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Procedure

Air Bolus Effects for Swallowing Disorders

N/A

Recruiting

Research Sponsored by Medical College of Wisconsin

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Age 21 to 90 years

Male and female subject with no history or present diagnosis of pharyngo-esophageal diseases or motility disorders

Must not have

Under the age of 21

Over the age of 90

Timeline

Screening 3 weeks

Treatment Varies

Follow Up through study completion, an average of 1 year

Awards & highlights

No Placebo-Only Group

Summary

This trial aims to study how a food bolus moves from the throat to the upper part of the esophagus and triggers the muscle contractions that push the food down the esophagus.

Who is the study for?

This trial is for individuals with swallowing disorders. Specific eligibility criteria are not provided, so it's important to contact the study organizers for detailed information on who can participate.

What is being tested?

The trial is studying how an air bolus affects the movement of muscles in the throat and esophagus using a technique called high-resolution manometry, which measures muscle pressure.

What are the potential side effects?

Potential side effects are not explicitly listed but may include discomfort from the manometry procedure and minor throat irritation.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

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I am between 21 and 90 years old.

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I have never had throat or swallowing disorders.

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:

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I am under 21 years old.

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I am over 90 years old.

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I have a throat or swallowing disorder.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ through study completion, an average of 1 year

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~through study completion, an average of 1 year

This trial's timeline: 3 weeks for screening, Varies for treatment, and through study completion, an average of 1 year for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.

Primary study objectives

esophageal clearance time

peristaltic wave velocity

smooth esophageal muscle contractile integral

+1 more

Awards & Highlights

No Placebo-Only Group

All patients enrolled in this study will receive some form of active treatment.

Trial Design

1Treatment groups

Experimental Treatment

Group I: Healthy adultsExperimental Treatment1 Intervention

Pharyngo-esophageal high resolution manometry with affixed single-lumen, end-hole catheter wherein one end of the single lumen catheter is in the pharynx and the other is connected to an external stopcock to vent or not vent the pharynx to atmosphere during twenty dry swallows (10 vented, 10 unvented).

0 / 5Eligibility criteria met