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Proton Pump Inhibitor

1 for Non-Allergic Rhinitis

N/A
Waitlist Available
Led By David A Khan, MD
Research Sponsored by University of Texas Southwestern Medical Center
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
* age between 18-80, symptoms of perennial rhinitis, negative epicutaneous skin testing to a panel of common aeroallergens, and ability to speak English
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up last two weeks of each treatment arm
Awards & highlights
Approved for 5 Other Conditions
All Individual Drugs Already Approved

Summary

The purpose of this study was to see if high dose esomeprazole (40mg bid) was effective in treating non-allergic rhinitis

Eligible Conditions
  • Non-Allergic Rhinitis

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~last two weeks of each treatment arm
This trial's timeline: 3 weeks for screening, Varies for treatment, and last two weeks of each treatment arm for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Total Nasal Symptom Scores

Awards & Highlights

Approved for 5 Other Conditions
This treatment demonstrated efficacy for 5 other conditions.
All Individual Drugs Already Approved
Therapies where all constituent drugs have already been approved are likely to have better-understood side effect profiles.

Trial Design

2Treatment groups
Experimental Treatment
Placebo Group
Group I: 1Experimental Treatment1 Intervention
esomeprazole 40mg po bid
Group II: 2Placebo Group1 Intervention
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Esomeprazole
FDA approved

Find a Location

Who is running the clinical trial?

AstraZenecaIndustry Sponsor
4,394 Previous Clinical Trials
289,121,249 Total Patients Enrolled
University of Texas Southwestern Medical CenterLead Sponsor
1,080 Previous Clinical Trials
1,056,246 Total Patients Enrolled
David A Khan, MDPrincipal InvestigatorDepartment of Allergy and Immunology, UT Southwestern
1 Previous Clinical Trials
300 Total Patients Enrolled
~2 spots leftby Nov 2025
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