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Vitamin
Nicotinamide riboside for Small Fiber Neuropathy
Phase 2
Waitlist Available
Led By Ahmet Hoke
Research Sponsored by Johns Hopkins University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 3 months
Summary
This trial will test if a nutritional supplement called nicotinamide riboside can prevent and repair nerve damage caused by applying capsaicin to the skin in healthy people. The study aims to see if this supplement can help nerves stay healthy and grow back after damage.
Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ 3 months
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~3 months
Treatment Details
Study Objectives
Study objectives can provide a clearer picture of what you can expect from a treatment.Primary study objectives
Denervation of Skin
Reinnervation of Skin
Trial Design
2Treatment groups
Experimental Treatment
Placebo Group
Group I: Nicotinamide RibosideExperimental Treatment1 Intervention
Experimental group of participants will receive Nicotinamide riboside at a dose of 900 mg twice a day orally.
Group II: PlaceboPlacebo Group1 Intervention
Study participants in the placebo arm will receive placebo pills that are similar in size and shape to the experimental group drug.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Nicotinamide riboside
2021
Completed Phase 3
~390
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Who is running the clinical trial?
Johns Hopkins UniversityLead Sponsor
2,326 Previous Clinical Trials
14,874,914 Total Patients Enrolled
2 Trials studying Small Fiber Neuropathy
11 Patients Enrolled for Small Fiber Neuropathy
Adelson Medical Research FoundationUNKNOWN
Ahmet HokePrincipal InvestigatorJohns Hopkins University
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