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Singing Therapy for Cardiovascular Health

N/A

Waitlist Available

Research Sponsored by Medical College of Wisconsin

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up after 30-minute singing (and sham) interventions

Summary

This trial is testing whether singing can help improve cardiovascular biomarkers in older patients with CVD.

Who is the study for?

This trial is for older adults with a history of coronary artery disease who speak English. It's not suitable for those with pacemakers, ICDs, certain heart rhythm problems, Parkinson's disease or tremors, amputated upper extremity or arm fistula, thickened fingernails due to fungus, pregnant women, drug or heavy alcohol users, unstable coronary heart disease patients, stroke/TIA survivors within five years of cancer treatment requiring systemic therapy.

What is being tested?

The study investigates if singing can improve cardiovascular health in older adults with heart disease. Participants will either sing with a music therapist or follow a guided video; there's also a control group that won't sing. The focus is on how singing affects biomarkers like endothelial function and heart rate variability after 30 minutes.

What are the potential side effects?

Since the intervention involves non-strenuous activity such as singing under guidance without medical treatments involved, significant side effects are not anticipated beyond the normal risks associated with light physical activity.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ after 30-minute singing (and sham) interventions

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~after 30-minute singing (and sham) interventions

This trial's timeline: 3 weeks for screening, Varies for treatment, and after 30-minute singing (and sham) interventions for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.

Primary study objectives

change in vascular (endothelial) function

Secondary study objectives

cardiac hemodynamics

level of exertion achieved during singing

Other study objectives

Visual Mood Score

the change in TNF-alpha, IL-1 Beta, IL-6, and IL-8

Trial Design

3Treatment groups

Active Control

Placebo Group

Group I: Singing intervention 2Active Control1 Intervention

In-person music therapy session. The music therapist will continue to coach throughout the 30-minute session. Flow Mediated dilation (FMD) and EndoPAT will be measured before and after singing.

Group II: Singing intervention 1Active Control1 Intervention

Instructional sing-a-long video. A video series will be created and recorded for the purposes of the study. Flow Mediated dilation (FMD) and EndoPAT will be measured before and after singing.

Group III: Control/sham interventionPlacebo Group1 Intervention

Subjects will have a 30-minute period of rest sitting upright (as they would be positioned for the singing interventions). This arm is meant to isolate the specific effects of the treatment rather than the potential "incidental" effects related to the research setting and measurements. During this time, subjects will undergo hearing testing. Flow Mediated dilation (FMD) and EndoPAT will be measured before and after the 30 minute rest.

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