TEE Techniques for Swallowing Difficulty After Lung Transplant

N/A

Recruiting

Led By J.Prince Neelankavil, MD

Research Sponsored by University of California, Los Angeles

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Single or double lung transplantation

Be older than 18 years old

Must not have

Contraindications to TEE including: perforated esophagus, esophageal stricture, esophageal tumor, and history of an esophagectomy

Patients that require a tracheostomy postoperatively.

Timeline

Screening 3 weeks

Treatment Varies

Follow Up pod0 until discharge from the hospital. an average of 5-10 days until discharge from the hospital. a maximum of 30 days for in-hospital mortality.

Awards & highlights

No Placebo-Only Group

Summary

This trial is investigating if reducing the number of pictures taken of the heart during a lung transplant can reduce difficulty swallowing after surgery.

Who is the study for?

This trial is for adult patients undergoing single or double lung transplantation at UCLA. It's not suitable for individuals with conditions like a perforated esophagus, narrowed esophagus, esophageal cancer, or those who have had their esophagus removed. Patients needing a tracheostomy after surgery are also excluded.

What is being tested?

The study tests if limiting the number of TEE (heart imaging from inside the body) clips during lung transplant surgery can reduce swallowing difficulties afterwards. Participants will be randomly assigned to two groups: one with limited TEE clips and another where the attending anesthesiologist decides on the number of clips.

What are the potential side effects?

While this trial focuses on dysphagia as an outcome rather than side effects of medication, potential risks may include discomfort from TEE and complications related to fewer diagnostic images being available during surgery.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

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I have had a lung transplant.

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:

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I do not have any conditions that make throat exams unsafe, like a torn esophagus or throat surgery history.

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I will need a tracheostomy after surgery.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ pod0 until discharge from the hospital. an average of 5-10 days until discharge from the hospital. a maximum of 30 days for in-hospital mortality.

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~pod0 until discharge from the hospital. an average of 5-10 days until discharge from the hospital. a maximum of 30 days for in-hospital mortality.

This trial's timeline: 3 weeks for screening, Varies for treatment, and pod0 until discharge from the hospital. an average of 5-10 days until discharge from the hospital. a maximum of 30 days for in-hospital mortality. for reporting.