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Exercise Training for Long-Term COVID-19 Effects
N/A
Recruiting
Led By Bryan Taylor, PhD
Research Sponsored by Mayo Clinic
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 8 weeks
Awards & highlights
No Placebo-Only Group
Summary
This trial is testing if exercise can help improve the long term effects of COVID-19, like lung and heart function.
Who is the study for?
This trial is for adults aged 21-75 who have recovered from COVID-19, confirmed by RT-PCR test. Participants should not be clinically obese or have conditions limiting exercise. They must be free of heart issues during rest and exertion and able to consent in writing.
What is being tested?
The study aims to assess the long-term effects of COVID-19 on physical health and whether exercise training can improve lung and heart function, fitness levels, and reduce lingering symptoms in those recovering from the virus.
What are the potential side effects?
While specific side effects are not listed for exercise training, typical risks may include muscle soreness, fatigue, shortness of breath during activity, or exacerbation of underlying conditions if present.
Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ 8 weeks
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~8 weeks
Treatment Details
Study Objectives
Study objectives can provide a clearer picture of what you can expect from a treatment.Primary study objectives
Maximal oxygen update (VO2max) measured in mL/kg/min
Secondary study objectives
Forced expiratory volume in 1 second (FEV1) measured in L
Forced vital capacity (FVC) measured in L
Left ventricular contractile function measured as % fractional area change (LV FAC)
+4 moreAwards & Highlights
No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.
Trial Design
2Treatment groups
Experimental Treatment
Active Control
Group I: Interventional (exercise training) GroupExperimental Treatment1 Intervention
8 week home-based exercise training
Group II: Control GroupActive Control1 Intervention
Standard physician-guided medical care after COVID-19
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Who is running the clinical trial?
Mayo ClinicLead Sponsor
3,343 Previous Clinical Trials
3,062,302 Total Patients Enrolled
Bryan Taylor, PhDPrincipal InvestigatorMayo Clinic
2 Previous Clinical Trials
80 Total Patients Enrolled
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Eligibility Criteria:
This trial includes the following eligibility criteria:- You are unable to participate in exercise training because of an injury or a condition that could make it risky for you to exercise.You have been declared as fully recovered from a SARS-CoV-2 infection.You are younger than 21 or older than 75 years old.You have had a confirmed SARS-CoV-2 infection detected by RT-PCR test in the past.You are between 21 and 75 years old.You are not severely overweight or have health conditions that make it hard for you to exercise.Your heart does not show signs of reduced blood flow during rest or physical activity, as seen in an ECG test.
Research Study Groups:
This trial has the following groups:- Group 1: Control Group
- Group 2: Interventional (exercise training) Group
Awards:
This trial has 1 awards, including:- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
Timeline:
This trial has the following timeline:- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
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