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Behavioural Intervention

Virtual Care for Acute Kidney Injury (UPTAKE-VC Trial)

N/A
Waitlist Available
Led By Matthew James, MD
Research Sponsored by University of Calgary
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Age ≥ 18 years old
Hospitalization > 48 hours
Must not have
Kidney failure receiving dialysis
Will be discharged to long-term care
Timeline
Screening 3 weeks
Treatment Varies
Follow Up at 45 days after the date of randomization
Awards & highlights

Summary

This trial aims to improve outcomes for patients with Acute Kidney Injury (AKI) by implementing strategies to reduce hospital stay length, readmission rates, and improve long-term outcomes. The study involves

Who is the study for?
This trial is for hospitalized adults with Acute Kidney Injury (AKI) who are at high risk of being readmitted to the hospital or dying. The study aims to help these individuals by using virtual care strategies.
What is being tested?
The UPTAKE trial is testing a virtual home hospital system with remote monitoring against usual care for AKI patients. It's a randomized controlled trial, meaning people are put into groups by chance, and it will last three years.
What are the potential side effects?
Since this intervention involves virtual care rather than medication, traditional side effects aren't expected. However, there may be technical issues or challenges in communication that could affect patient care.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
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I am 18 years old or older.
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I have been hospitalized for more than 48 hours.
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My LACE score is 12 or higher.

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:
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I am on dialysis for kidney failure.
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I will be moving to a long-term care facility after discharge.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~at 45 days after the date of randomization
This trial's timeline: 3 weeks for screening, Varies for treatment, and at 45 days after the date of randomization for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
the number of days alive out of hospital
Secondary study objectives
Changes to medication prescription
Emergency Department visits
Estimated Glomerular Filtration (eGFR)
+9 more

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: Virtual CareExperimental Treatment1 Intervention
Participants will receive virtual care through Virtual Home Hospital programs in Alberta for their hospital to home transition of care.
Group II: Usual CareActive Control1 Intervention
Participants will be discharged as per usual care practices from hospital to their home.

Find a Location

Who is running the clinical trial?

University of CalgaryLead Sponsor
805 Previous Clinical Trials
883,678 Total Patients Enrolled
2 Trials studying Acute Kidney Injury
9,415 Patients Enrolled for Acute Kidney Injury
Alberta Health servicesOTHER
162 Previous Clinical Trials
650,660 Total Patients Enrolled
3 Trials studying Acute Kidney Injury
15,461 Patients Enrolled for Acute Kidney Injury
Matthew James, MDPrincipal InvestigatorUniversity of Calgary
1 Previous Clinical Trials
155 Total Patients Enrolled
1 Trials studying Acute Kidney Injury
155 Patients Enrolled for Acute Kidney Injury
~236 spots leftby Aug 2026
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