Oxytocin for Alcoholism and Healthy Controls

Recruiting in Palo Alto (17 mi)

Overseen byTiffany Love, PhD

Age: 18 - 65

Sex: Any

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Phase 2

Waitlist Available

Sponsor: University of Utah

Prior Safety Data

Trial Summary

What is the purpose of this trial?

The proposed study will investigate the effects of intranasal oxytocin administration on neural activity associated with social and non-social motivation.

Eligibility Criteria

This study is for people aged 18-45 who can handle an MRI scan without issues like metal implants or claustrophobia. It's not for those with serious medical conditions, pregnant/nursing women, or anyone allergic to oxytocin. Participants shouldn't be on certain medications including antipsychotics and antidepressants.

Inclusion Criteria

I am between 18 and 45 years old.

Exclusion Criteria

Unable to comply with study procedures or protocols

I do not have untreated illnesses or a history of serious liver, kidney, brain issues, nose conditions, or major head surgeries.

I am not currently on certain mental health meds or have taken specific drugs in the past 6 months.

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Treatment Details

Interventions

Oxytocin (Peptide Hormone)
Placebo (Behavioural Intervention)

Trial OverviewThe trial tests how a nasal spray of oxytocin versus a placebo affects brain activity related to motivation in both social and non-social contexts, using fMRI scans to observe changes.

Participant Groups

2Treatment groups

Experimental Treatment

Placebo Group

Group I: OxytocinExperimental Treatment1 Intervention

Each participant will be studied using fMRI following self-administration of oxytocin.

Group II: PlaceboPlacebo Group1 Intervention

Each participant will be studied using fMRI following self-administration of placebo.

Oxytocin is already approved in United States, European Union, Canada, Australia for the following indications:

🇺🇸 Approved in United States as Pitocin for: