Non-invasive Esophageal Testing for Swallowing Disorders

Recruiting in Palo Alto (17 mi)

Overseen byDhyanesh Patel, MD

Age: 18+

Sex: Any

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Academic

Waitlist Available

Sponsor: Vanderbilt University Medical Center

No Placebo Group

Trial Summary

What is the purpose of this trial?The investigator proposes to study electrical activity reflective of esophageal motility in adults noninvasively by the use of multichannel electroesophagogram (EESG) and magnetoesophagogram (MESG) recordings.

Eligibility Criteria

This trial is for adults over 18 with no gastrointestinal issues, or those getting routine checks for esophageal motility. It's not for people with MRI contraindications like pacemakers, severe obesity, heart rhythm problems, anticoagulant use, or claustrophobia.

Inclusion Criteria

I am 18 or older and getting an HRM test for esophagus issues.

I am over 18 and do not have any known stomach or intestine problems.

Exclusion Criteria

You are extremely overweight and may not fit comfortably under the SQUID device being used in the study.

I do not have a history of heart rhythm problems nor am I on blood thinners.

You are afraid of being in small spaces and cannot stay still during the required test.

+1 more

Participant Groups

The study tests noninvasive methods to record esophageal activity in adults using EESG and MESG alongside High resolution manometry (HRM), which are techniques to measure muscle function and movements of the esophagus.

3Treatment groups

Active Control

Group I: Achalasia subjectsActive Control4 Interventions

Subjects who have undergone standard of care high resolution manometry that results in a diagnosis of achalasia will be given questionnaires and testing by electroesophagogram (EESG) and magnetoesophagogram (MESG).

Group II: Hypercontractile/spastic disorder subjectsActive Control4 Interventions

Subjects who have undergone standard of care high resolution manometry that results in a diagnosis of hypercontractile/spastic disorder will be given questionnaires and testing by electroesophagogram (EESG) and magnetoesophagogram (MESG).

Group III: Healthy ControlsActive Control3 Interventions

Healthy volunteers with no known gastrointestinal complications will be given questionnaires and testing by electroesophagogram (EESG) and magnetoesophagogram (MESG).