Prehabilitation Program for Cancer Surgery
(RIOT Trial)

Recruiting in Palo Alto (17 mi)

Overseen byMark Rubinstein, PhD

Age: 18+

Sex: Any

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Academic

Waitlist Available

Sponsor: Ohio State University Comprehensive Cancer Center

No Placebo Group

Trial Summary

What is the purpose of this trial?This trial studies how well a prehabilitation program works to improve patient outcomes after surgery compared to the normal standard of care prehabilitation in frail patients undergoing surgery for pancreatic, liver, or gastric cancer. Frailty is defined as the pathophysiology of aging or through the accumulation of physiologic and functional deficits. Prehabilitation programs seek to optimize the medical and physical state of patients prior to undergoing surgery with the goal of improving outcomes following surgery. Despite evidence for its importance in health outcomes for frail patients, prehabilitation programs have not been well studied in cancer surgery populations. This trial may provide researchers with more information on how to improve patient outcomes after cancer surgery through the use of prehabilitation programs.

Eligibility Criteria

This trial is for frail patients who are scheduled for abdominal cancer surgery (pancreatic, liver, or gastric) or planned to have it after neoadjuvant therapy. It's aimed at those who can provide informed consent and speak English. People in prison or unable to give consent cannot participate.

Inclusion Criteria

I am planned for treatment to shrink my tumor before surgery.

I am scheduled for surgery related to abdominal cancer.

Exclusion Criteria

I am unable to understand and give consent for treatment.

I do not speak English.

Prisoners

Participant Groups

The study is testing a prehabilitation program designed to improve patient health before surgery against the usual care given before such surgeries. The goal is to see if this program leads to better recovery outcomes for patients with pancreatic, liver, or gastric cancer.

2Treatment groups

Experimental Treatment

Active Control

Group I: Arm I (physical therapy consultation, exercise intervention)Experimental Treatment3 Interventions

Patients undergo a physical therapy consultation and complete home exercises 3 days per week.

Group II: Arm II (best practice)Active Control2 Interventions

Patients receive standard of care.