis the brand name
Butisol Sodium Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Butisol Sodium
Butabarbital
1939
3
Approved as Treatment by the FDA
Butabarbital, also known as Butisol Sodium, is approved by the FDA for 3 uses such as Sedation and induction of Sedation .Sedation
induction of Sedation
Insomnia
Effectiveness
How Butisol Sodium Affects PatientsButabarbital helps the body relax and fall asleep by increasing the activity of neurotransmitters that cause relaxation and decreasing the activity of those that cause alertness. Its effects last for around 6-8 hours. It can be used safely in most people, but some may experience increased drowsiness, falls, and complex behavior while not completely awake.
How Butisol Sodium works in the bodyButabarbital is a type of barbiturate that makes it harder for neurons to fire. It does this by making GABA-A receptors more sensitive, so they can shut off neurons more easily. It also stops neuron cells from firing by blocking acetylcholine and kainate receptors. This produces a sedative effect.
When to interrupt dosage
The proposed measure of Butisol Sodium relies upon the diagnosed situation, such as Sedation, Insomnia and initiation of Sedation. The quantity of dosage is contingent upon the delivery system (e.g. Tablet, coated or Tablet - Oral) presented in the table underneath.Condition
Dosage
Administration
Insomnia
, 30.0 mg, 15.0 mg, 100.0 mg, 50.0 mg, 30.0 mg/mL
, Oral, Tablet, Tablet - Oral, Tablet, coated, Tablet, coated - Oral, Solution, Solution - Oral
induction of Sedation
, 30.0 mg, 15.0 mg, 100.0 mg, 50.0 mg, 30.0 mg/mL
, Oral, Tablet, Tablet - Oral, Tablet, coated, Tablet, coated - Oral, Solution, Solution - Oral
Sedation
, 30.0 mg, 15.0 mg, 100.0 mg, 50.0 mg, 30.0 mg/mL
, Oral, Tablet, Tablet - Oral, Tablet, coated, Tablet, coated - Oral, Solution, Solution - Oral
Warnings
Butisol Sodium ContraindicationsCondition
Risk Level
Notes
Porphyrias
Do Not Combine
Porphyrias
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Butabarbital may interact with Pulse Frequency
Common Butisol Sodium Drug Interactions
Drug Name
Risk Level
Description
Azelastine
Major
Butabarbital may increase the central nervous system depressant (CNS depressant) activities of Azelastine.
Deutetrabenazine
Major
The risk or severity of sedation and somnolence can be increased when Butabarbital is combined with Deutetrabenazine.
Eluxadoline
Major
The risk or severity of constipation can be increased when Butabarbital is combined with Eluxadoline.
Ethanol
Major
Butabarbital may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Meperidine
Major
Butabarbital may increase the hypotensive and central nervous system depressant (CNS depressant) activities of Meperidine.
Butisol Sodium Toxicity & Overdose RiskTaking too much of this drug can lead to unsteady walking, slurred speech, involuntary eye movements, confusion, bad decision-making, irritability, and insomnia. More severe overdoses can cause extreme drowsiness, shallow breathing, very little urination, a fast heartbeat, low blood pressure, a low body temperature, a coma, and shock. In the most extreme cases, a person may appear to be dead, but it is possible to reverse this if their brain has not been deprived of oxygen. Treatment for an overdose consists of managing the symptoms and providing support.
Butisol Sodium Novel Uses: Which Conditions Have a Clinical Trial Featuring Butisol Sodium?
84 ongoing trials are assessing the potential of Butisol Sodium in providing Insomnia relief, Sedation, and induction of Sedation.Condition
Clinical Trials
Trial Phases
Insomnia
1 Actively Recruiting
Not Applicable
Sedation
2 Actively Recruiting
Phase 3, Not Applicable
induction of Sedation
0 Actively Recruiting
Patient Q&A Section about butisol sodium
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.What schedule drug is Butisol?
"Butabarbital, known as Butisol commercially, is an approved drug in the US and Canada used in the short-term treatment of anxiety disorders and as a sedative aid before surgery."
Answered by AI
What is Butisol sodium?
"Butisol Sodium is a non-selective central nervous system depressant that is used as a sedative or hypnotic."
Answered by AI
What is Butisol sodium used for?
"The following is a description of the medication Butisol, which is a barbiturate used for sleep. It is faster-working than other sleep medications, but can be habit-forming and addictive."
Answered by AI
Is Butisol still available?
"As of August 10, 2022, all of the above formulations have been discontinued."
Answered by AI